Compile Data Set for Download or QSAR
Found 158 with Last Name = 'rahuel' and Initial = 'j'
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
Novartis Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50064333(CHEMBL49860 | Phosphoric acid mono-(2-amino-4-{2-a...)copy SMILEScopy InChI
Affinity DataIC50: 0.00400nMAssay Description:Inhibition of binding to Growth factor receptor bound protein 2 (Grb2) SH2 domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32TWKPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM17945((2S,4S,5S)-5-amino-N-butyl-4-hydroxy-9-[(2S)-2-[(m...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMpH: 7.2 T: 2°CAssay Description:In vitro potencies of compounds against purified human recombinant renin were determined by its cleavage of substrate angiotensinogen. The angiotensi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SGJPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18313((2R,4S,5S,7S)-5-amino-N-(2-acetamidoethyl)-4-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MSFPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18288((2R,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MSFPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM17949((2R,4S,5S,7S)-5-amino-N-butyl-4-hydroxy-7-{[4-meth...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 7.2 T: 2°CAssay Description:In vitro potencies of compounds against purified human recombinant renin were determined by its cleavage of substrate angiotensinogen. The angiotensi...More data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18337((2S,4S,5S,7S)-5-amino-N-[2,2-dimethyl-2-(methylcar...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W1PPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18342((2S,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W1PPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM17944(Renin nonpeptide inhibitor, 4 | methyl N-[(3R)-1-[...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMpH: 7.2 T: 2°CAssay Description:In vitro potencies of compounds against purified human recombinant renin were determined by its cleavage of substrate angiotensinogen. The angiotensi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SGJPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18278((2R,4S,5S,7S)-5-amino-7-{[3-(benzyloxy)-4-methoxyp...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MSFPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18340((2S,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W1PPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM17950((2S,4S,5S,7S)-5-amino-N-(2-carbamoyl-2,2-dimethyle...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMpH: 7.2 T: 2°CAssay Description:In vitro potencies of compounds against purified human recombinant renin were determined by its cleavage of substrate angiotensinogen. The angiotensi...More data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18344((2S,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W1PPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM17950((2S,4S,5S,7S)-5-amino-N-(2-carbamoyl-2,2-dimethyle...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18323((2S,4S,5S,7S)-5-amino-N-(3-carbamoylpropyl)-4-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W1PPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM17943(Renin nonpeptide inhibitor, 3 | methyl (3S)-1-[(5S...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMpH: 7.2 T: 2°CAssay Description:In vitro potencies of compounds against purified human recombinant renin were determined by its cleavage of substrate angiotensinogen. The angiotensi...More data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18338((2S,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W1PPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18326((2S,4S,5S,7S)-5-amino-N-[(1S)-1-carbamoylpropyl]-4...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W1PPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18289((2R,4S,5S,7S)-5-amino-4-hydroxy-N-(4-hydroxybutyl)...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MSFPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18334((2S,4S,5S,7S)-5-amino-N-[(2R)-2-carbamoyl-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W1PPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18336((2S,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W1PPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM17948((2R,4S,5S,7S)-5-amino-N-butyl-4-hydroxy-7-({[2-(3-...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMpH: 7.2 T: 2°CAssay Description:In vitro potencies of compounds against purified human recombinant renin were determined by its cleavage of substrate angiotensinogen. The angiotensi...More data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
Novartis Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50064333(CHEMBL49860 | Phosphoric acid mono-(2-amino-4-{2-a...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of binding to Grb2 SH2 domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32TWKPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18308((2R,4S,5S,7S)-5-amino-N-(3-carbamoylpropyl)-4-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MSFPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18306((2R,4S,5S,7S)-5-amino-N-(3-cyanopropyl)-4-hydroxy-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MSFPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18304(8-phenyl-octanecarboxamide peptidomimetic, 61 | me...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MSFPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM17949((2R,4S,5S,7S)-5-amino-N-butyl-4-hydroxy-7-{[4-meth...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM17941((2S,4S,5S)-5-[(2S)-2-[(2S)-2-benzyl-3-[(2-methylpr...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.2 T: 2°CAssay Description:In vitro potencies of compounds against purified human recombinant renin were determined by its cleavage of substrate angiotensinogen. The angiotensi...More data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18350((2S,4S,5S,7S)-5-amino-N-(2-carbamoyl-2,2-dimethyle...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W1PPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18339((2S,4S,5S,7S)-5-amino-N-[3-(dimethylcarbamoyl)prop...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W1PPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18335((2S,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W1PPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18333((2S,4S,5S,7S)-5-amino-N-[(2S)-2-carbamoyl-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W1PPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18331((2S,4S,5S,7S)-5-amino-N-[(2S)-1-carbamoylpropan-2-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W1PPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18322((2S,4S,5S,7S)-5-amino-N-(2-carbamoylethyl)-4-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W1PPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18321((2S,4S,5S,7S)-5-amino-N-butyl-4-hydroxy-7-{[4-meth...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W1PPubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
Novartis Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50078348(CHEMBL77689 | [(S)-1-[1-((S)-1,2-Dicarbamoyl-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Grb2-SH2 domain binding to phospho-EGF receptor intracellular C-terminal domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S181PHPubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
Novartis Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50078347(CHEMBL307890 | [(S)-1-[1-((1R,6S)-6-Carbamoyl-cycl...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of Grb2-SH2 domain binding to phospho-EGF receptor intracellular C-terminal domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S181PHPubMedMMDB
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18297((2R,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MSFPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18287((2R,4S,5S,7S)-5-amino-4-hydroxy-N-(3-hydroxypropyl...)copy SMILEScopy InChI
Affinity DataIC50: 2nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MSFPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18327((2S,4S,5S,7S)-5-amino-N-[(1S)-1-carbamoyl-2-hydrox...)copy SMILEScopy InChI
Affinity DataIC50: 2nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W1PPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18284((2R,4S,5S,7S)-5-amino-N-butyl-4-hydroxy-7-{[4-meth...)copy SMILEScopy InChI
Affinity DataIC50: 2nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MSFPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18341((2S,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W1PPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18298((2R,4S,5S,7S)-5-amino-N-[2-(1,1-dioxo-1,4-thiomorp...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MSFPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18316((2R,4S,5S,7S)-5-amino-N-[2-(dimethylsulfamoyl)ethy...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MSFPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18295((2R,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MSFPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18348((2S,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W1PPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18349((2S,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(4...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W1PPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18311((2R,4S,5S,7S)-5-amino-N-(4-carbamoylbutyl)-4-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MSFPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18312((2R,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MSFPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18310((2R,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MSFPubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM18320((2R,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7MSFPubMed
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