Compile Data Set for Download or QSAR
Found 30 with Last Name = 'poirier' and Initial = 'j'
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM12578(2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosp...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Allosteric inhibition of human recombinant FPPS using GPP and [3H]IPP as substrate incubated with enzyme for 10 mins prior to substrate addition by l...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM12576(Bisphosphonate 1 | CHEMBL923 | JMC515594 Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Allosteric inhibition of human recombinant FPPS using GPP and [3H]IPP as substrate incubated with enzyme for 10 mins prior to substrate addition by l...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50443052(CHEMBL3087936 | US11279719, Example C-13)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Allosteric inhibition of human recombinant FPPS using GPP and [3H]IPP as substrate incubated with enzyme for 10 mins prior to substrate addition by l...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9KJRPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50421094(CHEMBL2088339)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Allosteric inhibition of human recombinant FPPS using GPP and [3H]IPP as substrate incubated with enzyme for 10 mins prior to substrate addition by l...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50432306(CHEMBL2347862)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Allosteric inhibition of human recombinant FPPS using GPP and [3H]IPP as substrate incubated with enzyme for 10 mins prior to substrate addition by l...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50138725((1-phosphono-2-pyridin-3-yl-ethyl)-phosphonic acid...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Allosteric inhibition of human recombinant FPPS using GPP and [3H]IPP as substrate incubated with enzyme for 10 mins prior to substrate addition by l...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9KJRPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50432306(CHEMBL2347862)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of FPPS (unknown origin)More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50443052(CHEMBL3087936 | US11279719, Example C-13)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of FPPS (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9KJRPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50022663(CHEMBL3299047)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of FPPS (unknown origin)More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50022664(CHEMBL3299048)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of FPPS (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9KJRPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50022666(CHEMBL3299050)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of FPPS (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9KJRPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50022667(CHEMBL3299051)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of FPPS (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9KJRPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50022668(CHEMBL3299149)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of FPPS (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9KJRPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50421094(CHEMBL2088339)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of FPPS (unknown origin)More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM36510(1-(Carboxymethyl)-1H-benzo[g]indole-2-carboxylic a...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of FPPS (unknown origin)More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50373092(CHEMBL261311)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of FPPS (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9KJRPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50138725((1-phosphono-2-pyridin-3-yl-ethyl)-phosphonic acid...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of FPPS (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9KJRPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM12576(Bisphosphonate 1 | CHEMBL923 | JMC515594 Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of FPPS (unknown origin)More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM12578(2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosp...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of FPPS (unknown origin)More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50022665(CHEMBL3299049)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of FPPS (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9KJRPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM36510(1-(Carboxymethyl)-1H-benzo[g]indole-2-carboxylic a...)copy SMILEScopy InChI
Affinity DataIC50: 920nMAssay Description:Allosteric inhibition of human recombinant FPPS using GPP and [3H]IPP as substrate incubated with enzyme for 10 mins prior to substrate addition by l...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50022668(CHEMBL3299149)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Allosteric inhibition of human recombinant FPPS using GPP and [3H]IPP as substrate incubated with enzyme for 10 mins prior to substrate addition by l...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9KJRPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50022667(CHEMBL3299051)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:Allosteric inhibition of human recombinant FPPS using GPP and [3H]IPP as substrate incubated with enzyme for 10 mins prior to substrate addition by l...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9KJRPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50022663(CHEMBL3299047)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:Allosteric inhibition of human recombinant FPPS using GPP and [3H]IPP as substrate incubated with enzyme for 10 mins prior to substrate addition by l...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50022664(CHEMBL3299048)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Allosteric inhibition of human recombinant FPPS using GPP and [3H]IPP as substrate incubated with enzyme for 10 mins prior to substrate addition by l...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9KJRPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50022666(CHEMBL3299050)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Allosteric inhibition of human recombinant FPPS using GPP and [3H]IPP as substrate incubated with enzyme for 10 mins prior to substrate addition by l...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9KJRPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50022665(CHEMBL3299049)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+4nMAssay Description:Allosteric inhibition of human recombinant FPPS using GPP and [3H]IPP as substrate incubated with enzyme for 10 mins prior to substrate addition by l...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9KJRPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50373092(CHEMBL261311)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+5nMAssay Description:Allosteric inhibition of human recombinant FPPS using GPP and [3H]IPP as substrate incubated with enzyme for 10 mins prior to substrate addition by l...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9KJRPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50022663(CHEMBL3299047)copy SMILEScopy InChI
Affinity DataKd:  9.20E+3nMAssay Description:Binding affinity to human FPPS by isothermal titration colorimetry in absence of Mg2+ ionsMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50432306(CHEMBL2347862)copy SMILEScopy InChI
Affinity DataKd:  3.20E+3nMAssay Description:Binding affinity to human FPPS by isothermal titration colorimetry in absence of Mg2+ ionsMore data for this Ligand-Target Pair