Affinity DataIC50: 1.40nMAssay Description:Inhibition of LFA1 by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Antagonist activity at human CXCR3 assessed as inhibition of ITAC-induced calcium mobilizationMore data for this Ligand-Target Pair
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Sunesis Pharmaceuticals, Inc.
Curated by ChEMBL
Sunesis Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of IP10-induced CXCR3 mediated cell migrationMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
Affinity DataIC50: 8.20nMAssay Description:Displacement of [125I] ITAC from the CXCR3 receptorMore data for this Ligand-Target Pair
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Sunesis Pharmaceuticals, Inc.
Curated by ChEMBL
Sunesis Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Sunesis Pharmaceuticals, Inc.
Curated by ChEMBL
Sunesis Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Sunesis Pharmaceuticals, Inc.
Curated by ChEMBL
Sunesis Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of ITAC-induced CXCR3 mediated cell migrationMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Sunesis Pharmaceuticals, Inc.
Curated by ChEMBL
Sunesis Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Sunesis Pharmaceuticals, Inc.
Curated by ChEMBL
Sunesis Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Sunesis Pharmaceuticals, Inc.
Curated by ChEMBL
Sunesis Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of MIG-induced CXCR3 mediated cell migrationMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Sunesis Pharmaceuticals, Inc.
Curated by ChEMBL
Sunesis Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Sunesis Pharmaceuticals, Inc.
Curated by ChEMBL
Sunesis Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Sunesis Pharmaceuticals, Inc.
Curated by ChEMBL
Sunesis Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 66nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 69nMAssay Description:Inhibition of LFA1-mediated Staphylococcal enterotoxin B-stimulated human T cell activation in presence of 10% fetal bovine serumMore data for this Ligand-Target Pair
Affinity DataIC50: 73nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Sunesis Pharmaceuticals, Inc.
Curated by ChEMBL
Sunesis Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 88nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Sunesis Pharmaceuticals, Inc.
Curated by ChEMBL
Sunesis Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
Affinity DataIC50: 144nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
Affinity DataIC50: 146nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
Affinity DataIC50: 154nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
Affinity DataIC50: 156nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of LFA1-mediated Staphylococcal enterotoxin B-stimulated human T cell activation in presence of 10% fetal bovine serumMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of LFA1-mediated Staphylococcal enterotoxin B-stimulated human T cell activation in presence of 10% fetal bovine serumMore data for this Ligand-Target Pair
Affinity DataIC50: 299nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
Affinity DataIC50: 375nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Inhibition of LFA1-mediated Staphylococcal enterotoxin B-stimulated human T cell activation in presence of 10% fetal bovine serumMore data for this Ligand-Target Pair
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