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Found 156 with Last Name = 'hillier' and Initial = 'j'
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554469(CHEMBL4796694)copy SMILES
Affinity DataIC50: 0.0510nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554470(CHEMBL4752559)copy SMILES
Affinity DataIC50: 0.0750nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554475(CHEMBL4757064)copy SMILES
Affinity DataIC50: 0.190nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554462(CHEMBL4784029)copy SMILES
Affinity DataIC50: 0.190nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554479(CHEMBL4741570)copy SMILES
Affinity DataIC50: 0.260nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554471(CHEMBL4761454)copy SMILES
Affinity DataIC50: 0.260nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554472(CHEMBL4787488)copy SMILES
Affinity DataIC50: 0.270nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554464(CHEMBL4750152)copy SMILES
Affinity DataIC50: 0.350nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554484(CHEMBL4747825)copy SMILES
Affinity DataIC50: 0.430nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554480(CHEMBL4757561)copy SMILES
Affinity DataIC50: 0.450nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554467(CHEMBL4759088)copy SMILES
Affinity DataIC50: 0.460nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554477(CHEMBL2426243)copy SMILES
Affinity DataIC50: 0.780nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50154397(CHEMBL3774760)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554476(CHEMBL4782633)copy SMILES
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554465(CHEMBL4776064)copy SMILES
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554457(CHEMBL4793575)copy SMILES
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554483(CHEMBL4085008)copy SMILES
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554473(CHEMBL4754273)copy SMILES
Affinity DataIC50: 2nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554456(CHEMBL4791705)copy SMILES
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554481(CHEMBL4743027)copy SMILES
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554468(CHEMBL4749659)copy SMILES
Affinity DataIC50: 3nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554478(CHEMBL4763193)copy SMILES
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554474(CHEMBL4761164)copy SMILES
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50427205(CHEMBL2324854)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539248(CHEMBL4633059)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554458(CHEMBL4794717)copy SMILES
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554486(CHEMBL4079629)copy SMILES
Affinity DataIC50: 6.70nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554485(CHEMBL4758707)copy SMILES
Affinity DataIC50: 11nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554450(CHEMBL4760228 | US11634391, Compound 196)copy SMILES
Affinity DataIC50: 13nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554482(CHEMBL4786162)copy SMILES
Affinity DataIC50: 13nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554455(CHEMBL4799989)copy SMILES
Affinity DataIC50: 15nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554460(CHEMBL4788846)copy SMILES
Affinity DataIC50: 18nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554463(CHEMBL4745403)copy SMILES
Affinity DataIC50: 18nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554466(CHEMBL4744661)copy SMILES
Affinity DataIC50: 27nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554459(CHEMBL4780504)copy SMILES
Affinity DataIC50: 31nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554451(CHEMBL4756992)copy SMILES
Affinity DataIC50: 31nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554452(CHEMBL4762374)copy SMILES
Affinity DataIC50: 32nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554453(CHEMBL4789348)copy SMILES
Affinity DataIC50: 33nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50427208(CHEMBL554820)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539249(CHEMBL4441123)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50543229(CHEMBL4637220)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of human Notum (S81 to T451 residues) Cys330Ser mutant expressed in HEK293S GnTI cells using OPTS as substrate incubated for 40 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50543229(CHEMBL4637220)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50543200(CHEMBL4646852)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of human Notum (S81 to T451 residues) Cys330Ser mutant expressed in HEK293S GnTI cells using OPTS as substrate incubated for 40 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0JNHPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50361164(CHEMBL4174188)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Covalent inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluoresc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50543199(CHEMBL4639422)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of human Notum (S81 to T451 residues) Cys330Ser mutant expressed in HEK293S GnTI cells using OPTS as substrate incubated for 40 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0JNHPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50543225(CHEMBL4634413)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of human Notum (S81 to T451 residues) Cys330Ser mutant expressed in HEK293S GnTI cells using OPTS as substrate incubated for 40 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50543192(CHEMBL4646972)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of human Notum (S81 to T451 residues) Cys330Ser mutant expressed in HEK293S GnTI cells using OPTS as substrate incubated for 40 mins by fl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0JNHPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50543238(CHEMBL4644041)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of human Notum (S81 to T451 residues) Cys330Ser mutant expressed in HEK293S GnTI cells using OPTS as substrate incubated for 40 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0JNHPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50543196(CHEMBL4645096)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibition of human Notum (S81 to T451 residues) Cys330Ser mutant expressed in HEK293S GnTI cells using OPTS as substrate incubated for 40 mins by fl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0JNHPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50543230(CHEMBL4632764)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of human Notum (S81 to T451 residues) Cys330Ser mutant expressed in HEK293S GnTI cells using OPTS as substrate incubated for 40 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0JNHPubMed
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