Compile Data Set for Download or QSAR
Found 175 with Last Name = 'martini' and Initial = 'jf'
LigandPNGBDBM104963(CHEMBL507361 | US11147816, PD0325901 | US11701360,...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402421(CHEMBL2208035)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
LigandPNGBDBM50391802((3,4-difluoro-2-(2-fluoro-4-iodophenylamino)phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402413(CHEMBL2208032)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
LigandPNGBDBM50391804(CHEMBL2146893)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5P80PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402409(CHEMBL2208034)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402412(CHEMBL2208033)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50310998(CHEMBL1077458 | N-(4-(2-(4-morpholinophenylamino)p...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
LigandPNGBDBM50391802((3,4-difluoro-2-(2-fluoro-4-iodophenylamino)phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of MEK1 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402416(CHEMBL2208025)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402424(CHEMBL2208027)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
LigandPNGBDBM50391805(CHEMBL2146894)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5P80PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402415(CHEMBL2208028)copy SMILEScopy InChI
Affinity DataIC50: 5.10nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
LigandPNGBDBM50391811(CHEMBL2146895)copy SMILEScopy InChI
Affinity DataIC50: 5.10nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5P80PubMed
LigandPNGBDBM50391800(CHEMBL2146898)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5P80PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402411(CHEMBL2207759)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402420(CHEMBL2207758)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402417(CHEMBL2208024)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
LigandPNGBDBM50391803(CHEMBL2146888)copy SMILEScopy InChI
Affinity DataIC50: 6.60nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402427(CHEMBL2207766)copy SMILEScopy InChI
Affinity DataIC50: 6.90nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
LigandPNGBDBM50391801(CHEMBL2146892)copy SMILEScopy InChI
Affinity DataIC50: 7.20nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5P80PubMed
LigandPNGBDBM50391808(CHEMBL2146896)copy SMILEScopy InChI
Affinity DataIC50: 7.60nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5P80PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402414(CHEMBL2208031)copy SMILEScopy InChI
Affinity DataIC50: 8.70nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402410(CHEMBL2207760)copy SMILEScopy InChI
Affinity DataIC50: 9.10nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402426(CHEMBL2207767)copy SMILEScopy InChI
Affinity DataIC50: 11.1nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402419(CHEMBL2207764)copy SMILEScopy InChI
Affinity DataIC50: 12.6nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402418(CHEMBL2208023)copy SMILEScopy InChI
Affinity DataIC50: 12.8nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
LigandPNGBDBM50391806(CHEMBL2146899)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5P80PubMed
LigandPNGBDBM50391812(CHEMBL2146885)copy SMILEScopy InChI
Affinity DataIC50: 19.5nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5P80PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Exelixis Inc

Curated by ChEMBL
LigandPNGBDBM50486034(CHEMBL2204501)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Displacement of biotinylated geldanamycin from human His-tagged Hsp90 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68KKPubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Exelixis Inc

Curated by ChEMBL
LigandPNGBDBM50486035(CHEMBL2204498)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Displacement of biotinylated geldanamycin from human His-tagged Hsp90 by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68KKPubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Exelixis Inc

Curated by ChEMBL
LigandPNGBDBM50486033(CHEMBL2204502)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Displacement of biotinylated geldanamycin from human His-tagged Hsp90 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68KKPubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Exelixis Inc

Curated by ChEMBL
LigandPNGBDBM50486032(CHEMBL2204497)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Displacement of biotinylated geldanamycin from human His-tagged Hsp90 by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68KKPubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Exelixis Inc

Curated by ChEMBL
LigandPNGBDBM50486036(CHEMBL2204496)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Displacement of biotinylated geldanamycin from human His-tagged Hsp90 by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68KKPubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Exelixis Inc

Curated by ChEMBL
LigandPNGBDBM50486041(CHEMBL2204500)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Displacement of biotinylated geldanamycin from human His-tagged Hsp90 by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68KKPubMed
LigandPNGBDBM50391797(CHEMBL2146890)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5P80PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Exelixis Inc

Curated by ChEMBL
LigandPNGBDBM50486042(CHEMBL2204499)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Displacement of biotinylated geldanamycin from human His-tagged Hsp90 by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68KKPubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Exelixis Inc

Curated by ChEMBL
LigandPNGBDBM50486043(CHEMBL2204504)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Displacement of biotinylated geldanamycin from human His-tagged Hsp90 by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68KKPubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Exelixis Inc

Curated by ChEMBL
LigandPNGBDBM50486037(CHEMBL2204503)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Displacement of biotinylated geldanamycin from human His-tagged Hsp90 by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68KKPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402423(CHEMBL2208029)copy SMILEScopy InChI
Affinity DataIC50: 39.6nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Exelixis Inc

Curated by ChEMBL
LigandPNGBDBM50486038(CHEMBL2204525)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Displacement of biotinylated geldanamycin from human His-tagged Hsp90 by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68KKPubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Exelixis Inc

Curated by ChEMBL
LigandPNGBDBM50486045(CHEMBL2204520)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of Hsp90 in human A549 cells assessed as Raf1 degradation after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68KKPubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Exelixis Inc

Curated by ChEMBL
LigandPNGBDBM50486043(CHEMBL2204504)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of Hsp90 in human NCI-N87 cells assessed as Her2 degradation after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68KKPubMed
LigandPNGBDBM50391809(CHEMBL2146887)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Exelixis Inc

Curated by ChEMBL
LigandPNGBDBM50486037(CHEMBL2204503)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of Hsp90 in human NCI-N87 cells assessed as Her2 degradation after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68KKPubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Exelixis Inc

Curated by ChEMBL
LigandPNGBDBM50486052(CHEMBL2204518)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Displacement of biotinylated geldanamycin from human His-tagged Hsp90 by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68KKPubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Exelixis Inc

Curated by ChEMBL
LigandPNGBDBM50486033(CHEMBL2204502)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of Hsp90 in human NCI-N87 cells assessed as Her2 degradation after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68KKPubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Exelixis Inc

Curated by ChEMBL
LigandPNGBDBM50486046(CHEMBL2204519)copy SMILEScopy InChI
Affinity DataIC50: 59nMAssay Description:Inhibition of Hsp90 in human A549 cells assessed as Raf1 degradation after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68KKPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402421(CHEMBL2208035)copy SMILEScopy InChI
Affinity DataIC50: 61.7nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ59ZNPubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Exelixis Inc

Curated by ChEMBL
LigandPNGBDBM50486045(CHEMBL2204520)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Displacement of biotinylated geldanamycin from human His-tagged Hsp90 by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68KKPubMed
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