Compile Data Set for Download or QSAR
Found 415 with Last Name = 'chu' and Initial = 'jc'
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50532101(CHEMBL4439408)copy SMILEScopy InChI
Affinity DataIC50: 0.0240nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52T3WPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50532101(CHEMBL4439408)copy SMILEScopy InChI
Affinity DataIC50: 0.0240nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52T3WPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50206900(CHEMBL3895181)copy SMILEScopy InChI
Affinity DataIC50: 0.0300nMAssay Description:Antagonist activity at GR in human HepG2 cells assessed as inhibition of protein mediated-transcriptional activity by MMTV-promoter driven luciferase...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B339QPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM368199((S)-2-(4-(2-(3-(fluoromethyl)azetidin-1-yl)ethoxy)...)copy SMILEScopy InChI
Affinity DataIC50: 0.0300nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50532103(CHEMBL4464224)copy SMILEScopy InChI
Affinity DataIC50: 0.0450nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50532105(CHEMBL4449709)copy SMILEScopy InChI
Affinity DataIC50: 0.0510nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52T3WPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50532102(CHEMBL4437985)copy SMILEScopy InChI
Affinity DataIC50: 0.0550nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50532098(CHEMBL4464058)copy SMILEScopy InChI
Affinity DataIC50: 0.0590nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGlucocorticoid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50206950(CHEMBL3933702)copy SMILEScopy InChI
Affinity DataIC50: 0.0700nMAssay Description:Antagonist activity at GR in human HepG2 cells assessed as inhibition of protein mediated-transcriptional activity by MMTV-promoter driven luciferase...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B339QPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50532106(CHEMBL4539802)copy SMILEScopy InChI
Affinity DataIC50: 0.0760nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52T3WPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50532104(CHEMBL1087419)copy SMILEScopy InChI
Affinity DataIC50: 0.280nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52T3WPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50206947(CHEMBL3966490)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Antagonist activity at GR in human HepG2 cells assessed as inhibition of protein mediated-transcriptional activity by MMTV-promoter driven luciferase...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B339QPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50206952(CHEMBL3907029)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Antagonist activity at GR in human HepG2 cells assessed as inhibition of protein mediated-transcriptional activity by MMTV-promoter driven luciferase...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B339QPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50206951(CHEMBL3904106)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at GR in human HepG2 cells assessed as inhibition of protein mediated-transcriptional activity by MMTV-promoter driven luciferase...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B339QPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50532099(CHEMBL4443826)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52T3WPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50532099(CHEMBL4443826)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52T3WPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50570668(CHEMBL4862510)copy SMILES
Affinity DataIC50: 4.60nMAssay Description:Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus-infected Sf9 cells using Boc-Lys (acetyl)-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TN4PubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50005596(CHEMBL3234622)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human HepG2 cells assessed as inhibition of 17beta-estradiol-induced transcriptional acti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3V9NPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50005603(CHEMBL3234630)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human HepG2 cells assessed as inhibition of 17beta-estradiol-induced transcriptional acti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3V9NPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50005598(CHEMBL3234626)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human HepG2 cells assessed as inhibition of 17beta-estradiol-induced transcriptional acti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3V9NPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50005588(CHEMBL140411 | CHEMBL3234614)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human HepG2 cells assessed as inhibition of 17beta-estradiol-induced transcriptional acti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3V9NPubMed
TargetEukaryotic translation initiation factor 2-alpha kinase 1(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50414894(CHEMBL573760)copy SMILEScopy InChI
Affinity DataIC50: 6.31nMAssay Description:Inhibition of human HRI kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZGZPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50005595(CHEMBL3234621)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human HepG2 cells assessed as inhibition of 17beta-estradiol-induced transcriptional acti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3V9NPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50517568(CHEMBL4438566)copy SMILEScopy InChI
Affinity DataIC50: 7.60nMAssay Description:Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus-infected Sf9 cells using Boc-Lys (acetyl)-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TN4PubMed
TargetEukaryotic translation initiation factor 2-alpha kinase 1(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50414893(CHEMBL578426)copy SMILEScopy InChI
Affinity DataIC50: 7.94nMAssay Description:Inhibition of human HRI kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZGZPubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50005593(CHEMBL3234619)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human HepG2 cells assessed as inhibition of 17beta-estradiol-induced transcriptional acti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3V9NPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50570667(CHEMBL4877300)copy SMILES
Affinity DataIC50: 9.40nMAssay Description:Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus-infected Sf9 cells using Boc-Lys (acetyl)-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TN4PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50517570(CHEMBL4530950)copy SMILEScopy InChI
Affinity DataIC50: 9.5nMAssay Description:Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus-infected Sf9 cells using Boc-Lys (acetyl)-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TN4PubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50532100(CHEMBL4464146)copy SMILEScopy InChI
Affinity DataIC50: 9.60nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52T3WPubMed
TargetEstrogen receptor(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50532100(CHEMBL4464146)copy SMILEScopy InChI
Affinity DataIC50: 9.60nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52T3WPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50570670(CHEMBL4874671)copy SMILES
Affinity DataIC50: 9.80nMAssay Description:Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus-infected Sf9 cells using Boc-Lys (acetyl)-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TN4PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50570669(CHEMBL4877805)copy SMILES
Affinity DataIC50: 11nMAssay Description:Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus-infected Sf9 cells using Boc-Lys (acetyl)-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TN4PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus-infected Sf9 cells using Boc-Lys (acetyl)-AMC as substrate prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TN4PubMedDrugBank
TargetEstrogen receptor beta(Homo sapiens (Human))
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50005587(CHEMBL138420 | CHEMBL3234612)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human HepG2 cells assessed as inhibition of 17beta-estradiol-induced transcriptional acti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3V9NPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50570674(CHEMBL4847771)copy SMILES
Affinity DataIC50: 14nMAssay Description:Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus-infected Sf9 cells using Boc-Lys (acetyl)-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TN4PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50517565(CHEMBL4472834)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus-infected Sf9 cells using Boc-Lys (acetyl)-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TN4PubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50005592(CHEMBL139628 | CHEMBL3234618)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human HepG2 cells assessed as inhibition of 17beta-estradiol-induced transcriptional acti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3V9NPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50570675(CHEMBL4846564)copy SMILES
Affinity DataIC50: 16nMAssay Description:Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus-infected Sf9 cells using Boc-Lys (acetyl)-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TN4PubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50005599(CHEMBL3234627)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human HepG2 cells assessed as inhibition of 17beta-estradiol-induced transcriptional acti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3V9NPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50517567(CHEMBL4545246)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus-infected Sf9 cells using Boc-Lys (acetyl)-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TN4PubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50005591(CHEMBL141807 | CHEMBL3234617)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human HepG2 cells assessed as inhibition of 17beta-estradiol-induced transcriptional acti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3V9NPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50570671(CHEMBL4877023)copy SMILES
Affinity DataIC50: 19nMAssay Description:Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus-infected Sf9 cells using Boc-Lys (acetyl)-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TN4PubMed
TargetEukaryotic translation initiation factor 2-alpha kinase 1(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50414892(CHEMBL576168)copy SMILEScopy InChI
Affinity DataIC50: 19.9nMAssay Description:Inhibition of human HRI kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZGZPubMed
TargetHistone deacetylase(Homo sapiens (Human))TBA
LigandPNGBDBM50570676(CHEMBL4859992)copy SMILES
Affinity DataIC50: 20nMAssay Description:Inhibition of HDAC in human HeLa nuclear extracts using Boc-Lys (acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TN4PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50517575(CHEMBL4473451)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus-infected Sf9 cells using Boc-Lys (acetyl)-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TN4PubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50005594(CHEMBL3234620)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human HepG2 cells assessed as inhibition of 17beta-estradiol-induced transcriptional acti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3V9NPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human C-terminal FLAG/His-tagged HDAC1 (1 to 482 residues) expressed in Sf9 insect cells using fluor de lys SIRT1 as substr...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50551540(CHEMBL4762873)copy SMILES
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 insect cells using Boc-Lys(Ac)-AMC as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7F3BPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50551544(CHEMBL4796066)copy SMILES
Affinity DataIC50: 26nMAssay Description:Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus-infected Sf9 cells using Boc-Lys (acetyl)-AMC as substrate prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TN4PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50551544(CHEMBL4796066)copy SMILES
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 insect cells using Boc-Lys(Ac)-AMC as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7F3BPubMed
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