Compile Data Set for Download or QSAR
Found 166 with Last Name = 'pommery' and Initial = 'j'
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universit£ Lille-Nord de France

Curated by ChEMBL
LigandPNGBDBM50000829(6-((3-fluoro-5-(4-methoxytetrahydro-2H-pyran-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of 5-lipoxygenase in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B16PubMed
LigandPNGBDBM50108781(2-{[1-(2-Amino-3-mercapto-propionyl)-piperidin-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of Farnesyltransferase catalyzed transfer of the FPP moiety to dansyl-GCVLSMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z95N2PubMed
LigandPNGBDBM50108780(2-{2-[4-(2-Amino-3-methylsulfanyl-propylamino)-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of Farnesyltransferase catalyzed transfer of the FPP moiety to dansyl-GCVLSMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z95N2PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156581(3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)pheno...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of COX1 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50110484(3-((3-fluoro-5-(1-methoxycyclohexyl)phenoxy)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
LigandPNGBDBM50048955((S)-2-[4-((R)-2-Amino-3-mercapto-propionylamino)-b...)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of Farnesyltransferase catalyzed transfer of the FPP moiety to dansyl-GCVLSMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z95N2PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universit£ Lille-Nord de France

Curated by ChEMBL
LigandPNGBDBM50000829(6-((3-fluoro-5-(4-methoxytetrahydro-2H-pyran-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156577(1-(4-aminosulfonylphenyl)-3-[3-fluoro-5-(4-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of COX1 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B16PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universit£ Lille-Nord de France

Curated by ChEMBL
LigandPNGBDBM50110484(3-((3-fluoro-5-(1-methoxycyclohexyl)phenoxy)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of 5-lipoxygenase in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B16PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156584(1-(4-methanesulfonylphenyl)-3-[(3,4,5-trimethoxy)p...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156581(3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)pheno...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universit£ Lille-Nord de France

Curated by ChEMBL
LigandPNGBDBM50110484(3-((3-fluoro-5-(1-methoxycyclohexyl)phenoxy)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156594(3-[(3-fluoro-5-methoxy)phenoxymethyl]-1-(4-methane...)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50022271(2-(3-Benzoylphenyl)propionic acid | 2-(3-benzoylph...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibition of COX1 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DH6PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156580(3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)pheno...)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156590(1-(4-methanesulfonylphenyl)-3-[(3,4-methylenedioxy...)copy SMILEScopy InChI
Affinity DataIC50: 450nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50272731(2-(3-Benzoyl-phenyl)-propionic acid 2-nitrooxy-eth...)copy SMILEScopy InChI
Affinity DataIC50: 450nMAssay Description:Inhibition of COX1 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DH6PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50272677(2-[4-(Thiophene-2-carbonyl)-phenyl]-propionic acid...)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Inhibition of COX1 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DH6PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universit£ Lille-Nord de France

Curated by ChEMBL
LigandPNGBDBM50156585(3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)pheno...)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of COX2 in human whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of 12-hydroxyheptadecatrienoic acid production by HPLC methodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50090676((+-)-2-(p-(2-thenoyl)phenyl)propionic acid | 2-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 560nMAssay Description:Inhibition of COX1 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DH6PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50272676(2-[4-(Thiophene-2-carbonyl)-phenyl]-propionic acid...)copy SMILEScopy InChI
Affinity DataIC50: 570nMAssay Description:Inhibition of COX1 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DH6PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universit£ Lille-Nord de France

Curated by ChEMBL
LigandPNGBDBM50156582(3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)pheno...)copy SMILEScopy InChI
Affinity DataIC50: 570nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156587(3-[(5-cyano-3-fluoro)phenoxymethyl]-1-(4-methanesu...)copy SMILEScopy InChI
Affinity DataIC50: 570nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50272733(2-(3-Benzoyl-phenyl)-propionic acid 2,3-bis-nitroo...)copy SMILEScopy InChI
Affinity DataIC50: 580nMAssay Description:Inhibition of COX1 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DH6PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50272675(2-[4-(Thiophene-2-carbonyl)-phenyl]-propionic acid...)copy SMILEScopy InChI
Affinity DataIC50: 580nMAssay Description:Inhibition of COX1 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DH6PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50272732(2-(3-Benzoyl-phenyl)-propionic acid 2-nitrooxy-pro...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of COX1 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DH6PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156582(3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)pheno...)copy SMILEScopy InChI
Affinity DataIC50: 610nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50022271(2-(3-Benzoylphenyl)propionic acid | 2-(3-benzoylph...)copy SMILEScopy InChI
Affinity DataIC50: 690nMAssay Description:Inhibition of COX2 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DH6PubMedDrugBank
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universit£ Lille-Nord de France

Curated by ChEMBL
LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of 5-lipoxygenase in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B16PubMedDrugBank
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156583(1-(4-methanesulfonylphenyl)-3-[(3,4-dimethoxy)phen...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universit£ Lille-Nord de France

Curated by ChEMBL
LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood assessed as inhibition of LTB4 production by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B16PubMedDrugBank
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156579(1-(3,4-dichlorophenyl)-3-[3-fluoro-5-(4-methoxytet...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universit£ Lille-Nord de France

Curated by ChEMBL
LigandPNGBDBM50156586(3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)pheno...)copy SMILEScopy InChI
Affinity DataIC50: 720nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50272732(2-(3-Benzoyl-phenyl)-propionic acid 2-nitrooxy-pro...)copy SMILEScopy InChI
Affinity DataIC50: 730nMAssay Description:Inhibition of COX2 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DH6PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156591(1-(4-methanesulfonylphenyl)-3-[(3-nitro)phenoxymet...)copy SMILEScopy InChI
Affinity DataIC50: 740nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universit£ Lille-Nord de France

Curated by ChEMBL
LigandPNGBDBM50156577(1-(4-aminosulfonylphenyl)-3-[3-fluoro-5-(4-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 740nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50272733(2-(3-Benzoyl-phenyl)-propionic acid 2,3-bis-nitroo...)copy SMILEScopy InChI
Affinity DataIC50: 740nMAssay Description:Inhibition of COX2 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DH6PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universit£ Lille-Nord de France

Curated by ChEMBL
LigandPNGBDBM50156580(3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)pheno...)copy SMILEScopy InChI
Affinity DataIC50: 760nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universit£ Lille-Nord de France

Curated by ChEMBL
LigandPNGBDBM50156581(3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)pheno...)copy SMILEScopy InChI
Affinity DataIC50: 770nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50272731(2-(3-Benzoyl-phenyl)-propionic acid 2-nitrooxy-eth...)copy SMILEScopy InChI
Affinity DataIC50: 770nMAssay Description:Inhibition of COX2 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DH6PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of 12-hydroxyheptadecatrienoic acid production by HPLC methodMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universit£ Lille-Nord de France

Curated by ChEMBL
LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood assessed as inhibition of 5-hydroxyeicosatetraenoic acid production by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B16PubMedDrugBank
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universit£ Lille-Nord de France

Curated by ChEMBL
LigandPNGBDBM50156579(1-(3,4-dichlorophenyl)-3-[3-fluoro-5-(4-methoxytet...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156588(1-(4-trifluoromethoxyphenyl)-3-[3-fluoro-5-(4-meth...)copy SMILEScopy InChI
Affinity DataIC50: 820nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universit£ Lille-Nord de France

Curated by ChEMBL
LigandPNGBDBM50156589(1-(4-chlorophenyl)-3-[3-fluoro-5-(4-methoxytetrahy...)copy SMILEScopy InChI
Affinity DataIC50: 830nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universit£ Lille-Nord de France

Curated by ChEMBL
LigandPNGBDBM50156588(1-(4-trifluoromethoxyphenyl)-3-[3-fluoro-5-(4-meth...)copy SMILEScopy InChI
Affinity DataIC50: 850nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
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