Compile Data Set for Download or QSAR
Found 804 with Last Name = 'kouznetsova' and Initial = 'j'
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250655(CHEMBL4059985 | US10961200, Compound 189 | US11247...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250655(CHEMBL4059985 | US10961200, Compound 189 | US11247...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250655(CHEMBL4059985 | US10961200, Compound 189 | US11247...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Binding affinity to human His-tagged LDHA in presence of NADH by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM197160(GNE-140 (6))copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human LDHA using sodium pyruvate as substrate in presence of NAPDHMore data for this Ligand-Target Pair
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50445521(CHEMBL3103033 | US11345702, Table 1.21 | US2023039...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8N6HPubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250653(CHEMBL4090677 | US10961200, Compound 46 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM30884(1-(3-methylphenyl)-5-(piperidin-1-ylcarbonyl)-1H-b...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8N6HPubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250653(CHEMBL4090677 | US10961200, Compound 46 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Binding affinity to human His-tagged LDHA in presence of NADH by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50445520(CHEMBL3103034)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8N6HPubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50445516(CHEMBL3103038)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8N6HPubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50445514(CHEMBL3103040 | US11345702, Table 1.33 | US2023039...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8N6HPubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250653(CHEMBL4090677 | US10961200, Compound 46 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250677(CHEMBL4100845 | US10961200, Compound 52 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50445537(CHEMBL3103018)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8N6HPubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50445523(CHEMBL3103032)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8N6HPubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50445515(CHEMBL3103039)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8N6HPubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50445562(CHEMBL3102994)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8N6HPubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250656(CHEMBL4081890 | US11247971, Cmpd ID 276)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50445522(CHEMBL3102860)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8N6HPubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250677(CHEMBL4100845 | US10961200, Compound 52 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250677(CHEMBL4100845 | US10961200, Compound 52 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and EDTA by diaphorase/resazurin based fluorescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250656(CHEMBL4081890 | US11247971, Cmpd ID 276)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba...More data for this Ligand-Target Pair
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250656(CHEMBL4081890 | US11247971, Cmpd ID 276)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and EDTA by diaphorase/resazurin based fluorescen...More data for this Ligand-Target Pair
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50445511(CHEMBL3103043)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8N6HPubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50445555(CHEMBL3103000)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8N6HPubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50445561(CHEMBL3102995)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8N6HPubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50103568(CHEMBL3335794)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250648(CHEMBL4080497 | US10961200, Compound 20 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and EDTA by diaphorase/resazurin based fluorescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50445549(CHEMBL3103006)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8N6HPubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50445560(CHEMBL3102996)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8N6HPubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50103568(CHEMBL3335794)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and EDTA by diaphorase/resazurin based fluorescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250648(CHEMBL4080497 | US10961200, Compound 20 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250689(CHEMBL4069726 | US10961200, Compound 47 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Binding affinity to human His-tagged LDHA in presence of NADH by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50445519(CHEMBL3103035)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8N6HPubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50445557(CHEMBL3102998)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8N6HPubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50445559(CHEMBL3102997)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8N6HPubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50445535(CHEMBL3103020)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8N6HPubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250648(CHEMBL4080497 | US10961200, Compound 20 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50347949(CHEMBL599406 | US8637558, 46)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of PGDH (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8N6HPubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250652(CHEMBL4101800 | US10961200, Compound 42 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250652(CHEMBL4101800 | US10961200, Compound 42 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Binding affinity to human His-tagged LDHA in presence of NADH by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50445563(CHEMBL1408258)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8N6HPubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50445512(CHEMBL3103042)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8N6HPubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250649(CHEMBL4076027 | US10961200, Compound 51 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Binding affinity to human His-tagged LDHA in presence of NADH by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250649(CHEMBL4076027 | US10961200, Compound 51 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250649(CHEMBL4076027 | US10961200, Compound 51 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and EDTA by diaphorase/resazurin based fluorescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250652(CHEMBL4101800 | US10961200, Compound 42 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250667(CHEMBL4075666 | US10961200, Compound 40 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Binding affinity to human His-tagged LDHA in presence of NADH by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250667(CHEMBL4075666 | US10961200, Compound 40 | US112479...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250691(CHEMBL4062709 | US10961200, Compound 166 | US11247...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Binding affinity to human His-tagged LDHA in presence of NADH by SPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5J28PubMed
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