Compile Data Set for Download or QSAR
Found 116 with Last Name = 'mclaren' and Initial = 'j'
TargetSerine protease 1(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072292((3S,3aS,6aS)-3-Phenylsulfanyl-hexahydro-cyclopenta...)copy SMILEScopy InChI
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetSerine protease 1(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072285((3R,3aS,6aS)-3-Phenylsulfanyl-hexahydro-cyclopenta...)copy SMILEScopy InChI
Affinity DataIC50: 0.120nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetSerine protease 1(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072289((3S,3aR,6aS)-3-(4-Methyl-2-oxo-pent-3-enyl)-hexahy...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetSerine protease 1(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072283((3S,3aR,6aS)-3-Benzyl-hexahydro-cyclopenta[b]furan...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetSerine protease 1(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072286((3R,3aR,6aS)-3-Benzyl-hexahydro-cyclopenta[b]furan...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetProthrombin(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072284((1S,2R,4aR,6aS,6bS,7R,9aS,10aS)-2-Acetoxy-1,4a,6a,...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetProthrombin(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072285((3R,3aS,6aS)-3-Phenylsulfanyl-hexahydro-cyclopenta...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetChymotrypsin-C(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072290((3S,3aR,6aS)-3-Allyl-hexahydro-cyclopenta[b]furan-...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetProthrombin(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50075121(5-[(3aS,8aS)-5-(4-Hydroxy-phenyl)-2-oxo-3,3a,8,8a-...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibitory activity of the compound against human thrombin was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KS3PubMed
TargetProthrombin(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072292((3S,3aS,6aS)-3-Phenylsulfanyl-hexahydro-cyclopenta...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
University of Washington

Curated by ChEMBL
LigandPNGBDBM50018011(Aubagio | CHEBI:68540 | HMR-1726 | TERIFLUNOMIDE)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of C-terminal His6-tagged rat DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072287((3S,6aS)-3-(4-Methyl-2-oxo-pent-3-enyl)-hexahydro-...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetProthrombin(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072289((3S,3aR,6aS)-3-(4-Methyl-2-oxo-pent-3-enyl)-hexahy...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetSerine protease 1(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072290((3S,3aR,6aS)-3-Allyl-hexahydro-cyclopenta[b]furan-...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetSerine protease 1(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072287((3S,6aS)-3-(4-Methyl-2-oxo-pent-3-enyl)-hexahydro-...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetChymotrypsin-C(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072282((3R,3aR,6aS)-3-Allyl-hexahydro-cyclopenta[b]furan-...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetSerine protease 1(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072293(5-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetSerine protease 1(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072282((3R,3aR,6aS)-3-Allyl-hexahydro-cyclopenta[b]furan-...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetProthrombin(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072282((3R,3aR,6aS)-3-Allyl-hexahydro-cyclopenta[b]furan-...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetChymotrypsin-C(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072284((1S,2R,4aR,6aS,6bS,7R,9aS,10aS)-2-Acetoxy-1,4a,6a,...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetSerine protease 1(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072284((1S,2R,4aR,6aS,6bS,7R,9aS,10aS)-2-Acetoxy-1,4a,6a,...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Compound was evaluated for the inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetProthrombin(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072283((3S,3aR,6aS)-3-Benzyl-hexahydro-cyclopenta[b]furan...)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetProthrombin(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50075122(5-((3aS,8aS)-2-Oxo-3,3a,8,8a-tetrahydro-2H-indeno[...)copy SMILEScopy InChI
Affinity DataIC50: 77nMAssay Description:Inhibitory activity of the compound against human thrombin was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KS3PubMed
TargetProthrombin(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072286((3R,3aR,6aS)-3-Benzyl-hexahydro-cyclopenta[b]furan...)copy SMILEScopy InChI
Affinity DataIC50: 92nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetProthrombin(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072290((3S,3aR,6aS)-3-Allyl-hexahydro-cyclopenta[b]furan-...)copy SMILEScopy InChI
Affinity DataIC50: 98nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetChymotrypsin-C(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072292((3S,3aS,6aS)-3-Phenylsulfanyl-hexahydro-cyclopenta...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetChymotrypsin-C(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072289((3S,3aR,6aS)-3-(4-Methyl-2-oxo-pent-3-enyl)-hexahy...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetChymotrypsin-C(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072286((3R,3aR,6aS)-3-Benzyl-hexahydro-cyclopenta[b]furan...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetChymotrypsin-C(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072283((3S,3aR,6aS)-3-Benzyl-hexahydro-cyclopenta[b]furan...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetChymotrypsin-C(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072285((3R,3aS,6aS)-3-Phenylsulfanyl-hexahydro-cyclopenta...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Mus musculus)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50018011(Aubagio | CHEBI:68540 | HMR-1726 | TERIFLUNOMIDE)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of C-terminal His6-tagged mouse DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072293(5-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibitory activity of the compound against human thrombin was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KS3PubMed
TargetProthrombin(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072293(5-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetSerine protease 1(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072291(4-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Washington

Curated by ChEMBL
LigandPNGBDBM50018011(Aubagio | CHEBI:68540 | HMR-1726 | TERIFLUNOMIDE)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50075123(4-((3R,3aS,8aS)-2-Oxo-3,3a,8,8a-tetrahydro-2H-inde...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibitory activity of the compound against human thrombin was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KS3PubMed
TargetProthrombin(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50075120(5-[(3R,3aS,8aS)-5-(4-Hydroxy-phenyl)-2-oxo-3,3a,8,...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory activity of the compound against human thrombin was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KS3PubMed
TargetProthrombin(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50075119(5-[(3aR,8aS)-6-(3-Methoxy-phenyl)-3-methyl-2-oxo-3...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory activity of the compound against human thrombin was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KS3PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Mus musculus)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50365230(CHEMBL1956285 | US11903936, Compound DSM265 | US92...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of C-terminal His6-tagged mouse DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D6ZPubMed
TargetSerine protease 1(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072288(3-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
University of Washington

Curated by ChEMBL
LigandPNGBDBM50365230(CHEMBL1956285 | US11903936, Compound DSM265 | US92...)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of C-terminal His6-tagged rat DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D6ZPubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
University of Washington

Curated by ChEMBL
LigandPNGBDBM50538344(CHEMBL4633246)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes using midazolam as substrate preincubated for 30 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D6ZPubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
University of Washington

Curated by ChEMBL
LigandPNGBDBM50538344(CHEMBL4633246)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes using testosterone as substrate preincubated for 30 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D6ZPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072284((1S,2R,4aR,6aS,6bS,7R,9aS,10aS)-2-Acetoxy-1,4a,6a,...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was evaluated for the inhibition of human leukocyte elastase(HLE).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetProthrombin(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072291(4-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)copy SMILEScopy InChI
Affinity DataIC50: 1.68E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoWellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50072284((1S,2R,4aR,6aS,6bS,7R,9aS,10aS)-2-Acetoxy-1,4a,6a,...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ105FPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University of Washington

Curated by ChEMBL
LigandPNGBDBM50538344(CHEMBL4633246)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate measured for 10 to 30 mins in presence of NADPH regenerating system by U...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D6ZPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University of Washington

Curated by ChEMBL
LigandPNGBDBM50538344(CHEMBL4633246)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using tolbutamide as substrate measured for 10 to 30 mins in presence of NADPH regenerating system by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D6ZPubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University of Washington

Curated by ChEMBL
LigandPNGBDBM50538344(CHEMBL4633246)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using (S)-mephenytoin as substrate measured for 10 to 30 mins in presence of NADPH regenerating syste...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D6ZPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University of Washington

Curated by ChEMBL
LigandPNGBDBM50538344(CHEMBL4633246)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate measured for 10 to 30 mins in presence of NADPH regenerating syste...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D6ZPubMed
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