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Found 442 with Last Name = 'sipthorp' and Initial = 'j'
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554469(CHEMBL4796694)copy SMILES
Affinity DataIC50: 0.0510nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554470(CHEMBL4752559)copy SMILES
Affinity DataIC50: 0.0750nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554462(CHEMBL4784029)copy SMILES
Affinity DataIC50: 0.190nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554475(CHEMBL4757064)copy SMILES
Affinity DataIC50: 0.190nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554471(CHEMBL4761454)copy SMILES
Affinity DataIC50: 0.260nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554479(CHEMBL4741570)copy SMILES
Affinity DataIC50: 0.260nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554472(CHEMBL4787488)copy SMILES
Affinity DataIC50: 0.270nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554464(CHEMBL4750152)copy SMILES
Affinity DataIC50: 0.350nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554484(CHEMBL4747825)copy SMILES
Affinity DataIC50: 0.430nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554480(CHEMBL4757561)copy SMILES
Affinity DataIC50: 0.450nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554467(CHEMBL4759088)copy SMILES
Affinity DataIC50: 0.460nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554477(CHEMBL2426243)copy SMILES
Affinity DataIC50: 0.780nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539233(CHEMBL4642625)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539213(CHEMBL4637176)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50154397(CHEMBL3774760)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50154397(CHEMBL3774760)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554476(CHEMBL4782633)copy SMILES
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554465(CHEMBL4776064)copy SMILES
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539244(CHEMBL4648963)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539211(CHEMBL4642915)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539246(CHEMBL4632439)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554483(CHEMBL4085008)copy SMILES
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554457(CHEMBL4793575)copy SMILES
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554473(CHEMBL4754273)copy SMILES
Affinity DataIC50: 2nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539220(CHEMBL4646043)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539221(CHEMBL4637948)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539212(CHEMBL4648770)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554456(CHEMBL4791705)copy SMILES
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM601043(4-[2,4-dichloro-3-(trifluoromethyl)phenyl]-1H-tria...)copy SMILES
Affinity DataIC50: 2.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS31FM
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554481(CHEMBL4743027)copy SMILES
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM601048(2-[2,4-dichloro-3-(trifluoromethyl)phenyl]-1,3,4-o...)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS31FM
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50154387(CHEMBL3774528)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554468(CHEMBL4749659)copy SMILES
Affinity DataIC50: 3nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554478(CHEMBL4763193)copy SMILES
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539243(CHEMBL4637227)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539214(CHEMBL4641132)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50554474(CHEMBL4761164)copy SMILES
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM600981(2-(2,4-dichloro-3-(trifluoromethyl)phenyl)-5-(meth...)copy SMILES
Affinity DataIC50: 3.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS31FM
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50427205(CHEMBL2324854)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539222(CHEMBL4643862)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539223(CHEMBL4634865)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539248(CHEMBL4633059)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human Notum (S81-T451 residues) C330S mutant expressed in HEK293S cells using OPTS substrate incubated for 40 mins by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2988BNVPubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539248(CHEMBL4633059)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539234(CHEMBL4641550)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50539216(CHEMBL4636343)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM600982(2-(2,4-dichloro-3-(trifluoromethyl)phenyl)-5-ethox...)copy SMILES
Affinity DataIC50: 4.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS31FM
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM601045(4,5-dideuterio-1-[2,4-dichloro-3-(trifluoromethyl)...)copy SMILES
Affinity DataIC50: 4.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS31FM
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM601033(1-[2,4-dichloro-3-(trifluoromethyl)phenyl]triazole...)copy SMILES
Affinity DataIC50: 4.60nMMore data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM601001(5-[2,4-dichloro-3-(trifluoromethyl)phenyl]-1,3,4-o...)copy SMILES
Affinity DataIC50: 5.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS31FM
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))TBA
LigandPNGBDBM50154370(CHEMBL1689356)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:Inhibition of human His6-tagged NOTUM (81 to 451 residues) Cys330Ser mutant transfected in HEK293S cells using OPTS as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8B58PubMed
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