Compile Data Set for Download or QSAR
Found 18 with Last Name = 'freedman' and Initial = 'jc'
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50417153(CHEMBL1270704)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human N-terminal His6-tagged 15-LOX-1 Q547L mutant expressed in sf9 cells using arachidonic acid as substrate by UV-Visible spectrophot...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28D00SJPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50417153(CHEMBL1270704)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of wild type human N-terminal His6-tagged 15-LOX-1 expressed in sf9 cells using arachidonic acid or linoleic acid as substrate by UV-Visib...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28D00SJPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50417153(CHEMBL1270704)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human N-terminal His6-tagged 15-LOX-1 R402L mutant expressed in sf9 cells using arachidonic acid or linoleic acid as substrate by UV-Vi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28D00SJPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50417153(CHEMBL1270704)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of human N-terminal His6-tagged 15-LOX-1 R404L mutant expressed in sf9 cells using arachidonic acid or linoleic acid as substrate by UV-Vi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28D00SJPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50417153(CHEMBL1270704)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of human N-terminal His6-tagged 15-LOX-1 I417A mutant expressed in sf9 cells using arachidonic acid or linoleic acid as substrate by UV-Vi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28D00SJPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50417153(CHEMBL1270704)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:Inhibition of human N-terminal His6-tagged 15-LOX-1 F414I mutant expressed in sf9 cells using arachidonic acid or linoleic acid as substrate by UV-Vi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28D00SJPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM79800(5-(methylamino)-2-(1-naphthalenyl)-4-oxazolecarbon...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of human N-terminal His6-tagged 15-LOX-1 R402L mutant expressed in sf9 cells using arachidonic acid or linoleic acid as substrate by UV-Vi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28D00SJPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50417153(CHEMBL1270704)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of human N-terminal His6-tagged 15-LOX-1 E356Q mutant expressed in sf9 cells using arachidonic acid as substrate by UV-Visible spectrophot...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28D00SJPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM79800(5-(methylamino)-2-(1-naphthalenyl)-4-oxazolecarbon...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of human N-terminal His6-tagged 15-LOX-1 I417A mutant expressed in sf9 cells using arachidonic acid or linoleic acid as substrate by UV-Vi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28D00SJPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50417153(CHEMBL1270704)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of human N-terminal His6-tagged 15-LOX-1 F414W mutant expressed in sf9 cells using arachidonic acid as substrate by UV-Visible spectrophot...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28D00SJPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM79800(5-(methylamino)-2-(1-naphthalenyl)-4-oxazolecarbon...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of human N-terminal His6-tagged 15-LOX-1 R404L mutant expressed in sf9 cells using arachidonic acid or linoleic acid as substrate by UV-Vi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28D00SJPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM79800(5-(methylamino)-2-(1-naphthalenyl)-4-oxazolecarbon...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of human N-terminal His6-tagged 15-LOX-1 Q547L mutant expressed in sf9 cells using arachidonic acid as substrate by UV-Visible spectrophot...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28D00SJPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM79800(5-(methylamino)-2-(1-naphthalenyl)-4-oxazolecarbon...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibition of wild type human N-terminal His6-tagged 15-LOX-1 expressed in sf9 cells using arachidonic acid or linoleic acid as substrate by UV-Visib...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28D00SJPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM79800(5-(methylamino)-2-(1-naphthalenyl)-4-oxazolecarbon...)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:Inhibition of human N-terminal His6-tagged 15-LOX-1 L407A mutant expressed in sf9 cells using arachidonic acid as substrate by UV-Visible spectrophot...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28D00SJPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM79800(5-(methylamino)-2-(1-naphthalenyl)-4-oxazolecarbon...)copy SMILEScopy InChI
Affinity DataIC50: 770nMAssay Description:Inhibition of human N-terminal His6-tagged 15-LOX-1 F414W mutant expressed in sf9 cells using arachidonic acid as substrate by UV-Visible spectrophot...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28D00SJPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM79800(5-(methylamino)-2-(1-naphthalenyl)-4-oxazolecarbon...)copy SMILEScopy InChI
Affinity DataIC50: 870nMAssay Description:Inhibition of human N-terminal His6-tagged 15-LOX-1 E356Q mutant expressed in sf9 cells using arachidonic acid as substrate by UV-Visible spectrophot...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28D00SJPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM79800(5-(methylamino)-2-(1-naphthalenyl)-4-oxazolecarbon...)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human N-terminal His6-tagged 15-LOX-1 F414I mutant expressed in sf9 cells using arachidonic acid or linoleic acid as substrate by UV-Vi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28D00SJPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50417153(CHEMBL1270704)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human N-terminal His6-tagged 15-LOX-1 L407A mutant expressed in sf9 cells using arachidonic acid as substrate by UV-Visible spectrophot...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28D00SJPubMed