Compile Data Set for Download or QSAR
Found 213 with Last Name = 'shin' and Initial = 'je'
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM144315(Gilteritinib | US11512074, Example T-9 | US8969336...)copy SMILEScopy InChI
Affinity DataIC50: 0.290nMAssay Description:Inhibition of FLT3 expressed in human SEMK2 cells assessed as reduction in FLT3 phosphorylation incubated for 1 hr by immunoblotting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4H1RPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM50564363(CHEMBL4791998)copy SMILES
Affinity DataIC50: 0.320nMAssay Description:Inhibition of human FLT3 D835Y mutant in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4H1RPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM50564363(CHEMBL4791998)copy SMILES
Affinity DataIC50: 0.870nMAssay Description:Inhibition of recombinant His-tagged human FLT3 expressed in baculovirus expression system using peptide substrate incubated for 30 mins in presence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4H1RPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of FLT3 autophosphorylation in human RS4-11 cells preincubated for 2 hrs followed by FLT3 ligand addition and measured after 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4H1RPubMed
LigandPNGBDBM50564363(CHEMBL4791998)copy SMILES
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human RET in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4H1RPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM185149(1-[2-[5-[(3-methyloxetan-3-yl)methoxy]benzimidazol...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4H1RPubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50564363(CHEMBL4791998)copy SMILES
Affinity DataIC50: 2nMAssay Description:Inhibition of human TrkB in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4H1RPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM50564373(CHEMBL4093032)copy SMILES
Affinity DataIC50: 2.10nMAssay Description:Inhibition of recombinant His-tagged human FLT3 expressed in baculovirus expression system using peptide substrate incubated for 30 mins in presence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4H1RPubMed
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