Compile Data Set for Download or QSAR
Found 114 with Last Name = 'holstein' and Initial = 'j'
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM202553((E/Z)-2-cyano-3-(5-(1-cyclohexyl-1,6-dihydroimidaz...)copy SMILEScopy InChI
Affinity DataIC50: 0.127nMAssay Description:A commercial assay by Reaction Biology Corp.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8S22PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50274586(CHEMBL4128181)copy SMILEScopy InChI
Affinity DataIC50: 0.130nMAssay Description:Inhibition of human JAK3 using GEEEEYFELVKKKK as substrate in presence of 10 uM [gamma33P]ATP by radiometric methodMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM202554((E/Z)-2-cyano-N,N-dimethyl-3-(5-(1-((1S,2R)-2-meth...)copy SMILES
Affinity DataIC50: 0.154nMAssay Description:A commercial assay by Reaction Biology Corp.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8S22PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50274605(CHEMBL4128266)copy SMILEScopy InChI
Affinity DataIC50: 0.210nMAssay Description:Inhibition of human JAK3 using GEEEEYFELVKKKK as substrate in presence of 10 uM [gamma33P]ATP by radiometric methodMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 0.290nMAssay Description:Inhibition of human JAK3 using GEEEEYFELVKKKK as substrate in presence of 10 uM [gamma33P]ATP by radiometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6988PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 0.292nMAssay Description:A commercial assay by Reaction Biology Corp.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8S22PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50274584(CHEMBL4125719)copy SMILEScopy InChI
Affinity DataIC50: 0.390nMAssay Description:Inhibition of human JAK3 using GEEEEYFELVKKKK as substrate in presence of 10 uM [gamma33P]ATP by radiometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6988PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 0.496nMAssay Description:A commercial assay by Reaction Biology Corp.More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human JAK1 using poly[Glu:Tyr] (4:1) as substrate in presence of 10 uM [gamma33P]ATP by radiometric methodMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50274583(CHEMBL4125861)copy SMILEScopy InChI
Affinity DataIC50: 0.740nMAssay Description:Inhibition of human JAK3 using GEEEEYFELVKKKK as substrate in presence of 10 uM [gamma33P]ATP by radiometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6988PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50335231(3-{5-[4-(2-Hydroxy-2-methyl-propionyl)-piperazin-1...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human JAK3 using GEEEEYFELVKKKK as substrate in presence of 10 uM [gamma33P]ATP by radiometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6988PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Eberhard Karls University T£bingen

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human JAK2 using poly[Glu:Tyr] (4:1) as substrate in presence of 10 uM [gamma33P]ATP by radiometric methodMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50274586(CHEMBL4128181)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human JAK3 using GEEEEYFELVKKKK as substrate in presence of 200 uM [gamma33P]ATP by radiometric methodMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Eberhard Karls University T£bingen

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:A commercial assay by Reaction Biology Corp.More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibition of recombinant human JAK3 (781 to 1124 residues) expressed in baculovirus expression system assessed as reduction in polypeptide substrate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6988PubMed
TargetTyrosine-protein kinase JAK3 [781-1124](Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:In this ELISA-based kinase activity assay, a 96-well assay plate is coated with an artificial polypeptide serving as kinase substrate that contains t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8S22PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50274584(CHEMBL4125719)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human JAK1 using poly[Glu:Tyr] (4:1) as substrate in presence of 10 uM [gamma33P]ATP by radiometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6988PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50274584(CHEMBL4125719)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human JAK3 (781 to 1124 residues) expressed in baculovirus expression system assessed as reduction in polypeptide substrate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6988PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 8.90nMAssay Description:A commercial assay by Reaction Biology Corp.More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human TYK2 using KKSRGDYMTMQIG as substrate in presence of 10 uM [gamma33P]ATP by radiometric methodMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50274586(CHEMBL4128181)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human JAK3 (781 to 1124 residues) expressed in baculovirus expression system assessed as reduction in polypeptide substrate...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3 [781-1124](Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM202553((E/Z)-2-cyano-3-(5-(1-cyclohexyl-1,6-dihydroimidaz...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:In this ELISA-based kinase activity assay, a 96-well assay plate is coated with an artificial polypeptide serving as kinase substrate that contains t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8S22PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50274601(CHEMBL4127590)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human JAK3 using GEEEEYFELVKKKK as substrate in presence of 10 uM [gamma33P]ATP by radiometric methodMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50335231(3-{5-[4-(2-Hydroxy-2-methyl-propionyl)-piperazin-1...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human JAK3 (781 to 1124 residues) expressed in baculovirus expression system assessed as reduction in polypeptide substrate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6988PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50274637(CHEMBL4127091)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human JAK3 (781 to 1124 residues) expressed in baculovirus expression system assessed as reduction in polypeptide substrate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6988PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50274605(CHEMBL4128266)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human JAK1 using poly[Glu:Tyr] (4:1) as substrate in presence of 10 uM [gamma33P]ATP by radiometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6988PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50274583(CHEMBL4125861)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human JAK3 (781 to 1124 residues) expressed in baculovirus expression system assessed as reduction in polypeptide substrate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6988PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50274584(CHEMBL4125719)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human TYK2 using KKSRGDYMTMQIG as substrate in presence of 10 uM [gamma33P]ATP by radiometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6988PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50274601(CHEMBL4127590)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human JAK1 using poly[Glu:Tyr] (4:1) as substrate in presence of 10 uM [gamma33P]ATP by radiometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6988PubMed
TargetTyrosine-protein kinase JAK3 [781-1124](Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM202554((E/Z)-2-cyano-N,N-dimethyl-3-(5-(1-((1S,2R)-2-meth...)copy SMILES
Affinity DataIC50: 17nMAssay Description:In this ELISA-based kinase activity assay, a 96-well assay plate is coated with an artificial polypeptide serving as kinase substrate that contains t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8S22PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM202552((E)-3-(5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]py...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:A commercial assay by Reaction Biology Corp.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8S22PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM202552((E)-3-(5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]py...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human JAK1 using poly[Glu:Tyr] (4:1) as substrate in presence of 10 uM [gamma33P]ATP by radiometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6988PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM202552((E)-3-(5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]py...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of human JAK3 using GEEEEYFELVKKKK as substrate in presence of 10 uM [gamma33P]ATP by radiometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6988PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM202552((E)-3-(5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]py...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:A commercial assay by Reaction Biology Corp.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8S22PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50274602(CHEMBL4128324)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human JAK3 (781 to 1124 residues) expressed in baculovirus expression system assessed as reduction in polypeptide substrate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6988PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50274601(CHEMBL4127590)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of human TYK2 using KKSRGDYMTMQIG as substrate in presence of 10 uM [gamma33P]ATP by radiometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6988PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50274605(CHEMBL4128266)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant human JAK3 (781 to 1124 residues) expressed in baculovirus expression system assessed as reduction in polypeptide substrate...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50274615(CHEMBL4126944)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human JAK3 (781 to 1124 residues) expressed in baculovirus expression system assessed as reduction in polypeptide substrate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6988PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50274605(CHEMBL4128266)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of human TYK2 using KKSRGDYMTMQIG as substrate in presence of 10 uM [gamma33P]ATP by radiometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6988PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50274604(CHEMBL4126514)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of human JAK1 using poly[Glu:Tyr] (4:1) as substrate in presence of 10 uM [gamma33P]ATP by radiometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6988PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Eberhard Karls University T£bingen

Curated by ChEMBL
LigandPNGBDBM50274601(CHEMBL4127590)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of human JAK2 using poly[Glu:Tyr] (4:1) as substrate in presence of 10 uM [gamma33P]ATP by radiometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6988PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50274604(CHEMBL4126514)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of human JAK3 using GEEEEYFELVKKKK as substrate in presence of 10 uM [gamma33P]ATP by radiometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6988PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM202552((E)-3-(5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]py...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of recombinant human JAK3 (781 to 1124 residues) expressed in baculovirus expression system assessed as reduction in polypeptide substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6988PubMed
TargetTyrosine-protein kinase JAK3 [781-1124](Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM202552((E)-3-(5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]py...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:In this ELISA-based kinase activity assay, a 96-well assay plate is coated with an artificial polypeptide serving as kinase substrate that contains t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8S22PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50274586(CHEMBL4128181)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of human JAK1 using poly[Glu:Tyr] (4:1) as substrate in presence of 10 uM [gamma33P]ATP by radiometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6988PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM202553((E/Z)-2-cyano-3-(5-(1-cyclohexyl-1,6-dihydroimidaz...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:A commercial assay by Reaction Biology Corp.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8S22PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Eberhard Karls University T£bingen

Curated by ChEMBL
LigandPNGBDBM50274605(CHEMBL4128266)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibition of human JAK2 using poly[Glu:Tyr] (4:1) as substrate in presence of 10 uM [gamma33P]ATP by radiometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6988PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50274622(CHEMBL4126097)copy SMILEScopy InChI
Affinity DataIC50: 59nMAssay Description:Inhibition of recombinant human JAK3 (781 to 1124 residues) expressed in baculovirus expression system assessed as reduction in polypeptide substrate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6988PubMed
TargetTyrosine-protein kinase JAK3 [781-1124](Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM50426731(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:In this ELISA-based kinase activity assay, a 96-well assay plate is coated with an artificial polypeptide serving as kinase substrate that contains t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8S22PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM202554((E/Z)-2-cyano-N,N-dimethyl-3-(5-(1-((1S,2R)-2-meth...)copy SMILES
Affinity DataIC50: 64nMAssay Description:A commercial assay by Reaction Biology Corp.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8S22PubMed
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