Compile Data Set for Download or QSAR
Found 2637 with Last Name = 'lefranc' and Initial = 'j'
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50520160(CHEMBL4515413 | US10894784, Example 01.03)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged FLT3 (564 to end residues) expressed in sf21 cells using biotin labelled Ahx-GGEEEEYFELVKKKK pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7795PubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM478724(US10894784, Example 117.02 | cyclopropyl(4-{(1R or...)copy SMILES
Affinity DataIC50: 0.330nMAssay Description:Recombinant full-length N-terminally His-tagged human TBK1, expressed in insect cells and purified by Ni-NTA affinity chromatography, was purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6PFTUS Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM478844(US10894784, Example 117.05)copy SMILES
Affinity DataIC50: 0.473nMAssay Description:Recombinant full-length N-terminally His-tagged human TBK1, expressed in insect cells and purified by Ni-NTA affinity chromatography, was purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6PFTUS Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM478804(US10894784, Example 152.02)copy SMILEScopy InChI
Affinity DataIC50: 0.480nMAssay Description:Recombinant full-length N-terminally His-tagged human TBK1, expressed in insect cells and purified by Ni-NTA affinity chromatography, was purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6PFTUS Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM478725(3,3,3-trifluoro-1-(4-{(1R or 1S)-1-[2-({6-[6-(pyrr...)copy SMILES
Affinity DataIC50: 0.490nMAssay Description:Recombinant full-length N-terminally His-tagged human TBK1, expressed in insect cells and purified by Ni-NTA affinity chromatography, was purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6PFTUS Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM478853(US10894784, Example 164.03)copy SMILES
Affinity DataIC50: 0.558nMAssay Description:Recombinant full-length N-terminally His-tagged human TBK1, expressed in insect cells and purified by Ni-NTA affinity chromatography, was purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6PFTUS Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM478542(US10894784, Example 55.03 | cyclopropyl{4-[(1R or ...)copy SMILES
Affinity DataIC50: 0.564nMAssay Description:Recombinant full-length N-terminally His-tagged human TBK1, expressed in insect cells and purified by Ni-NTA affinity chromatography, was purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6PFTUS Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM478855(US10894784, Example 164.05)copy SMILES
Affinity DataIC50: 0.566nMAssay Description:Recombinant full-length N-terminally His-tagged human TBK1, expressed in insect cells and purified by Ni-NTA affinity chromatography, was purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6PFTUS Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM478573(US10894784, Example 55.03.01 | US10894784, Example...)copy SMILES
Affinity DataIC50: 0.610nMAssay Description:Recombinant full-length N-terminally His-tagged human TBK1, expressed in insect cells and purified by Ni-NTA affinity chromatography, was purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6PFTUS Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM478719((4-{(1R or 1S)-1-[2-({6-[6-(azetidin-1-yl)pyrimidi...)copy SMILES
Affinity DataIC50: 0.620nMAssay Description:Recombinant full-length N-terminally His-tagged human TBK1, expressed in insect cells and purified by Ni-NTA affinity chromatography, was purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6PFTUS Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM478581(1-{4-[(1R or 1S)-1-{2-[(6-{1-[(1-chlorocyclopropyl...)copy SMILES
Affinity DataIC50: 0.640nMAssay Description:Recombinant full-length N-terminally His-tagged human TBK1, expressed in insect cells and purified by Ni-NTA affinity chromatography, was purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6PFTUS Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM478573(US10894784, Example 55.03.01 | US10894784, Example...)copy SMILES
Affinity DataIC50: 0.660nMAssay Description:Recombinant full-length N-terminally His-tagged human TBK1, expressed in insect cells and purified by Ni-NTA affinity chromatography, was purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6PFTUS Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM50520150(CHEMBL4566796)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of recombinant full length human N-terminal His-tagged TBK1 using biotin-labelled Ahx-GDEDFSSFAEPG peptide as substrate preincubated with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7795PubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM478614(3,3,3-trifluoro-1-(4-{(1R or 1S)-1-[2-({6-[6-(meth...)copy SMILES
Affinity DataIC50: 0.700nMAssay Description:Recombinant full-length N-terminally His-tagged human TBK1, expressed in insect cells and purified by Ni-NTA affinity chromatography, was purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6PFTUS Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM478571(1-{4-[(1R or 1S)-1-(2-{[6-(1-{[(1R or IS)-2,2-difl...)copy SMILES
Affinity DataIC50: 0.720nMAssay Description:Recombinant full-length N-terminally His-tagged human TBK1, expressed in insect cells and purified by Ni-NTA affinity chromatography, was purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6PFTUS Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM478583(US10894784, Example 70.02 | {4-[(1R or 1S)-1-(2-{[...)copy SMILES
Affinity DataIC50: 0.730nMAssay Description:Recombinant full-length N-terminally His-tagged human TBK1, expressed in insect cells and purified by Ni-NTA affinity chromatography, was purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6PFTUS Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM478718(1-(4-{(1R or 1S)-1-[2-({6-[6-(azetidin-1-yl)pyrimi...)copy SMILES
Affinity DataIC50: 0.760nMAssay Description:Recombinant full-length N-terminally His-tagged human TBK1, expressed in insect cells and purified by Ni-NTA affinity chromatography, was purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6PFTUS Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM478720(US10894784, Example 116.02 | cyclopropyl(4-{(1R or...)copy SMILES
Affinity DataIC50: 0.760nMAssay Description:Recombinant full-length N-terminally His-tagged human TBK1, expressed in insect cells and purified by Ni-NTA affinity chromatography, was purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6PFTUS Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM478843(US10894784, Example 117.04)copy SMILES
Affinity DataIC50: 0.819nMAssay Description:Recombinant full-length N-terminally His-tagged human TBK1, expressed in insect cells and purified by Ni-NTA affinity chromatography, was purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6PFTUS Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM478854(US10894784, Example 164.04)copy SMILES
Affinity DataIC50: 0.832nMAssay Description:Recombinant full-length N-terminally His-tagged human TBK1, expressed in insect cells and purified by Ni-NTA affinity chromatography, was purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6PFTUS Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM478845(US10894784, Example 117.06)copy SMILES
Affinity DataIC50: 0.860nMAssay Description:Recombinant full-length N-terminally His-tagged human TBK1, expressed in insect cells and purified by Ni-NTA affinity chromatography, was purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6PFTUS Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM478594((4-{(1R or 1S)-1-[2-({7-chloro-6-[1-(cyclobutylmet...)copy SMILES
Affinity DataIC50: 0.880nMAssay Description:Recombinant full-length N-terminally His-tagged human TBK1, expressed in insect cells and purified by Ni-NTA affinity chromatography, was purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6PFTUS Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM478582(1-{4-[(1R or 1S)-1-(2-{[7-chloro-6-(1-{[(1RS)-2,2-...)copy SMILES
Affinity DataIC50: 0.880nMAssay Description:Recombinant full-length N-terminally His-tagged human TBK1, expressed in insect cells and purified by Ni-NTA affinity chromatography, was purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6PFTUS Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM478852(US10894784, Example 164.02)copy SMILES
Affinity DataIC50: 0.943nMAssay Description:Recombinant full-length N-terminally His-tagged human TBK1, expressed in insect cells and purified by Ni-NTA affinity chromatography, was purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6PFTUS Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM478805(US10894784, Example 152.03)copy SMILEScopy InChI
Affinity DataIC50: 0.960nMAssay Description:Recombinant full-length N-terminally His-tagged human TBK1, expressed in insect cells and purified by Ni-NTA affinity chromatography, was purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6PFTUS Patent
TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM420259(US10487092, Example 107 | [(3S)-3-(Dimethylamino)p...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3GPZUS Patent
TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM420251((7S)—N-[3-(Dimethylamino)propyl]-4-[(6-methoxypyra...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3GPZUS Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM478708((4-{(1R or 1S)-1-[2-({6-[6-(azetidin-1-yl)-5-metho...)copy SMILES
Affinity DataIC50: 1nMAssay Description:Recombinant full-length N-terminally His-tagged human TBK1, expressed in insect cells and purified by Ni-NTA affinity chromatography, was purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6PFTUS Patent
TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM420271((7S)—N,N-Bis(2-methoxyethyl)-4-[(6-methoxypyrazolo...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3GPZUS Patent
TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM420250(1-((7S)-4-[(6-Methoxypyrazolo[1,5-a]pyridin-5-yl)a...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3GPZUS Patent
TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM420249((7S)—N-Butyl-4-[(6-methoxypyrazolo[1,5-a]pyridin-5...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3GPZUS Patent
TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM420246((7S)—N-Ethyl-4-[(6-methoxypyrazolo[1,5-a]pyridin-5...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3GPZUS Patent
TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM420157((7S)-4-[(6-Chloropyrazolo[1,5-a]pyridin-5-yl)amino...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3GPZUS Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50520159(CHEMBL4543618)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged FLT3 (564 to end residues) expressed in sf21 cells using biotin labelled Ahx-GGEEEEYFELVKKKK pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7795PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Bayer AG

Curated by ChEMBL
LigandPNGBDBM50520175(CHEMBL4451595 | US10894784, Example 135.02)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged FLT3 (564 to end residues) expressed in sf21 cells using biotin labelled Ahx-GGEEEEYFELVKKKK pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7795PubMed
TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM420278((7S)-4-[(6-Methoxypyrazolo[1,5-a]pyridin-5-yl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3GPZUS Patent
TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM420277((7S)-4-[(6-Methoxypyrazolo[1,5-a]pyridin-5-yl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3GPZUS Patent
TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM420276((7S)-4-[(6-Methoxypyrazolo[1,5-a]pyridin-5-yl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3GPZUS Patent
TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM420274((7S)-4-[(6-Methoxypyrazolo[1,5-a]pyridin-5-yl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3GPZUS Patent
TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM420273((7S)-4-[(6-Methoxypyrazolo[1,5-a]pyridin-5-yl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3GPZUS Patent
TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM420270((7S)—N-Ethyl-N-(2-methoxyethyl)-4-[(6-methoxypyraz...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3GPZUS Patent
TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM420269((7S)—N-Ethyl-N-(2-hydroxyethyl)-4-[(6-methoxypyraz...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3GPZUS Patent
TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM420268((7S)-4-[(6-Methoxypyrazolo[1,5-a]pyridin-5-yl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3GPZUS Patent
TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM420267((7S)—N-[2-(Dimethylamino)ethyl]-N-ethyl-4-[(6-meth...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3GPZUS Patent
TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM420266(4-[2-(Dimethylamino)ethyl]piperazin-1-yl(7S)-4-[(6...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3GPZUS Patent
TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM420265((7S)-4-[(6-Methoxypyrazolo[1,5-a]pyridin-5-yl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3GPZUS Patent
TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM420262((4-[2-Dimethylamino)ethyl]methyl)aminopiperidin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3GPZUS Patent
TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM420261(US10487092, Example 109 | [4-(Dimethylamino)piperi...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3GPZUS Patent
TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM420260(US10487092, Example 108 | [(3S,4S)-3,4-Dihydroxypy...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3GPZUS Patent
TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM420258(US10487092, Example 106 | [(3R)-3-(Dimethylamino)p...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3GPZUS Patent
Displayed 1 to 50 (of 2637 total ) | Next | Last >>
Jump to: