Compile Data Set for Download or QSAR
Found 218 with Last Name = 'piraino' and Initial = 'j'
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50040861((S)-2-(5-(((1,2-DIHYDRO-3-METHYL-1-OXOBENZO(F)QUIN...)copy SMILEScopy InChI
Affinity DataKi:  0.0900nMAssay Description:Inhibition of TS by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2GGPPubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50389112(CHEMBL2064556)copy SMILEScopy InChI
Affinity DataKi:  2.80nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ673WPubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50389111(CHEMBL2064555)copy SMILEScopy InChI
Affinity DataKi:  3.40nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ673WPubMed
LigandPNGBDBM34012(3-fluorophenylalanine derivative, 21b)copy SMILEScopy InChI
Affinity DataKi:  6nM ΔG°:  -45.4kJ/molepH: 7.5 T: 2°CAssay Description:The cis/trans conversion of cis-Suc-AEPFpNA peptide by the PPIase led to the cleavage of para nitroaniline by subtilisin which was monitored at 390 n...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD100HPubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50389111(CHEMBL2064555)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ673WPubMed
LigandPNGBDBM34011(3-fluorophenylalanine derivative, 21a)copy SMILEScopy InChI
Affinity DataKi:  8nM ΔG°:  -44.7kJ/molepH: 7.5 T: 2°CAssay Description:The cis/trans conversion of cis-Suc-AEPFpNA peptide by the PPIase led to the cleavage of para nitroaniline by subtilisin which was monitored at 390 n...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD100HPubMed
LigandPNGBDBM50056217(CHEMBL3353369)copy SMILES
Affinity DataKi:  12nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50389116(CHEMBL2064561)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ673WPubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50389117(CHEMBL2064562)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ673WPubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50389113(CHEMBL2064558)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ673WPubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50389120(CHEMBL2064565)copy SMILEScopy InChI
Affinity DataKi:  31nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ673WPubMed
LigandPNGBDBM34013(3-methylphenylalanine derivative, 22a)copy SMILEScopy InChI
Affinity DataKi:  32nM ΔG°:  -41.3kJ/molepH: 7.5 T: 2°CAssay Description:The cis/trans conversion of cis-Suc-AEPFpNA peptide by the PPIase led to the cleavage of para nitroaniline by subtilisin which was monitored at 390 n...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD100HPubMed
LigandPNGBDBM34014(3-methylphenylalanine derivative, 22b)copy SMILEScopy InChI
Affinity DataKi:  57nM ΔG°:  -40.0kJ/molepH: 7.5 T: 2°CAssay Description:The cis/trans conversion of cis-Suc-AEPFpNA peptide by the PPIase led to the cleavage of para nitroaniline by subtilisin which was monitored at 390 n...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50389109(CHEMBL2064557)copy SMILEScopy InChI
Affinity DataKi:  64nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50389119(CHEMBL2064564)copy SMILEScopy InChI
Affinity DataKi:  68nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ673WPubMed
LigandPNGBDBM50056216(CHEMBL3353368)copy SMILES
Affinity DataKi:  75nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
LigandPNGBDBM50056208(CHEMBL3322220)copy SMILES
Affinity DataKi:  76nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
LigandPNGBDBM34015(2,3-difluorophenylalanine derivative, 23a)copy SMILEScopy InChI
Affinity DataKi:  78nM ΔG°:  -39.2kJ/molepH: 7.5 T: 2°CAssay Description:The cis/trans conversion of cis-Suc-AEPFpNA peptide by the PPIase led to the cleavage of para nitroaniline by subtilisin which was monitored at 390 n...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD100HPubMed
LigandPNGBDBM50056214(CHEMBL3322219)copy SMILES
Affinity DataKi:  80nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
LigandPNGBDBM34016(2,3-difluorophenylalanine derivative, 23b)copy SMILEScopy InChI
Affinity DataKi:  89nM ΔG°:  -38.9kJ/molepH: 7.5 T: 2°CAssay Description:The cis/trans conversion of cis-Suc-AEPFpNA peptide by the PPIase led to the cleavage of para nitroaniline by subtilisin which was monitored at 390 n...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD100HPubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50389118(CHEMBL2064563)copy SMILEScopy InChI
Affinity DataKi:  98nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ673WPubMed
LigandPNGBDBM34009(naphthalene carboxamide, 18a)copy SMILEScopy InChI
Affinity DataKi:  100nM ΔG°:  -38.6kJ/molepH: 7.5 T: 2°CAssay Description:The cis/trans conversion of cis-Suc-AEPFpNA peptide by the PPIase led to the cleavage of para nitroaniline by subtilisin which was monitored at 390 n...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD100HPubMed
LigandPNGBDBM50056211(CHEMBL3322225)copy SMILES
Affinity DataKi:  138nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
LigandPNGBDBM50056204(CHEMBL3322215)copy SMILES
Affinity DataKi:  173nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
LigandPNGBDBM34010(benzothiophene carboxamide, 18b)copy SMILEScopy InChI
Affinity DataKi:  179nM ΔG°:  -37.2kJ/molepH: 7.5 T: 2°CAssay Description:The cis/trans conversion of cis-Suc-AEPFpNA peptide by the PPIase led to the cleavage of para nitroaniline by subtilisin which was monitored at 390 n...More data for this Ligand-Target Pair
LigandPNGBDBM50056205(CHEMBL3322216)copy SMILES
Affinity DataKi:  189nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
LigandPNGBDBM50056219(CHEMBL3322230)copy SMILES
Affinity DataKi:  196nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50389115(CHEMBL2064560)copy SMILEScopy InChI
Affinity DataKi:  207nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ673WPubMed
LigandPNGBDBM50056220(CHEMBL3322295)copy SMILES
Affinity DataKi:  320nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
LigandPNGBDBM50056215(CHEMBL3353367)copy SMILES
Affinity DataKi:  400nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
LigandPNGBDBM50056207(CHEMBL3322218)copy SMILES
Affinity DataKi:  424nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50389114(CHEMBL2064559)copy SMILEScopy InChI
Affinity DataKi:  512nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ673WPubMed
LigandPNGBDBM34008(amide, 17c)copy SMILEScopy InChI
Affinity DataKi:  525nM ΔG°:  -34.6kJ/molepH: 7.5 T: 2°CAssay Description:The cis/trans conversion of cis-Suc-AEPFpNA peptide by the PPIase led to the cleavage of para nitroaniline by subtilisin which was monitored at 390 n...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD100HPubMed
LigandPNGBDBM50056203(CHEMBL3322296)copy SMILES
Affinity DataKi:  580nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
LigandPNGBDBM50056206(CHEMBL3322217)copy SMILES
Affinity DataKi:  780nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
LigandPNGBDBM34005(pipecolate deriv., 12b)copy SMILEScopy InChI
Affinity DataKi:  800nM ΔG°:  -33.6kJ/molepH: 7.5 T: 2°CAssay Description:The cis/trans conversion of cis-Suc-AEPFpNA peptide by the PPIase led to the cleavage of para nitroaniline by subtilisin which was monitored at 390 n...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD100HPubMed
LigandPNGBDBM50056210(CHEMBL3322222)copy SMILES
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50389117(CHEMBL2064562)copy SMILEScopy InChI
Affinity DataKi:  1.16E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ673WPubMed
LigandPNGBDBM50056218(CHEMBL3322229)copy SMILES
Affinity DataKi:  1.36E+3nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
LigandPNGBDBM34003(pipecolate deriv., 11)copy SMILEScopy InChI
Affinity DataKi:  1.70E+3nM ΔG°:  -31.8kJ/molepH: 7.5 T: 2°CAssay Description:The cis/trans conversion of cis-Suc-AEPFpNA peptide by the PPIase led to the cleavage of para nitroaniline by subtilisin which was monitored at 390 n...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD100HPubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50389113(CHEMBL2064558)copy SMILEScopy InChI
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ673WPubMed
LigandPNGBDBM50056212(CHEMBL3322224)copy SMILES
Affinity DataKi:  1.90E+3nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50389116(CHEMBL2064561)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ673WPubMed
LigandPNGBDBM34007(urea, 17b)copy SMILEScopy InChI
Affinity DataKi:  4.13E+3nM ΔG°:  -29.7kJ/molepH: 7.5 T: 2°CAssay Description:The cis/trans conversion of cis-Suc-AEPFpNA peptide by the PPIase led to the cleavage of para nitroaniline by subtilisin which was monitored at 390 n...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD100HPubMed
LigandPNGBDBM34006(sulfonamide, 17a)copy SMILEScopy InChI
Affinity DataKi:  8.77E+3nM ΔG°:  -27.9kJ/molepH: 7.5 T: 2°CAssay Description:The cis/trans conversion of cis-Suc-AEPFpNA peptide by the PPIase led to the cleavage of para nitroaniline by subtilisin which was monitored at 390 n...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD100HPubMed
LigandPNGBDBM34004(pipecolate deriv., 12a)copy SMILEScopy InChI
Affinity DataKi:  9.46E+3nM ΔG°:  -27.7kJ/molepH: 7.5 T: 2°CAssay Description:The cis/trans conversion of cis-Suc-AEPFpNA peptide by the PPIase led to the cleavage of para nitroaniline by subtilisin which was monitored at 390 n...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD100HPubMed
LigandPNGBDBM50056213(CHEMBL3322223)copy SMILEScopy InChI
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
LigandPNGBDBM50056209(CHEMBL3322221)copy SMILEScopy InChI
Affinity DataKi:  4.60E+4nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JX1PubMed
LigandPNGBDBM34001(pipecolate deriv., 9)copy SMILEScopy InChI
Affinity DataKi: >5.00E+4nM ΔG°: >-23.7kJ/molepH: 7.5 T: 2°CAssay Description:The cis/trans conversion of cis-Suc-AEPFpNA peptide by the PPIase led to the cleavage of para nitroaniline by subtilisin which was monitored at 390 n...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD100HPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

LigandPNGBDBM31777(thieno[2,3-d]pyrimidine deriv., 2)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:DHFRs were assayed spectrophotometrically in the reaction buffer solution containing dihydrofolate. The reaction was initiated with an amount of enzy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RPKPubMed
Displayed 1 to 50 (of 218 total ) | Next | Last >>
Jump to: