Compile Data Set for Download or QSAR
Found 200 with Last Name = 'siuciak' and Initial = 'ja'
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50206243(CHEMBL3918431)copy SMILEScopy InChI
Affinity DataKi:  4.40nMAssay Description:Displacement of [125I]Tyr54-alpha-bungarotoxin from rat alpha7 nAChR expressed in HEK293 cell membranes co-expressing human RIC3 measured after 2 hrs...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0X2HPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50343301(2-((4-(4-Fluorophenyl)piperidin-1-yl)methyl)-1-met...)copy SMILEScopy InChI
Affinity DataKi:  24nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222V3CPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50211195(CHEMBL3944506)copy SMILEScopy InChI
Affinity DataKi:  38nMAssay Description:Displacement of [125I]Tyr54-alpha-bungarotoxin from rat alpha7 nAChR expressed in HEK293 cell membranes co-expressing human RIC3 measured after 2 hrs...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0X2HPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50343305(2-((4-(4-Chloro-2-fluorophenyl)piperidin-1-yl)meth...)copy SMILEScopy InChI
Affinity DataKi:  91nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222V3CPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50164613((-)-Spiro[1-azabicyclo(2.2.2)octane-3,5'-oxazolidi...)copy SMILEScopy InChI
Affinity DataKi:  92nMAssay Description:Displacement of [125I]alpha-bungarotoxin from rat hippocampal alpha7 nAChR measured after 2 hrs by TopCount scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0X2HPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50343299(2-((4-(2-Fluorophenyl)piperidin-1-yl)methyl)-1-met...)copy SMILEScopy InChI
Affinity DataKi:  93nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222V3CPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50277957((R)-3-((2',4'-difluorobiphenyl-4-yl)methyl)-5-meth...)copy SMILEScopy InChI
Affinity DataKi:  323nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F18ZK7PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50343317(1-methyl-2-(((1R,5S)-3-(4-(trifluoromethyl)phenyl)...)copy SMILEScopy InChI
Affinity DataKi:  355nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222V3CPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50343308(1-Methyl-2-((4-(4-(trifluoromethyl)phenyl)piperidi...)copy SMILEScopy InChI
Affinity DataKi:  404nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222V3CPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50343295(2-((4-(2-Methoxy-phenyl)piperidin-1-yl)methyl)-1-m...)copy SMILEScopy InChI
Affinity DataKi:  426nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222V3CPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50343306(1-methyl-2-((4-(4-(trifluoromethyl)phenyl)piperidi...)copy SMILEScopy InChI
Affinity DataKi:  561nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222V3CPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50343316(CHEMBL1774224 | cis-1-methyl-2-(((2R,4R)-2-methyl-...)copy SMILEScopy InChI
Affinity DataKi:  589nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222V3CPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50343309(1-Methyl-2-((4-(4-(trifluoromethyl)phenyl)piperidi...)copy SMILEScopy InChI
Affinity DataKi:  671nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222V3CPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50343314(2-((4-(2-Fluoro-4-(trifluoromethoxy)phenyl)piperid...)copy SMILEScopy InChI
Affinity DataKi:  1.18E+3nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222V3CPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50343321(CHEMBL1774229 | cis-2-(((3R,4R)-4-(4-chloro-2-fluo...)copy SMILEScopy InChI
Affinity DataKi:  1.62E+3nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222V3CPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50343313(2-((4-(2-Fluoro-4-(trifluoromethyl)phenyl)piperidi...)copy SMILEScopy InChI
Affinity DataKi:  1.78E+3nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222V3CPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50277955((R)-3-((3'-chloro-4'-fluorobiphenyl-4-yl)methyl)-5...)copy SMILEScopy InChI
Affinity DataKi:  2.10E+3nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F18ZK7PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50343312(2-((4-(2-Methoxy-4-(trifluoromethyl)phenyl)piperid...)copy SMILEScopy InChI
Affinity DataKi:  2.43E+3nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222V3CPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50343318((S)-2-((3,3-dimethyl-4-(4-(trifluoromethyl)phenyl)...)copy SMILEScopy InChI
Affinity DataKi: >2.80E+3nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222V3CPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50343319(CHEMBL1774227 | cis-1-methyl-2-(((3R,4R)-3-methyl-...)copy SMILEScopy InChI
Affinity DataKi: >2.80E+3nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222V3CPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50343320(CHEMBL1774228 | cis-1-methyl-2-(((3S,4S)-3-methyl-...)copy SMILEScopy InChI
Affinity DataKi: >2.80E+3nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222V3CPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50343319(CHEMBL1774227 | cis-1-methyl-2-(((3R,4R)-3-methyl-...)copy SMILEScopy InChI
Affinity DataKi: >2.80E+3nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222V3CPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50278009((R)-3-((6-(3,4-difluorophenyl)pyridin-3-yl)methyl)...)copy SMILEScopy InChI
Affinity DataKi: >3.10E+3nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F18ZK7PubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50277956((R)-3-((2'-fluoro-4'-(trifluoromethoxy)biphenyl-4-...)copy SMILEScopy InChI
Affinity DataKi: >3.10E+3nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F18ZK7PubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50278007((R)-3-((6-(2-fluoro-4-(trifluoromethoxy)phenyl)pyr...)copy SMILEScopy InChI
Affinity DataKi: >3.10E+3nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F18ZK7PubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50277846((5R)-3-(4-(1-cyclohexylethoxy)benzyl)-5-methyloxaz...)copy SMILEScopy InChI
Affinity DataKi: >3.20E+3nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F18ZK7PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50343327(CHEMBL1774235 | cis-2-(((3R,4R)-4-(2-fluoro-4-(tri...)copy SMILEScopy InChI
Affinity DataKi: >4.68E+3nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222V3CPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50343325(CHEMBL1774233 | cis-2-(((3R,4R)-4-(2-fluoro-4-(tri...)copy SMILEScopy InChI
Affinity DataKi: >5.26E+3nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222V3CPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50343323(CHEMBL1774231 | cis-2-(((3R,4R)-4-(2-methoxy-4-(tr...)copy SMILEScopy InChI
Affinity DataKi: >5.26E+3nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222V3CPubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50211207(CHEMBL3950038)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Antagonist activity at human 5-HT3A expressed in HEK293 cells assessed as reduction in acetylcholine-induced activity preincubated for 30 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0X2HPubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50211210(CHEMBL3984925)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Antagonist activity at human 5-HT3A expressed in HEK293 cells assessed as reduction in acetylcholine-induced activity preincubated for 30 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0X2HPubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50211200(CHEMBL3974854)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Antagonist activity at human 5-HT3A expressed in HEK293 cells assessed as reduction in acetylcholine-induced activity preincubated for 30 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0X2HPubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50211198(CHEMBL3961219)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human 5-HT3A expressed in HEK293 cells assessed as reduction in acetylcholine-induced activity preincubated for 30 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0X2HPubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50211215(CHEMBL3898922)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Antagonist activity at human 5-HT3A expressed in HEK293 cells assessed as reduction in acetylcholine-induced activity preincubated for 30 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0X2HPubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50211212(CHEMBL3927589)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Antagonist activity at human 5-HT3A expressed in HEK293 cells assessed as reduction in acetylcholine-induced activity preincubated for 30 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0X2HPubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50211202(CHEMBL3981300)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Antagonist activity at human 5-HT3A expressed in HEK293 cells assessed as reduction in acetylcholine-induced activity preincubated for 30 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0X2HPubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50211196(CHEMBL3954179)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Antagonist activity at human 5-HT3A expressed in HEK293 cells assessed as reduction in acetylcholine-induced activity preincubated for 30 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0X2HPubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50211220(CHEMBL3970846)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Antagonist activity at human 5-HT3A expressed in HEK293 cells assessed as reduction in acetylcholine-induced activity preincubated for 30 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0X2HPubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50211211(CHEMBL3902912)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Antagonist activity at human 5-HT3A expressed in HEK293 cells assessed as reduction in acetylcholine-induced activity preincubated for 30 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0X2HPubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50211206(CHEMBL3923346)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Antagonist activity at human 5-HT3A expressed in HEK293 cells assessed as reduction in acetylcholine-induced activity preincubated for 30 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0X2HPubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50211208(CHEMBL3926969)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:Antagonist activity at human 5-HT3A expressed in HEK293 cells assessed as reduction in acetylcholine-induced activity preincubated for 30 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0X2HPubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50211097(CHEMBL3973872)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Antagonist activity at human 5-HT3A expressed in HEK293 cells assessed as reduction in acetylcholine-induced activity preincubated for 30 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0X2HPubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50206243(CHEMBL3918431)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Antagonist activity at human 5-HT3A expressed in HEK293 cells assessed as reduction in acetylcholine-induced activity preincubated for 30 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0X2HPubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50211197(CHEMBL3951064)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Antagonist activity at human 5-HT3A expressed in HEK293 cells assessed as reduction in acetylcholine-induced activity preincubated for 30 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0X2HPubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50211214(CHEMBL3934387)copy SMILEScopy InChI
Affinity DataIC50: 950nMAssay Description:Antagonist activity at human 5-HT3A expressed in HEK293 cells assessed as reduction in acetylcholine-induced activity preincubated for 30 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0X2HPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50211195(CHEMBL3944506)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0X2HPubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50206265(CHEMBL3909084)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Antagonist activity at human 5-HT3A expressed in HEK293 cells assessed as reduction in acetylcholine-induced activity preincubated for 30 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0X2HPubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50211217(CHEMBL3895986)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Antagonist activity at human 5-HT3A expressed in HEK293 cells assessed as reduction in acetylcholine-induced activity preincubated for 30 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0X2HPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50206243(CHEMBL3918431)copy SMILEScopy InChI
Affinity DataIC50: 3.22E+3nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0X2HPubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50211204(CHEMBL3972330)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+3nMAssay Description:Antagonist activity at human 5-HT3A expressed in HEK293 cells assessed as reduction in acetylcholine-induced activity preincubated for 30 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0X2HPubMed
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