Compile Data Set for Download or QSAR
Found 84 with Last Name = 'kumer' and Initial = 'j'
TargetIntegrin alpha-L(Homo sapiens (Human))
Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50324826((2S)-2-(2,6-dichloro-4-(3-hydroxy-3-(3-hydroxyphen...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of LFA1 by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58MKBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211148((R)-N-(1-(4-oxo-3-(4-(prop-1-ynyl)phenyl)-3,4-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1SXNPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211114((-)-(R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Antagonist activity at human CXCR3 assessed as inhibition of ITAC-induced calcium mobilizationMore data for this Ligand-Target Pair
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50324824((S)-2-(2-(benzofuran-2-carbonyl)-5,7-dichloro-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58MKBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211130((R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydroquin...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1SXNPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211138((R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydroquin...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1SXNPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211137((R)-N-(1-(3-(4-nitrophenyl)-4-oxo-3,4-dihydroquina...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1SXNPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211114((-)-(R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of IP10-induced CXCR3 mediated cell migrationMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211114((-)-(R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211114((-)-(R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 8.20nMAssay Description:Displacement of [125I] ITAC from the CXCR3 receptorMore data for this Ligand-Target Pair
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50324822((S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58MKBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211128(2-biphenyl-4-yl-N-(2-ethoxy-ethyl)-N-{(R)-1-[3-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1SXNPubMed
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50324810((S)-2-(5,7-dichloro-2-(4-methylbenzoyl)-1,2,3,4-te...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58MKBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211121((R)-N-(1-(3-(4-cyanophenyl)-4-oxo-3,4-dihydroquina...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1SXNPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211123((R)-N-(1-(3-(4-fluorophenyl)-4-oxo-3,4-dihydroquin...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1SXNPubMed
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50324823((S)-2-(5,7-dichloro-2-(2,3-dihydrobenzofuran-6-car...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58MKBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211123((R)-N-(1-(3-(4-fluorophenyl)-4-oxo-3,4-dihydroquin...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1SXNPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211143((R)-N-(1-(3-(4-methoxyphenyl)-4-oxo-3,4-dihydroqui...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1SXNPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211114((-)-(R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of ITAC-induced CXCR3 mediated cell migrationMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211122((R)-N-(1-(3-(4-chlorophenyl)-4-oxo-3,4-dihydroquin...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1SXNPubMed
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50324812((S)-2-(5,7-dichloro-2-(4-chlorobenzoyl)-1,2,3,4-te...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58MKBPubMed
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50324806((S,E)-2-(5,7-dichloro-2-(3-(furan-2-yl)acryloyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58MKBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211115((R)-N-(1-(4-oxo-3-p-tolyl-3,4-dihydroquinazolin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1SXNPubMed
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50324816((S)-3-benzamido-2-(5,7-dichloro-2-(4-chlorobenzoyl...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58MKBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211114((-)-(R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of MIG-induced CXCR3 mediated cell migrationMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211119((R)-N-(2-ethoxyethyl)-N-(1-(3-(4-fluorophenyl)-4-o...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1SXNPubMed
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50092956(1-(4-Acetyl-piperazin-1-yl)-3-[4-(2-isopropyl-phen...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58MKBPubMed
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50324817((S)-2-(5,7-dichloro-2-(4-chlorobenzoyl)-1,2,3,4-te...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58MKBPubMed
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50324811((S)-2-(5,7-dichloro-2-(3-chlorobenzoyl)-1,2,3,4-te...)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58MKBPubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50324824((S)-2-(2-(benzofuran-2-carbonyl)-5,7-dichloro-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Inhibition of LFA1-mediated Staphylococcal enterotoxin B-stimulated human T cell activation in presence of 10% fetal bovine serumMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58MKBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211118((R)-N-(1-(3-(4-fluorophenyl)-4-oxo-3,4-dihydroquin...)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1SXNPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211156(2-biphenyl-4-yl-N-(2-dimethylamino-ethyl)-N-{(R)-1...)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1SXNPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211132(2-biphenyl-4-yl-N-(2-ethoxy-ethyl)-N-{(R)-1-[3-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1SXNPubMed
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50324807((S)-2-(2-benzoyl-5,7-dichloro-1,2,3,4-tetrahydrois...)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58MKBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211117((R)-N-(2-(dimethylamino)ethyl)-N-(1-(3-(4-fluoroph...)copy SMILEScopy InChI
Affinity DataIC50: 88nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1SXNPubMed
TargetIntegrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50324809((S)-2-(5,7-dichloro-2-(3-methylbenzoyl)-1,2,3,4-te...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of LFA1/ICAM1 interaction in human Hut-78 cells by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58MKBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211129((R)-N-(1-(3-(4-fluorophenyl)-4-oxo-3,4-dihydroquin...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1SXNPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211152((R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydropyri...)copy SMILEScopy InChI
Affinity DataIC50: 144nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1SXNPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211140((R)-N-(2-(dimethylamino)ethyl)-N-(1-(3-(4-fluoroph...)copy SMILEScopy InChI
Affinity DataIC50: 146nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1SXNPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211151((R)-N-(2-(dimethylamino)ethyl)-N-(1-(3-(4-fluoroph...)copy SMILEScopy InChI
Affinity DataIC50: 154nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1SXNPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211150((R)-N-(2-(dimethylamino)ethyl)-N-(1-(3-(4-fluoroph...)copy SMILEScopy InChI
Affinity DataIC50: 156nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1SXNPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211145((R)-N-(2-(1H-imidazol-2-yl)-2-oxoethyl)-N-(1-(3-(4...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1SXNPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211144((R)-N-(1-(3-(4-fluorophenyl)-4-oxo-3,4-dihydroquin...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1SXNPubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50324811((S)-2-(5,7-dichloro-2-(3-chlorobenzoyl)-1,2,3,4-te...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of LFA1-mediated Staphylococcal enterotoxin B-stimulated human T cell activation in presence of 10% fetal bovine serumMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58MKBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50167778(CHEMBL194494 | Decanoic acid (2-dimethylamino-ethy...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1SXNPubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50324822((S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of LFA1-mediated Staphylococcal enterotoxin B-stimulated human T cell activation in presence of 10% fetal bovine serumMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58MKBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211142((R)-N-(1-(4-oxo-3-phenyl-3,4-dihydroquinazolin-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 299nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1SXNPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211157((R)-N-(1-(3-(4-fluorophenyl)-4-oxo-3,4-dihydroquin...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1SXNPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211155((R)-N-(2-(dimethylamino)ethyl)-N-(1-(3-(4-fluoroph...)copy SMILEScopy InChI
Affinity DataIC50: 375nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1SXNPubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50324812((S)-2-(5,7-dichloro-2-(4-chlorobenzoyl)-1,2,3,4-te...)copy SMILEScopy InChI
Affinity DataIC50: 430nMAssay Description:Inhibition of LFA1-mediated Staphylococcal enterotoxin B-stimulated human T cell activation in presence of 10% fetal bovine serumMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58MKBPubMed
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