Compile Data Set for Download or QSAR
Found 32 with Last Name = 'doiron' and Initial = 'ja'
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50583291(CHEMBL5085074)copy SMILES
Affinity DataIC50: 200nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W099TKPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50583293(CHEMBL5088008)copy SMILES
Affinity DataIC50: 200nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W099TKPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50583295(CHEMBL5093372)copy SMILES
Affinity DataIC50: 210nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W099TKPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50583289(CHEMBL5080803)copy SMILES
Affinity DataIC50: 230nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W099TKPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50583294(CHEMBL5072274)copy SMILES
Affinity DataIC50: 240nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W099TKPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50583290(CHEMBL5088166)copy SMILES
Affinity DataIC50: 240nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W099TKPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50583296(CHEMBL5085633)copy SMILES
Affinity DataIC50: 250nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W099TKPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50583308(CHEMBL5089203)copy SMILES
Affinity DataIC50: 270nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W099TKPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50583302(CHEMBL5071392)copy SMILES
Affinity DataIC50: 270nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W099TKPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50583307(CHEMBL5072348)copy SMILES
Affinity DataIC50: 300nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W099TKPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50583288(CHEMBL4794186)copy SMILES
Affinity DataIC50: 300nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W099TKPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50029225((E)-3-(2,5-Dihydroxy-phenyl)-acrylic acid phenethy...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibition of 5-LO in human PMNL cells assessed as reduction in leukotriene formation preincubated for 5 mins followed by thapsigargin stimulation me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125X31PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50029225((E)-3-(2,5-Dihydroxy-phenyl)-acrylic acid phenethy...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibition of 5-LO in human PMNL cells assessed as reduction in leukotriene formation preincubated for 5 mins followed by thapsigargin stimulation me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125X31PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50583298(CHEMBL4759754)copy SMILES
Affinity DataIC50: 340nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W099TKPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50583292(CHEMBL5073724)copy SMILES
Affinity DataIC50: 350nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W099TKPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50583303(CHEMBL5092055)copy SMILES
Affinity DataIC50: 410nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W099TKPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50583304(CHEMBL5077729)copy SMILES
Affinity DataIC50: 420nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W099TKPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50530377(CHEMBL4579523)copy SMILEScopy InChI
Affinity DataIC50: 530nMAssay Description:Inhibition of 5-LO in human PMNL cells assessed as reduction in leukotriene formation preincubated for 5 mins followed by thapsigargin stimulation me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125X31PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50530377(CHEMBL4579523)copy SMILEScopy InChI
Affinity DataIC50: 530nMAssay Description:Inhibition of 5-LO in human PMNL cells assessed as reduction in leukotriene formation preincubated for 5 mins followed by thapsigargin stimulation me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125X31PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50583306(CHEMBL5084797)copy SMILES
Affinity DataIC50: 560nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W099TKPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50583301(CHEMBL5078319)copy SMILES
Affinity DataIC50: 590nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W099TKPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50583297(CHEMBL5084822)copy SMILES
Affinity DataIC50: 710nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W099TKPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50530376(CHEMBL4582170)copy SMILEScopy InChI
Affinity DataIC50: 890nMAssay Description:Inhibition of 5-LO in human PMNL cells assessed as reduction in leukotriene formation preincubated for 5 mins followed by thapsigargin stimulation me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125X31PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50530376(CHEMBL4582170)copy SMILEScopy InChI
Affinity DataIC50: 890nMAssay Description:Inhibition of 5-LO in human PMNL cells assessed as reduction in leukotriene formation preincubated for 5 mins followed by thapsigargin stimulation me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125X31PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50583299(CHEMBL5084841)copy SMILES
Affinity DataIC50: 960nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W099TKPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50029207((E)-3-(3,4-Dihydroxy-phenyl)-acrylic acid phenethy...)copy SMILEScopy InChI
Affinity DataIC50: 970nMAssay Description:Inhibition of 5-LO in human PMNL cells assessed as reduction in leukotriene formation preincubated for 5 mins followed by thapsigargin stimulation me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125X31PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50029207((E)-3-(3,4-Dihydroxy-phenyl)-acrylic acid phenethy...)copy SMILEScopy InChI
Affinity DataIC50: 970nMAssay Description:Inhibition of 5-LO in human PMNL cells assessed as reduction in leukotriene formation preincubated for 5 mins followed by thapsigargin stimulation me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125X31PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50583305(CHEMBL5079669)copy SMILES
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W099TKPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50583300(CHEMBL5074759)copy SMILES
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W099TKPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)copy SMILEScopy InChI
Affinity DataIC50: 2.31E+3nMAssay Description:Inhibition of 5-LO in human PMNL cells assessed as reduction in leukotriene formation preincubated for 5 mins followed by thapsigargin stimulation me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125X31PubMedDrugBank
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)copy SMILEScopy InChI
Affinity DataIC50: 2.31E+3nMAssay Description:Inhibition of 5-LO in human PMNL cells assessed as reduction in leukotriene formation preincubated for 5 mins followed by thapsigargin stimulation me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125X31PubMedDrugBank
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)copy SMILEScopy InChI
Affinity DataIC50: 2.31E+3nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W099TKPubMedDrugBank