Compile Data Set for Download or QSAR
Found 733 with Last Name = 'semple' and Initial = 'je'
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50111741(CHEMBL19666 | N-(5-Carbamimidoyl-thiophen-2-ylmeth...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0FGBPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50111728(4-Fluoro-2-({1-[((R)-1-formyl-4-guanidino-butylcar...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0FGBPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50111729(CHEMBL277695 | N-(5-Carbamimidoyl-thiophen-2-ylmet...)copy SMILEScopy InChI
Affinity DataKi:  0.120nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0FGBPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50111730(2-[3-(2-Fluoro-phenylmethanesulfonylamino)-6-methy...)copy SMILEScopy InChI
Affinity DataKi:  0.140nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0FGBPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50111724(CHEMBL19731 | N-(4-Carbamimidoyl-benzyl)-2-(6-meth...)copy SMILEScopy InChI
Affinity DataKi:  0.370nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0FGBPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50110382(P1 argininal derivative | [amino({[(4S)-4-carboxy-...)copy SMILEScopy InChI
Affinity DataKi:  0.540nMAssay Description:Inhibitory constant against human thrombin (FIIa) determined in vitroMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B0319PubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50111717(2-[3-(2-Fluoro-phenylmethanesulfonylamino)-2-oxo-2...)copy SMILEScopy InChI
Affinity DataKi:  0.560nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0FGBPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50111726(CHEMBL19359 | N-(4-Carbamimidoyl-benzyl)-2-(6-meth...)copy SMILEScopy InChI
Affinity DataKi:  0.570nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0FGBPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50110393(5-{3-[(S)-3-(2,3-Dihydro-benzofuran-5-sulfonylamin...)copy SMILEScopy InChI
Affinity DataKi:  0.600nMAssay Description:Inhibitory constant against human thrombin (FIIa) determined in vitroMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B0319PubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50067796(CHEMBL11157 | L-374087 | N-((6-amino-2-methylpyrid...)copy SMILEScopy InChI
Affinity DataKi:  0.680nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0FGBPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50067796(CHEMBL11157 | L-374087 | N-((6-amino-2-methylpyrid...)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27946WJPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50110394(P1 argininal derivative | [amino({[(4S)-4-carboxy-...)copy SMILEScopy InChI
Affinity DataKi:  0.950nMAssay Description:Inhibitory constant against human thrombin (FIIa) determined in vitroMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B0319PubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50067797(CHEMBL19080 | L-37378 | N-(6-Amino-2-methyl-pyridi...)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0FGBPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50067797(CHEMBL19080 | L-37378 | N-(6-Amino-2-methyl-pyridi...)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27946WJPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50111739(CHEMBL19811 | N-((S)-2-Amino-1,4,5,6-tetrahydro-py...)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0FGBPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50081158(2-((R)-3-Amino-3-benzyl-2-oxo-piperidin-1-yl)-N-((...)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Evaluation of inhibition of transition state thrombinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8D3WPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50071693(CHEMBL38927 | CVS-1578 | N-((S)-1-Carbamimidoyl-2-...)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Evaluation of inhibition of transition state thrombinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8D3WPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50081157((S)-1-[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-...)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Evaluation of inhibition of transition state thrombinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8D3WPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50054502(CHEMBL140494 | N-((S)-3-Carbamimidoyl-2-hydroxy-cy...)copy SMILEScopy InChI
Affinity DataKi:  1.01nMAssay Description:compound was tested in vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28051QTPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50111738(CHEMBL274968 | N-((4R,5S)-2-Amino-4-methyl-1,4,5,6...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0FGBPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50111714(CHEMBL416912 | N-(4-Carbamimidoyl-2-methoxy-benzyl...)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0FGBPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50111742(CHEMBL417635 | N-((S)-2-Amino-1,4,5,6-tetrahydro-p...)copy SMILEScopy InChI
Affinity DataKi:  1.90nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0FGBPubMed
TargetTrypsin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50110387(4-{2-[(S)-5-((S)-2,3-Dihydro-benzofuran-5-sulfonyl...)copy SMILEScopy InChI
Affinity DataKi:  2.5nMAssay Description:Inhibitory constant against trypsin determined in VitroMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B0319PubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50215314(CHEMBL100049)copy SMILEScopy InChI
Affinity DataKi:  2.5nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27946WJPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50215447(CHEMBL101867)copy SMILEScopy InChI
Affinity DataKi:  2.90nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27946WJPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50100973(CHEMBL101605)copy SMILEScopy InChI
Affinity DataKi:  3.10nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27946WJPubMed
TargetTrypsin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50110389(4-{3-[(S)-3-(2,3-Dihydro-benzofuran-5-sulfonylamin...)copy SMILEScopy InChI
Affinity DataKi:  3.20nMAssay Description:Inhibitory constant against trypsin determined in VitroMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B0319PubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50111736(CHEMBL19548 | N-((4R,5S)-2-Amino-4-methyl-1,4,5,6-...)copy SMILEScopy InChI
Affinity DataKi:  3.20nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0FGBPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50111720(CHEMBL19619 | N-(4-Carbamimidoyl-3-fluoro-benzyl)-...)copy SMILEScopy InChI
Affinity DataKi:  3.60nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0FGBPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50215308(CHEMBL99185)copy SMILEScopy InChI
Affinity DataKi:  3.90nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27946WJPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50105480(CHEMBL98194)copy SMILEScopy InChI
Affinity DataKi:  4.10nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27946WJPubMed
TargetSerine protease 1(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50111729(CHEMBL277695 | N-(5-Carbamimidoyl-thiophen-2-ylmet...)copy SMILEScopy InChI
Affinity DataKi:  4.40nMAssay Description:In vitro inhibitory constant against trypsinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0FGBPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50215441(CHEMBL101562)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27946WJPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50111732(CHEMBL19453 | N-(4-Carbamimidoyl-benzyl)-2-[3-(3-m...)copy SMILEScopy InChI
Affinity DataKi:  5.30nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0FGBPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50111725(CHEMBL19689 | N-(5-Amino-pyrazin-2-ylmethyl)-2-(3-...)copy SMILEScopy InChI
Affinity DataKi:  5.5nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0FGBPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50100974(CHEMBL317739)copy SMILEScopy InChI
Affinity DataKi:  5.70nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27946WJPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50111731(CHEMBL19740 | N-(5-Amino-pyrazin-2-ylmethyl)-2-{3-...)copy SMILEScopy InChI
Affinity DataKi:  5.90nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0FGBPubMed
TargetTrypsin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50110393(5-{3-[(S)-3-(2,3-Dihydro-benzofuran-5-sulfonylamin...)copy SMILEScopy InChI
Affinity DataKi:  5.90nMAssay Description:Inhibitory constant against trypsin determined in VitroMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B0319PubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50111716(CHEMBL19798 | N-(4-Carbamimidoyl-thiazol-2-ylmethy...)copy SMILEScopy InChI
Affinity DataKi:  5.90nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0FGBPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50111718(CHEMBL279199 | N-(4-Carbamimidoyl-2-fluoro-benzyl)...)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0FGBPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50110389(4-{3-[(S)-3-(2,3-Dihydro-benzofuran-5-sulfonylamin...)copy SMILEScopy InChI
Affinity DataKi:  6.20nMAssay Description:Inhibitory constant against human thrombin (FIIa) determined in vitroMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B0319PubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50215310(CHEMBL97869)copy SMILEScopy InChI
Affinity DataKi:  6.5nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27946WJPubMed
TargetTrypsin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50110374(4-{3-[(S)-3-(2,3-Dihydro-benzofuran-5-sulfonylamin...)copy SMILEScopy InChI
Affinity DataKi:  7.60nMAssay Description:Inhibitory constant against trypsin determined in VitroMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B0319PubMed
TargetTrypsin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50110391(4-[3-((S)-3-Benzenesulfonylamino-2-oxo-azepan-1-yl...)copy SMILEScopy InChI
Affinity DataKi:  8.30nMAssay Description:Inhibitory constant against trypsin determined in VitroMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B0319PubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50215311(CHEMBL317140)copy SMILEScopy InChI
Affinity DataKi:  9nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27946WJPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50110386(4-{3-[(S)-3-(2,5-Dimethoxy-benzenesulfonylamino)-2...)copy SMILEScopy InChI
Affinity DataKi:  9nMAssay Description:Inhibitory constant against human thrombin (FIIa) determined in vitroMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B0319PubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50100975(CHEMBL100838)copy SMILEScopy InChI
Affinity DataKi:  9.30nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27946WJPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50111746(CHEMBL282028 | N-(5-Amino-pyrazin-2-ylmethyl)-2-[3...)copy SMILEScopy InChI
Affinity DataKi:  9.80nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0FGBPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50215302(CHEMBL98057)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27946WJPubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International, Inc.

Curated by ChEMBL
LigandPNGBDBM50216995(CHEMBL319815)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27946WJPubMed
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