Compile Data Set for Download or QSAR
Found 89 with Last Name = 'liu' and Initial = 'jf'
TargetHistone deacetylase 6(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50439674(RICOLINOSTAT | US10858323, Compound 2 | US11207431...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac) (379 to 382) p53 peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28917F9PubMed
TargetBone morphogenetic protein 4(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50262079(4-(6-(4-(piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMAssay Description:Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8S0VPubMed
TargetBone morphogenetic protein 4(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50262178(4-(6-(4-(piperazin-1-yl)phenyl)H-pyrazolo[1,5-a]py...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8S0VPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50015233(CHEMBL3262727)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac) (379 to 382) p53 peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28917F9PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 9.40nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac) (379 to 382) p53 peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28917F9PubMedDrugBank
TargetBone morphogenetic protein 4(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50262017(4-(6-(4-(2-(4-methylpiperazin-1-yl)ethoxy)phenyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8S0VPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM100152(7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of DYRK1AMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50439674(RICOLINOSTAT | US10858323, Compound 2 | US11207431...)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of HDAC2 (unknown origin) using RHKK(Ac) (379 to 382) p53 peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28917F9PubMed
TargetBone morphogenetic protein 4(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50262016(4-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8S0VPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50439674(RICOLINOSTAT | US10858323, Compound 2 | US11207431...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibition of HDAC1 (unknown origin) using RHKK(Ac) (379 to 382) p53 peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28917F9PubMed
TargetBone morphogenetic protein 4(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50262018(4-(6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)pyrazolo[...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8S0VPubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379521(CHEMBL2012574)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of HDAC1 (unknown origin) using RHKK(Ac) (379 to 382) p53 peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetBone morphogenetic protein 4(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50262177(4-(6-(4-methoxyphenyl)H-pyrazolo[1,5-a]pyridin-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8S0VPubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379526(CHEMBL2012563)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379512(CHEMBL2012559)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379525(CHEMBL2012562)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379516(CHEMBL2012569)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379522(CHEMBL2012575)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetBone morphogenetic protein 4(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50262078(4-(3-(quinolin-4-yl)pyrazolo[1,5-a]pyrimidin-6-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8S0VPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50015235(CHEMBL3262725)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac) (379 to 382) p53 peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28917F9PubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379511(CHEMBL2012560)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50015233(CHEMBL3262727)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibition of HDAC1 (unknown origin) using RHKK(Ac) (379 to 382) p53 peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28917F9PubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379519(CHEMBL2012572)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetBone morphogenetic protein 4(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50262127(7-chloro-4-(6-(4-(piperazin-1-yl)phenyl)pyrazolo[1...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8S0VPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Inhibition of HDAC2 (unknown origin) using RHKK(Ac) (379 to 382) p53 peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetBone morphogenetic protein 4(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50262685(6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 430nMAssay Description:Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8S0VPubMed
TargetBone morphogenetic protein 4(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50261871(6-(4-(2-(4-methylpiperazin-1-yl)ethoxy)phenyl)-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 450nMAssay Description:Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8S0VPubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379524(CHEMBL2012561)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379523(CHEMBL2012558)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379520(CHEMBL2012573)copy SMILEScopy InChI
Affinity DataIC50: 470nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379517(CHEMBL2012570)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetBone morphogenetic protein 4(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50262081(7-chloro-4-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8S0VPubMed
TargetBone morphogenetic protein 4(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50261870(CHEMBL511216 | N,N-diethyl-2-(4-(3-(pyridin-4-yl)p...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8S0VPubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379527(CHEMBL2012564)copy SMILEScopy InChI
Affinity DataIC50: 580nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM100152(7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...)copy SMILEScopy InChI
Affinity DataIC50: 590nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379528(CHEMBL2012565)copy SMILEScopy InChI
Affinity DataIC50: 690nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM100152(7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...)copy SMILEScopy InChI
Affinity DataIC50: 690nMAssay Description:Inhibition of DYRK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetBone morphogenetic protein 4(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50262020(4-(6-phenylpyrazolo[1,5-a]pyrimidin-3-yl)quinoline...)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8S0VPubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50778((1S,2S,3R,8aS)-6-acetyl-3-carbamoyl-1-cyano-2-(3-t...)copy SMILEScopy InChI
Affinity DataIC50: 770nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379518(CHEMBL2012571)copy SMILEScopy InChI
Affinity DataIC50: 830nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50015233(CHEMBL3262727)copy SMILEScopy InChI
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of HDAC2 (unknown origin) using RHKK(Ac) (379 to 382) p53 peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28917F9PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50015233(CHEMBL3262727)copy SMILEScopy InChI
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28917F9PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50778((1S,2S,3R,8aS)-6-acetyl-3-carbamoyl-1-cyano-2-(3-t...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of DYRK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetBone morphogenetic protein 4(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM5416(4-(2-{4-[3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8S0VPubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379515(CHEMBL2012568)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetBone morphogenetic protein 4(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50262130(4-(3-(4-(2-(piperidin-1-yl)ethoxy)phenyl)H-pyrrolo...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8S0VPubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379514(CHEMBL2012567)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetBone morphogenetic protein 4(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50261979(5-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8S0VPubMed
TargetBone morphogenetic protein 4(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50261976(3-(3-fluoropyridin-4-yl)-6-(4-(2-(4-methylpiperazi...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8S0VPubMed
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