Compile Data Set for Download or QSAR
Found 978 with Last Name = 'roderick' and Initial = 'j'
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
The DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50064340((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-[(R)-2-(4-met...)copy SMILEScopy InChI
Affinity DataKi:  0.130nMAssay Description:Inhibition of MMP-9 (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB235NPubMed
TargetCollagenase 3(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50102594(7-Isobutyl-8-oxo-2-oxa-9-aza-bicyclo[10.2.2]hexade...)copy SMILEScopy InChI
Affinity DataKi:  0.450nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50102594(7-Isobutyl-8-oxo-2-oxa-9-aza-bicyclo[10.2.2]hexade...)copy SMILEScopy InChI
Affinity DataKi:  0.5nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104981(11-(2',6'-Difluoro-biphenyl-4-ylmethyl)-2,10-dioxo...)copy SMILEScopy InChI
Affinity DataKi:  0.640nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD6XRTPubMed
TargetMatrilysin(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50102594(7-Isobutyl-8-oxo-2-oxa-9-aza-bicyclo[10.2.2]hexade...)copy SMILEScopy InChI
Affinity DataKi:  0.800nMAssay Description:Inhibition of matrix metalloprotease-7More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
The DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50064340((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-[(R)-2-(4-met...)copy SMILEScopy InChI
Affinity DataKi:  0.870nMAssay Description:Inhibition of MMP-1 (Matrix metalloproteinase-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB235NPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
The DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50102594(7-Isobutyl-8-oxo-2-oxa-9-aza-bicyclo[10.2.2]hexade...)copy SMILEScopy InChI
Affinity DataKi:  0.900nMAssay Description:In vitro inhibition of human MMP-9.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
The DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50076995((6S,9R,10S)-10-Hydroxycarbamoyl-9-isobutyl-6-methy...)copy SMILEScopy InChI
Affinity DataKi: <1nMAssay Description:In vitro inhibition of human MMP-9.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
The DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50076991((2S,11S,12R)-7-Benzenesulfonyl-12-isobutyl-13-oxo-...)copy SMILEScopy InChI
Affinity DataKi: <1nMAssay Description:In vitro inhibition of human MMP-9.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
The DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50076991((2S,11S,12R)-7-Benzenesulfonyl-12-isobutyl-13-oxo-...)copy SMILEScopy InChI
Affinity DataKi: <1nMAssay Description:In vitro inhibition of human MMP-1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
The DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)copy SMILEScopy InChI
Affinity DataKi: <1nMAssay Description:In vitro inhibition of human MMP-1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMedDrugBank
TargetInterstitial collagenase(Homo sapiens (Human))
The DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50102604(11-Isobutyl-2,10-dioxo-1-oxa-3,9-diaza-cyclopentad...)copy SMILEScopy InChI
Affinity DataKi: <1nMAssay Description:In vitro inhibition of human MMP-1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
The DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50102630(11-Isobutyl-3-methyl-2,10-dioxo-1-oxa-3,9-diaza-cy...)copy SMILEScopy InChI
Affinity DataKi: <1nMAssay Description:In vitro inhibition of human MMP-9.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
The DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50102630(11-Isobutyl-3-methyl-2,10-dioxo-1-oxa-3,9-diaza-cy...)copy SMILEScopy InChI
Affinity DataKi: <1nMAssay Description:In vitro inhibition of human MMP-1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
The DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50076993((2S,11S,12R)-12-Isobutyl-13-oxo-1,7diaza-cyclotrid...)copy SMILEScopy InChI
Affinity DataKi: <1nMAssay Description:In vitro inhibition of human MMP-1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
The DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50102631(8-Isobutyl-9-oxo-6-oxa-1,10-diaza-tricyclo[11.6.1....)copy SMILEScopy InChI
Affinity DataKi: <1nMAssay Description:In vitro inhibition of human MMP-1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
The DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)copy SMILEScopy InChI
Affinity DataKi: <1nMAssay Description:In vitro inhibition of human MMP-9.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMedDrugBank
TargetInterstitial collagenase(Homo sapiens (Human))
The DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50064340((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-[(R)-2-(4-met...)copy SMILEScopy InChI
Affinity DataKi: <1nMAssay Description:In vitro inhibition of human MMP-1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
The DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50064340((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-[(R)-2-(4-met...)copy SMILEScopy InChI
Affinity DataKi: <1nMAssay Description:In vitro inhibition of human MMP-9.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
The DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50102600(12-Isobutyl-4-methyl-3,11-dioxo-1-oxa-4,10-diaza-c...)copy SMILEScopy InChI
Affinity DataKi: <1nMAssay Description:In vitro inhibition of human MMP-1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
The DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50102610(10-Isobutyl-6,11-dioxo-6,7,9,10,11,12,13,14-octahy...)copy SMILEScopy InChI
Affinity DataKi: <1nMAssay Description:In vitro inhibition of human MMP-1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
The DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50076995((6S,9R,10S)-10-Hydroxycarbamoyl-9-isobutyl-6-methy...)copy SMILEScopy InChI
Affinity DataKi: <1nMAssay Description:In vitro inhibition of human MMP-1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50102594(7-Isobutyl-8-oxo-2-oxa-9-aza-bicyclo[10.2.2]hexade...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50102608(11-Isobutyl-2,10-dioxo-1-oxa-3,9-diaza-cyclopentad...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD6XRTPubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50102608(11-Isobutyl-2,10-dioxo-1-oxa-3,9-diaza-cyclopentad...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
The DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50102604(11-Isobutyl-2,10-dioxo-1-oxa-3,9-diaza-cyclopentad...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:In vitro inhibition of human MMP-9.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50102608(11-Isobutyl-2,10-dioxo-1-oxa-3,9-diaza-cyclopentad...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
The DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50064341((6S,7R,10S)-7-Isobutyl-8-oxo-2-oxa-9-aza-bicyclo[1...)copy SMILEScopy InChI
Affinity DataKi:  1.20nMAssay Description:In vitro inhibition of human MMP-1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
The DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50102608(11-Isobutyl-2,10-dioxo-1-oxa-3,9-diaza-cyclopentad...)copy SMILEScopy InChI
Affinity DataKi:  1.20nMAssay Description:In vitro inhibition of human MMP-9.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
The DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50102608(11-Isobutyl-2,10-dioxo-1-oxa-3,9-diaza-cyclopentad...)copy SMILEScopy InChI
Affinity DataKi:  1.20nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD6XRTPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
The DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50064341((6S,7R,10S)-7-Isobutyl-8-oxo-2-oxa-9-aza-bicyclo[1...)copy SMILEScopy InChI
Affinity DataKi:  1.20nMAssay Description:Inhibition of MMP-1 (Matrix metalloproteinase-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB235NPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
The DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50102640(12-Isobutyl-8,13-dioxo-1,7diaza-cyclotridecane-2,1...)copy SMILEScopy InChI
Affinity DataKi:  1.40nMAssay Description:In vitro inhibition of human MMP-1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104974(2,10-Dioxo-11-(2'-trifluoromethyl-biphenyl-4-ylmet...)copy SMILEScopy InChI
Affinity DataKi:  1.5nMAssay Description:Inhibition of porcine TNF-alpha converting enzyme(pTACE).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD6XRTPubMed
TargetMatrilysin(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50102608(11-Isobutyl-2,10-dioxo-1-oxa-3,9-diaza-cyclopentad...)copy SMILEScopy InChI
Affinity DataKi:  1.5nMAssay Description:Inhibition of matrix metalloprotease-7More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104973(2,10-Dioxo-11-(2'-trifluoromethyl-biphenyl-4-ylmet...)copy SMILEScopy InChI
Affinity DataKi:  1.70nMAssay Description:Inhibition of porcine TNF-alpha converting enzyme(pTACE).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD6XRTPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
The DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50064341((6S,7R,10S)-7-Isobutyl-8-oxo-2-oxa-9-aza-bicyclo[1...)copy SMILEScopy InChI
Affinity DataKi:  1.80nMAssay Description:Inhibition of MMP-9 (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB235NPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
The DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50102658(7-Isobutyl-8-oxo-2-oxa-9-aza-bicyclo[12.2.2]octade...)copy SMILEScopy InChI
Affinity DataKi:  1.80nMAssay Description:In vitro inhibition of human MMP-1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
The DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50064341((6S,7R,10S)-7-Isobutyl-8-oxo-2-oxa-9-aza-bicyclo[1...)copy SMILEScopy InChI
Affinity DataKi:  1.80nMAssay Description:In vitro inhibition of human MMP-9.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
TargetStromelysin-1(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50064340((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-[(R)-2-(4-met...)copy SMILEScopy InChI
Affinity DataKi:  1.90nMAssay Description:Inhibition of human MMP-3.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
TargetStromelysin-1(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50064340((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-[(R)-2-(4-met...)copy SMILEScopy InChI
Affinity DataKi:  1.93nMAssay Description:Inhibition of MMP-3 (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB235NPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
The DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50102614(7-Isobutyl-8-oxo-2-oxa-9-aza-bicyclo[11.2.2]heptad...)copy SMILEScopy InChI
Affinity DataKi:  2.10nMAssay Description:In vitro inhibition of human MMP-9.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
TargetCollagenase 3(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50102608(11-Isobutyl-2,10-dioxo-1-oxa-3,9-diaza-cyclopentad...)copy SMILEScopy InChI
Affinity DataKi:  2.30nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
TargetStromelysin-1(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)copy SMILEScopy InChI
Affinity DataKi:  2.40nMAssay Description:Inhibition of human MMP-3.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMedDrugBank
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
The DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50064339((9S,12R,13S)-12-Isobutyl-3,11-dioxo-1-oxa-4,10-dia...)copy SMILEScopy InChI
Affinity DataKi:  2.60nMAssay Description:Inhibition of MMP-9 (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB235NPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
The DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50064339((9S,12R,13S)-12-Isobutyl-3,11-dioxo-1-oxa-4,10-dia...)copy SMILEScopy InChI
Affinity DataKi:  2.60nMAssay Description:In vitro inhibition of human MMP-9.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104975((8S,11R,12S)-2,10-Dioxo-11-(2'-trifluoromethyl-bip...)copy SMILEScopy InChI
Affinity DataKi:  2.80nMAssay Description:Inhibition of porcine TNF-alpha converting enzyme(pTACE).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD6XRTPubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104975((8S,11R,12S)-2,10-Dioxo-11-(2'-trifluoromethyl-bip...)copy SMILEScopy InChI
Affinity DataKi:  2.80nMAssay Description:Inhibition of porcine TACEMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72GV7PubMed
TargetInterstitial collagenase(Homo sapiens (Human))
The DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50064339((9S,12R,13S)-12-Isobutyl-3,11-dioxo-1-oxa-4,10-dia...)copy SMILEScopy InChI
Affinity DataKi:  2.80nMAssay Description:In vitro inhibition of human MMP-1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104977(11-(3',5'-Dichloro-biphenyl-4-ylmethyl)-2,10-dioxo...)copy SMILEScopy InChI
Affinity DataKi:  2.80nMAssay Description:Inhibition of porcine TNF-alpha converting enzyme(pTACE).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD6XRTPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
The DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50064339((9S,12R,13S)-12-Isobutyl-3,11-dioxo-1-oxa-4,10-dia...)copy SMILEScopy InChI
Affinity DataKi:  2.80nMAssay Description:Inhibition of MMP-1 (Matrix metalloproteinase-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB235NPubMed
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