Compile Data Set for Download or QSAR
Found 1949 with Last Name = 'niu' and Initial = 'j'
LigandPNGBDBM104963(CHEMBL507361 | US11147816, PD0325901 | US11701360,...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
LigandPNGBDBM50391802((3,4-difluoro-2-(2-fluoro-4-iodophenylamino)phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380930(CHEMBL2016890)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of p70S6K after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41MTPubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380931(CHEMBL2016886)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of p70S6K after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41MTPubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380935(CHEMBL2016887)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of p70S6K after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41MTPubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380929(CHEMBL2016892)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of p70S6K after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41MTPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380939(CHEMBL2016893)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of AKT1 after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41MTPubMed
LigandPNGBDBM50391804(CHEMBL2146893)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5P80PubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380932(CHEMBL2016771)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of p70S6K after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41MTPubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380934(CHEMBL2016885)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of p70S6K after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41MTPubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380936(CHEMBL2016888)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of p70S6K after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41MTPubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50379531(CHEMBL2012702)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of p70S6K after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41MTPubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380938(CHEMBL2016891)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of p70S6K after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41MTPubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380939(CHEMBL2016893)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of p70S6K after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41MTPubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50379530(CHEMBL2012701)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of p70S6K after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41MTPubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380937(CHEMBL2016889)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of p70S6K after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41MTPubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380933(CHEMBL2012699)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of p70S6K after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41MTPubMed
TargetHistone-lysine N-methyltransferase SETD2(Homo sapiens (Human))TBA
LigandPNGBDBM50582891(CHEMBL5078908)copy SMILES
Affinity DataIC50: 3nMAssay Description:Inhibition of SETD2 (unknown origin) preincubated for 30 mins followed by SAM substrate addition measured after 2 hrs by plate reader methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z03D29PubMed
LigandPNGBDBM50391805(CHEMBL2146894)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5P80PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380938(CHEMBL2016891)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of AKT1 after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41MTPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380929(CHEMBL2016892)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of AKT1 after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41MTPubMed
LigandPNGBDBM50391811(CHEMBL2146895)copy SMILEScopy InChI
Affinity DataIC50: 5.10nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5P80PubMed
LigandPNGBDBM50391800(CHEMBL2146898)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5P80PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380930(CHEMBL2016890)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of AKT1 after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41MTPubMed
LigandPNGBDBM50391803(CHEMBL2146888)copy SMILEScopy InChI
Affinity DataIC50: 6.60nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase SETD2(Homo sapiens (Human))TBA
LigandPNGBDBM50582889(CHEMBL5073608)copy SMILES
Affinity DataIC50: 7nMAssay Description:Inhibition of SETD2 (unknown origin) preincubated for 30 mins followed by SAM substrate addition measured after 2 hrs by plate reader methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z03D29PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380937(CHEMBL2016889)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of AKT1 after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41MTPubMed
LigandPNGBDBM50391801(CHEMBL2146892)copy SMILEScopy InChI
Affinity DataIC50: 7.20nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5P80PubMed
LigandPNGBDBM50391808(CHEMBL2146896)copy SMILEScopy InChI
Affinity DataIC50: 7.60nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5P80PubMed
TargetHistone-lysine N-methyltransferase SETD2(Homo sapiens (Human))TBA
LigandPNGBDBM50582885(CHEMBL5091591)copy SMILES
Affinity DataIC50: 8nMAssay Description:Inhibition of SETD2 (unknown origin) preincubated for 30 mins followed by SAM substrate addition measured after 2 hrs by plate reader methodMore data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380936(CHEMBL2016888)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of AKT1 after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41MTPubMed
TargetHistone-lysine N-methyltransferase SETD2(Homo sapiens (Human))TBA
LigandPNGBDBM50582892(CHEMBL5093241)copy SMILES
Affinity DataIC50: 8nMAssay Description:Inhibition of SETD2 (unknown origin) preincubated for 30 mins followed by SAM substrate addition measured after 2 hrs by plate reader methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z03D29PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380931(CHEMBL2016886)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of AKT1 after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41MTPubMed
TargetHistone-lysine N-methyltransferase SETD2(Homo sapiens (Human))TBA
LigandPNGBDBM50582878(CHEMBL5082544)copy SMILES
Affinity DataIC50: 12nMAssay Description:Inhibition of SETD2 (unknown origin) preincubated for 30 mins followed by SAM substrate addition measured after 2 hrs by plate reader methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z03D29PubMed
TargetHistone-lysine N-methyltransferase SETD2(Homo sapiens (Human))TBA
LigandPNGBDBM50582890(CHEMBL5094380)copy SMILES
Affinity DataIC50: 12nMAssay Description:Inhibition of SETD2 (unknown origin) preincubated for 30 mins followed by SAM substrate addition measured after 2 hrs by plate reader methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z03D29PubMed
TargetHistone-lysine N-methyltransferase SETD2(Homo sapiens (Human))TBA
LigandPNGBDBM50582883(CHEMBL5082960)copy SMILES
Affinity DataIC50: 12nMAssay Description:Inhibition of SETD2 (unknown origin) preincubated for 30 mins followed by SAM substrate addition measured after 2 hrs by plate reader methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z03D29PubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380930(CHEMBL2016890)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of p70S6K-mediated ribosomal protein S6 phosphorylation in human A549 cells after 3 hrs by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41MTPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380935(CHEMBL2016887)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of AKT1 after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41MTPubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380935(CHEMBL2016887)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of p70S6K-mediated ribosomal protein S6 phosphorylation in human A549 cells after 3 hrs by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41MTPubMed
TargetHistone-lysine N-methyltransferase SETD2(Homo sapiens (Human))TBA
LigandPNGBDBM50582880(CHEMBL5071957)copy SMILES
Affinity DataIC50: 15nMAssay Description:Inhibition of SETD2 (unknown origin) preincubated for 30 mins followed by SAM substrate addition measured after 2 hrs by plate reader methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z03D29PubMed
LigandPNGBDBM50391806(CHEMBL2146899)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5P80PubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM25737(12-[(adamantan-1-ylcarbamoyl)amino]dodecanoic acid...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human sEH expressed in insect High Five cells preincubated for 5 mins followed by addition of t-DPPO as substrate measured ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB18TZPubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380936(CHEMBL2016888)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of p70S6K-mediated ribosomal protein S6 phosphorylation in human A549 cells after 3 hrs by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41MTPubMed
TargetHistone-lysine N-methyltransferase SETD2(Homo sapiens (Human))TBA
LigandPNGBDBM50582893(CHEMBL5072597)copy SMILES
Affinity DataIC50: 17nMAssay Description:Inhibition of SETD2 (unknown origin) preincubated for 30 mins followed by SAM substrate addition measured after 2 hrs by plate reader methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z03D29PubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380929(CHEMBL2016892)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of p70S6K-mediated ribosomal protein S6 phosphorylation in human A549 cells after 3 hrs by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD41MTPubMed
TargetHistone-lysine N-methyltransferase SETD2(Homo sapiens (Human))TBA
LigandPNGBDBM50582894(CHEMBL5076615)copy SMILES
Affinity DataIC50: 18nMAssay Description:Inhibition of SETD2 (unknown origin) preincubated for 30 mins followed by SAM substrate addition measured after 2 hrs by plate reader methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM50391812(CHEMBL2146885)copy SMILEScopy InChI
Affinity DataIC50: 19.5nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5P80PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Exelixis Inc

Curated by ChEMBL
LigandPNGBDBM50486034(CHEMBL2204501)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Displacement of biotinylated geldanamycin from human His-tagged Hsp90 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68KKPubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Exelixis Inc

Curated by ChEMBL
LigandPNGBDBM50486035(CHEMBL2204498)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Displacement of biotinylated geldanamycin from human His-tagged Hsp90 by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68KKPubMed
TargetHistone-lysine N-methyltransferase SETD2(Homo sapiens (Human))TBA
LigandPNGBDBM50582885(CHEMBL5091591)copy SMILES
Affinity DataIC50: 23nMAssay Description:Inhibition of SETD2 in human A549 cells assessed as H3K36 trimethyl mark incubated for 3 days by in-cell western assayMore data for this Ligand-Target Pair
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