Compile Data Set for Download or QSAR
Found 163 with Last Name = 'souness' and Initial = 'je'
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataKi:  4.5nMAssay Description:Inhibition of rolipram binding to Phosphodiesterase 4More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50064858((R)-4-(2-(3-(cyclopentyloxy)-4-methoxyphenyl)-2-ph...)copy SMILEScopy InChI
Affinity DataKi:  60nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0PTSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50216308(CHEMBL297296)copy SMILEScopy InChI
Affinity DataKi:  200nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0PTSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50216314(CHEMBL49351)copy SMILEScopy InChI
Affinity DataKi:  2.40E+3nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0PTSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50216313(CHEMBL300959)copy SMILEScopy InChI
Affinity DataKi:  2.60E+3nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0PTSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50216322(CHEMBL301351)copy SMILEScopy InChI
Affinity DataKi:  2.80E+3nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0PTSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50216320(CHEMBL430948)copy SMILEScopy InChI
Affinity DataKi: >3.70E+3nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0PTSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50216309(CHEMBL301366)copy SMILEScopy InChI
Affinity DataKi: >3.70E+3nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0PTSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50216312(CHEMBL296824)copy SMILEScopy InChI
Affinity DataKi: >3.70E+3nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0PTSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50216311(CHEMBL300427)copy SMILEScopy InChI
Affinity DataKi: >3.70E+3nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0PTSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50216310(CHEMBL52224)copy SMILEScopy InChI
Affinity DataKi: >3.70E+3nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0PTSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50216306(CHEMBL48221)copy SMILEScopy InChI
Affinity DataKi: >3.70E+3nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0PTSPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50216307(CHEMBL300038)copy SMILEScopy InChI
Affinity DataKi: >3.70E+3nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0PTSPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Aventis Pharma S.A.

Curated by ChEMBL
LigandPNGBDBM50473625(CHEMBL69319)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of p38-related TNF alpha release by human monocyte cell line (THP-1)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7MFKPubMed
Target3',5'-cyclic-AMP phosphodiesterase(Sus scrofa)
Rhône-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50041849(3-(Bicyclo[2.2.1]hept-2-yloxy)-N-(3,5-dichloro-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CF9P5FPubMed
Target3',5'-cyclic-AMP phosphodiesterase(Sus scrofa)
Rhône-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50041849(3-(Bicyclo[2.2.1]hept-2-yloxy)-N-(3,5-dichloro-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CF9P5FPubMed
Target3',5'-cyclic-AMP phosphodiesterase(Sus scrofa)
Rhône-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CF9P5FPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Aventis Pharma S.A.

Curated by ChEMBL
LigandPNGBDBM50473629(CHEMBL70053 | RPR-238677)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of p38-related TNF alpha release by human monocyte cell line (THP-1)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7MFKPubMed
Target3',5'-cyclic-AMP phosphodiesterase(Sus scrofa)
Rhône-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50041853(3-Cyclopentyloxy-N-(3,5-dichloro-1-oxy-pyridin-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CF9P5FPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Aventis Pharma S.A.

Curated by ChEMBL
LigandPNGBDBM50473626(CHEMBL71572 | RPR-239938)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of p38-related TNF alpha release by human monocyte cell line (THP-1)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7MFKPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Aventis Pharma S.A.

Curated by ChEMBL
LigandPNGBDBM50473627(CHEMBL308203 | RPR-239939)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibition of p38-related TNF alpha release by human monocyte cell line (THP-1)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7MFKPubMed
TargetMitogen-activated protein kinase 13(Mus musculus)
Aventis Pharma S.A.

Curated by ChEMBL
LigandPNGBDBM50473623(CHEMBL309802 | RPR-238778)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7MFKPubMed
TargetMitogen-activated protein kinase 13(Mus musculus)
Aventis Pharma S.A.

Curated by ChEMBL
LigandPNGBDBM50473629(CHEMBL70053 | RPR-238677)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7MFKPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50064858((R)-4-(2-(3-(cyclopentyloxy)-4-methoxyphenyl)-2-ph...)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:Inhibition of guinea pig macrophage Phosphodiesterase 4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0PTSPubMed
TargetMitogen-activated protein kinase 13(Mus musculus)
Aventis Pharma S.A.

Curated by ChEMBL
LigandPNGBDBM50219254(CHEMBL347592)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F191WGPubMed
TargetMitogen-activated protein kinase 13(Mus musculus)
Aventis Pharma S.A.

Curated by ChEMBL
LigandPNGBDBM50473632(CHEMBL71425 | RPR-239457)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7MFKPubMed
TargetMitogen-activated protein kinase 13(Mus musculus)
Aventis Pharma S.A.

Curated by ChEMBL
LigandPNGBDBM50473626(CHEMBL71572 | RPR-239938)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7MFKPubMed
TargetMitogen-activated protein kinase 13(Mus musculus)
Aventis Pharma S.A.

Curated by ChEMBL
LigandPNGBDBM50473627(CHEMBL308203 | RPR-239939)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7MFKPubMed
TargetMitogen-activated protein kinase 13(Mus musculus)
Aventis Pharma S.A.

Curated by ChEMBL
LigandPNGBDBM50473625(CHEMBL69319)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7MFKPubMed
Target3',5'-cyclic-AMP phosphodiesterase(Sus scrofa)
Rhône-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50041831(3-Cyclopentyloxy-N-(3,5-dibromo-pyridin-4-yl)-4-me...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CF9P5FPubMed
TargetMitogen-activated protein kinase 13(Mus musculus)
Aventis Pharma S.A.

Curated by ChEMBL
LigandPNGBDBM50219252(CHEMBL159932)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F191WGPubMed
Target3',5'-cyclic-AMP phosphodiesterase(Sus scrofa)
Rhône-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50041846(3-Butoxy-N-(3,5-dichloro-pyridin-4-yl)-4-methoxy-b...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CF9P5FPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Aventis Pharma S.A.

Curated by ChEMBL
LigandPNGBDBM50473623(CHEMBL309802 | RPR-238778)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of p38-related TNF alpha release by human monocyte THP-1 cell linesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7MFKPubMed
TargetMitogen-activated protein kinase 13(Mus musculus)
Aventis Pharma S.A.

Curated by ChEMBL
LigandPNGBDBM50219253(CHEMBL161197)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F191WGPubMed
Target3',5'-cyclic-AMP phosphodiesterase(Sus scrofa)
Rhône-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50041886(3-(Bicyclo[2.2.1]hept-2-yloxy)-N-(2,6-dichloro-phe...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CF9P5FPubMed
TargetMitogen-activated protein kinase 13(Mus musculus)
Aventis Pharma S.A.

Curated by ChEMBL
LigandPNGBDBM50473622(CHEMBL70705 | RPR-239497)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7MFKPubMed
Target3',5'-cyclic-AMP phosphodiesterase(Sus scrofa)
Rhône-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50041847(CHEMBL295976 | N-(3-Chloro-pyridin-4-yl)-3-cyclope...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CF9P5FPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Mus musculus)
Aventis Pharma

Curated by ChEMBL
LigandPNGBDBM50219251(CHEMBL423071)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against p38 kinase (40 ng/well) was determined in mouseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F191WGPubMed
Target3',5'-cyclic-AMP phosphodiesterase(Sus scrofa)
Rhône-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50041875(3-Cyclopentyloxy-N-(3,5-dichloro-2,6-difluoro-pyri...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CF9P5FPubMed
Target3',5'-cyclic-AMP phosphodiesterase(Sus scrofa)
Rhône-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50041838(3-(cyclopentyloxy)-N-(2,6-dichlorophenyl)-4-methox...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CF9P5FPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132421(3-[1-(1H-Pyrrol-2-yl)-meth-(Z)-ylidene]-5-(thiophe...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibitory activity against Janus Kinase 3 protein tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2833RDRPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132420(3-((1H-pyrrol-2-yl)methylene)-5-(pyridin-3-yl)indo...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibitory activity against Janus Kinase 3 protein tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2833RDRPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132427(5-Pyridin-3-yl-3-[1-(1H-pyrrol-2-yl)-meth-(Z)-ylid...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against Janus Kinase 3 protein tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2833RDRPubMed
Target3',5'-cyclic-AMP phosphodiesterase(Sus scrofa)
Rhône-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50041869(3-Cyclopentyloxy-N-(3,5-dimethyl-pyridin-4-yl)-4-m...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CF9P5FPubMed
TargetMitogen-activated protein kinase 13(Mus musculus)
Aventis Pharma S.A.

Curated by ChEMBL
LigandPNGBDBM50473630(CHEMBL67911 | RPR-235455)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7MFKPubMed
Target3',5'-cyclic-AMP phosphodiesterase(Sus scrofa)
Rhône-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50041824(3-Cyclohexyloxy-N-(3,5-dichloro-pyridin-4-yl)-4-me...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CF9P5FPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Aventis Pharma S.A.

Curated by ChEMBL
LigandPNGBDBM50473631(CHEMBL308003 | RPR-200765A)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of p38-related TNF alpha release by human monocyte cell line (THP-1)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7MFKPubMed
TargetMitogen-activated protein kinase 13(Mus musculus)
Aventis Pharma S.A.

Curated by ChEMBL
LigandPNGBDBM50473628(CHEMBL307604 | RPR-235315)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7MFKPubMed
Target3',5'-cyclic-AMP phosphodiesterase(Sus scrofa)
Rhône-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50041879(3-Butoxy-N-(3,5-dibromo-pyridin-4-yl)-4-methoxy-be...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CF9P5FPubMed
Target3',5'-cyclic-AMP phosphodiesterase(Sus scrofa)
Rhône-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50041844(3-(cyclopentyloxy)-N-(2,6-difluorophenyl)-4-methox...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CF9P5FPubMed
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