Compile Data Set for Download or QSAR
Found 187 with Last Name = 'stasch' and Initial = 'j'
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM312960(3-[1-(2,3-Difluoro-4-methylbenzyl)-5-fluoro-6-meth...)copy SMILEScopy InChI
Affinity DataIC50: 0.25nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ0BC2US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM312961(3-[1-(2,3-Difluoro-4-methylbenzyl)-6-methyl-1H-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 0.650nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ0BC2US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM312944(3-[5-Fluoro-1-(2-fluoro-4-methylbenzyl)-6-methyl-1...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ0BC2US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM312945(3-[1-(2-Fluoro-4-methylbenzyl)-6-methyl-1H-pyrazol...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ0BC2US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM312965(3′-[1-(2,3-Difluoro-4-methylbenzyl)-6-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ0BC2US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM312950(3-[1-(4-Chloro-2-fluorobenzyl)-6-methyl-1H-pyrazol...)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ0BC2US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM312933( 3-[1-(2,3-Difluorobenzyl)-5-fluoro-6-methyl-1H-py...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ0BC2US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM312942(Sodium 3-[1-(2,3-difluorobenzyl)-5-fluoro-6-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ0BC2US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM312948(3-[1-(4-Chloro-2-fluorobenzyl)-5-fluoro-6-methyl-1...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ0BC2US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM312958(3-[5-Fluoro-1-(3-fluoro-4-methylbenzyl)-6-methyl-1...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ0BC2US Patent
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Bayer HealthCare AG

LigandPNGBDBM50171626(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition assay using ECE.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ604CPubMed
TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Bayer HealthCare AG

LigandPNGBDBM97371(ECE Inhibitor, 14)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition assay using ECE.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ604CPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM312959(3-[1-(3-Fluoro-4-methylbenzyl)-6-methyl-1H-pyrazol...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ0BC2US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM258372(US9505786, 10)copy SMILEScopy InChI
Affinity DataIC50: 15nMpH: 7.5 T: 2°CAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8S6VUS Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM258417(US9505786, 61)copy SMILEScopy InChI
Affinity DataIC50: 15nMpH: 7.5 T: 2°CAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8S6VUS Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM312962(3′-[1-(2-Fluoro-4-methylbenzyl)-6-methyl-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ0BC2US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM157148(US9023849, 18)copy SMILEScopy InChI
Affinity DataIC50: 16nMpH: 7.5Assay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TD9W3QUS Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM312952(7,7-Dimethyl-3-[6-methyl-1-(2,3,6-trifluorobenzyl)...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ0BC2US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM312963(3′-[1-(2,3-Difluorobenzyl)-6-methyl-1H-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ0BC2US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM312946(3-[1-(2,4-Difluorobenzyl)-5-fluoro-6-methyl-1H-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ0BC2US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM258383(US9505786, 21)copy SMILEScopy InChI
Affinity DataIC50: 22nMpH: 7.5 T: 2°CAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8S6VUS Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM312957(3-[1-(2,6-Difluorobenzyl)-6-methyl-1H-pyrazolo[3,4...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ0BC2US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM157153(US9023849, 24)copy SMILEScopy InChI
Affinity DataIC50: 25nMpH: 7.5Assay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TD9W3QUS Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM312951(3-[5-Fluoro-6-methyl-1-(2,3,6-trifluorobenzyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ0BC2US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM312947(3-[1-(2,4-Difluorobenzyl)-6-methyl-1H-pyrazolo[3,4...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ0BC2US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM258381(US9505786, 19)copy SMILEScopy InChI
Affinity DataIC50: 38nMpH: 7.5 T: 2°CAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8S6VUS Patent
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
BAYER HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50171626(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derivedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H994R9PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM258377(US9505786, 15)copy SMILEScopy InChI
Affinity DataIC50: 40nMpH: 7.5 T: 2°CAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8S6VUS Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM258411(US9505786, 53)copy SMILEScopy InChI
Affinity DataIC50: 41nMpH: 7.5 T: 2°CAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8S6VUS Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM312953(3-[1-(3-Chloro-2-fluorobenzyl)-5-fluoro-6-methyl-1...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ0BC2US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM258386(US9505786, 24)copy SMILEScopy InChI
Affinity DataIC50: 48nMpH: 7.5 T: 2°CAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8S6VUS Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM312955(3-[1-(3-Chloro-2-fluorobenzyl)-6-methyl-1H-pyrazol...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ0BC2US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM157146(US9023849, 16)copy SMILEScopy InChI
Affinity DataIC50: 64nMpH: 7.5Assay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TD9W3QUS Patent
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
BAYER HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50171614(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derivedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H994R9PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM312956(3-[1-(2,6-Difluorobenzyl)-5-fluoro-6-methyl-1H-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ0BC2US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM157150(US9023849, 21)copy SMILEScopy InChI
Affinity DataIC50: 75nMpH: 7.5Assay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TD9W3QUS Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM157141(US9023849, 9)copy SMILEScopy InChI
Affinity DataIC50: 85nMpH: 7.5Assay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TD9W3QUS Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM157155(US9023849, 26)copy SMILEScopy InChI
Affinity DataIC50: 95nMpH: 7.5Assay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TD9W3QUS Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM258394(US9505786, 32)copy SMILEScopy InChI
Affinity DataIC50: 110nMpH: 7.5 T: 2°CAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8S6VUS Patent
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
BAYER HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50171611(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derivedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H994R9PubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
BAYER HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50171633(1-(2-Fluoro-benzyl)-5-[2-(1-methyl-cyclopentyl)-ac...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H994R9PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM258407(US9505786, 46)copy SMILEScopy InChI
Affinity DataIC50: 120nMpH: 7.5 T: 2°CAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8S6VUS Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM258397(US9505786, 35)copy SMILEScopy InChI
Affinity DataIC50: 120nMpH: 7.5 T: 2°CAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8S6VUS Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM258392(US9505786, 30)copy SMILEScopy InChI
Affinity DataIC50: 130nMpH: 7.5 T: 2°CAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8S6VUS Patent
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
BAYER HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50171630(5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H994R9PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM258384(US9505786, 22)copy SMILEScopy InChI
Affinity DataIC50: 130nMpH: 7.5 T: 2°CAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8S6VUS Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM258409(US9505786, 51)copy SMILEScopy InChI
Affinity DataIC50: 140nMpH: 7.5 T: 2°CAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8S6VUS Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM258385(US9505786, 23)copy SMILEScopy InChI
Affinity DataIC50: 140nMpH: 7.5 T: 2°CAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8S6VUS Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM258412(US9505786, 54)copy SMILEScopy InChI
Affinity DataIC50: 145nMpH: 7.5 T: 2°CAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8S6VUS Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER PHARMA AKTIENGESELLSCHAFT

US Patent
LigandPNGBDBM258370(US9505786, 8)copy SMILEScopy InChI
Affinity DataIC50: 150nMpH: 7.5 T: 2°CAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8S6VUS Patent
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