Compile Data Set for Download or QSAR
Found 45 with Last Name = 'cannon' and Initial = 'jg'
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
College of Pharmacy University of Iowa

Curated by ChEMBL
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)copy SMILEScopy InChI
Affinity DataKi:  0.0450nMAssay Description:Binding affinity of compound against Dopamine receptor D2 binding site using radioligand [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q237799CPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
College of Pharmacy University of Iowa

Curated by ChEMBL
LigandPNGBDBM21393(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)copy SMILEScopy InChI
Affinity DataKi:  2.10nMAssay Description:Binding affinity of compound against 5-hydroxytryptamine 1A receptor binding site using radioligand [3H]8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q237799CPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
College of Pharmacy University of Iowa

Curated by ChEMBL
LigandPNGBDBM50017514(8,11-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dib...)copy SMILEScopy InChI
Affinity DataKi:  8.60nMAssay Description:Binding affinity of compound against 5-hydroxytryptamine 1A receptor binding site using radioligand [3H]8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q237799CPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
College of Pharmacy University of Iowa

Curated by ChEMBL
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Binding affinity of compound against 5-hydroxytryptamine 1A receptor binding site using radioligand [3H]8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q237799CPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
College of Pharmacy University of Iowa

Curated by ChEMBL
LigandPNGBDBM50017514(8,11-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dib...)copy SMILEScopy InChI
Affinity DataKi:  210nMAssay Description:Binding affinity of compound against Dopamine receptor D2 binding site using radioligand [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q237799CPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
College of Pharmacy University of Iowa

Curated by ChEMBL
LigandPNGBDBM50017513(8,11-Dimethoxy-6-propyl-5,6,6a,7-tetrahydro-4H-dib...)copy SMILEScopy InChI
Affinity DataKi:  240nMAssay Description:Binding affinity of compound against 5-hydroxytryptamine 1A receptor binding site using radioligand [3H]8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q237799CPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
College of Pharmacy University of Iowa

Curated by ChEMBL
LigandPNGBDBM50017513(8,11-Dimethoxy-6-propyl-5,6,6a,7-tetrahydro-4H-dib...)copy SMILEScopy InChI
Affinity DataKi:  770nMAssay Description:Binding affinity of compound against Dopamine receptor D2 binding site using radioligand [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q237799CPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
College of Pharmacy University of Iowa

Curated by ChEMBL
LigandPNGBDBM21393(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)copy SMILEScopy InChI
Affinity DataKi:  3.50E+3nMAssay Description:Binding affinity of compound against Dopamine receptor D2 binding site using radioligand [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q237799CPubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50368271(CHEMBL1204112)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Concentration required to inhibit hydrolytic activity of bovine erythrocyte acetylcholinesterase by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TK2PubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Concentration required to inhibit hydrolytic activity of Acetylcholinesterase by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TK2PubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50313079(3-Dimethylcarbamoyloxy-1-methyl-pyridinium; bromid...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Concentration required to inhibit hydrolytic activity of bovine erythrocyte acetylcholinesterase by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TK2PubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Inhibitory binding activity against dopamine receptor using [3H]ADTN as the radioligand in striatal tissue of calf brain.More data for this Ligand-Target Pair
TargetD(1A)/D(2) dopamine receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)copy SMILEScopy InChI
Affinity DataIC50: 830nMAssay Description:Inhibitory binding activity against dopamine receptor using [3H]ADTN as the radioligand in striatal tissue of calf brain.More data for this Ligand-Target Pair
TargetD(1A)/D(2) dopamine receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50224035(79907 | Lergotrile)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibitory binding activity against dopamine receptor using [3H]ADTN as the radioligand in striatal tissue of calf brain.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XD13WDPubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50223956(CHEMBL555412)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory binding activity against dopamine receptor using [3H]ADTN as the radioligand in striatal tissue of calf brain.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XD13WDPubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50368269(CHEMBL1202156)copy SMILEScopy InChI
Affinity DataIC50: 6.90E+3nMAssay Description:Concentration required to inhibit hydrolytic activity of bovine erythrocyte acetylcholinesterase by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TK2PubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)copy SMILEScopy InChI
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibitory binding activity against dopamine receptor using [3H]spiperone as the radioligand in striatal tissue of calf brain.More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Bos taurus (bovine))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50368268(CHEMBL1202155)copy SMILEScopy InChI
Affinity DataIC50: 9.90E+3nMAssay Description:Concentration required to inhibit hydrolytic activity of bovine erythrocyte acetylcholinesterase by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TK2PubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50223901(CHEMBL544695)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory binding activity against dopamine receptor using [3H]ADTN as the radioligand in striatal tissue of calf brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XD13WDPubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50223957(CHEMBL544931)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory binding activity against dopamine receptor using [3H]ADTN as the radioligand in striatal tissue of calf brain.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XD13WDPubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50107876((5,6-Dimethoxy-indan-2-yl)-dipropyl-amine | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibitory binding activity against dopamine receptor using [3H]spiperone as the radioligand in striatal tissue of calf brain.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XD13WDPubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50368272(CHEMBL1202157)copy SMILEScopy InChI
Affinity DataIC50: 1.42E+4nMAssay Description:Concentration required to inhibit hydrolytic activity of bovine erythrocyte acetylcholinesterase by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TK2PubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50290378(2-Dipropylamino-indan-5,6-diol | CHEMBL277743)copy SMILEScopy InChI
Affinity DataIC50: 1.76E+4nMAssay Description:Inhibitory binding activity against dopamine receptor using [3H]spiperone as the radioligand in striatal tissue of calf brain.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XD13WDPubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50012004((2-Biphenyl-4-yl-2-oxo-ethyl)-[1,3]dioxan-2-ylmeth...)copy SMILEScopy InChI
Affinity DataIC50: 2.01E+4nMAssay Description:Concentration required to inhibit hydrolytic activity of bovine erythrocyte acetylcholinesterase by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TK2PubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50224035(79907 | Lergotrile)copy SMILEScopy InChI
Affinity DataIC50: 2.37E+4nMAssay Description:Inhibitory binding activity against dopamine receptor using [3H]spiperone as the radioligand in striatal tissue of calf brain.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XD13WDPubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50368270(CHEMBL1202154)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Concentration required to inhibit hydrolytic activity of bovine erythrocyte acetylcholinesterase by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TK2PubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50223959(CHEMBL538227)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibitory binding activity against dopamine receptor using [3H]spiperone as the radioligand in striatal tissue of calf brain.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XD13WDPubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50224033(CHEMBL540009)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibitory binding activity against dopamine receptor using [3H]ADTN as the radioligand in striatal tissue of calf brain.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XD13WDPubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50224034(CHEMBL538726)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory binding activity against dopamine receptor using [3H]spiperone as the radioligand in striatal tissue of calf brain.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XD13WDPubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50223957(CHEMBL544931)copy SMILEScopy InChI
Affinity DataIC50: 5.39E+4nMAssay Description:Inhibitory binding activity against dopamine receptor using [3H]spiperone as the radioligand in striatal tissue of calf brain.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XD13WDPubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50223901(CHEMBL544695)copy SMILEScopy InChI
Affinity DataIC50: 9.10E+4nMAssay Description:Inhibitory binding activity against dopamine receptor using [3H]spiperone as the radioligand in striatal tissue of calf brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XD13WDPubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50011996(CHEMBL290329 | [1,3]Dioxan-2-ylmethyl-trimethyl-am...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration required to inhibit hydrolytic activity of bovine erythrocyte acetylcholinesterase by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TK2PubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50223900(CHEMBL34176)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory binding activity against dopamine receptor using [3H]spiperone as the radioligand in striatal tissue of calf brain.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XD13WDPubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50011998(CHEMBL298102 | [1,3]Dioxan-2-ylmethyl-dimethyl-(2-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration required to inhibit hydrolytic activity of bovine erythrocyte acetylcholinesterase by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TK2PubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50223956(CHEMBL555412)copy SMILEScopy InChI
Affinity DataIC50: 1.04E+5nMAssay Description:Inhibitory binding activity against dopamine receptor using [3H]spiperone as the radioligand in striatal tissue of calf brain.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XD13WDPubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50223958(CHEMBL544697)copy SMILEScopy InChI
Affinity DataIC50: 1.05E+5nMAssay Description:Inhibitory binding activity against dopamine receptor using [3H]spiperone as the radioligand in striatal tissue of calf brain.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XD13WDPubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibitory binding activity against dopamine receptor using [3H]spiperone as the radioligand in striatal tissue of calf brain.More data for this Ligand-Target Pair
TargetD(1A)/D(2) dopamine receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50224033(CHEMBL540009)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+5nMAssay Description:Inhibitory binding activity against dopamine receptor using [3H]spiperone as the radioligand in striatal tissue of calf brain.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XD13WDPubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50224036(CHEMBL543991)copy SMILEScopy InChI
Affinity DataIC50: 2.46E+5nMAssay Description:Inhibitory binding activity against dopamine receptor using [3H]spiperone as the radioligand in striatal tissue of calf brain.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XD13WDPubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50224034(CHEMBL538726)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibitory binding activity against dopamine receptor using [3H]ADTN as the radioligand in striatal tissue of calf brain.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XD13WDPubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50290378(2-Dipropylamino-indan-5,6-diol | CHEMBL277743)copy SMILEScopy InChI
Affinity DataIC50: 4.12E+5nMAssay Description:Inhibitory binding activity against dopamine receptor using [3H]ADTN as the radioligand in striatal tissue of calf brain.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XD13WDPubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50223959(CHEMBL538227)copy SMILEScopy InChI
Affinity DataIC50: 1.66E+6nMAssay Description:Inhibitory binding activity against dopamine receptor using [3H]ADTN as the radioligand in striatal tissue of calf brain.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XD13WDPubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50223900(CHEMBL34176)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+6nMAssay Description:Inhibitory binding activity against dopamine receptor using [3H]ADTN as the radioligand in striatal tissue of calf brain.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XD13WDPubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50223958(CHEMBL544697)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+7nMAssay Description:Inhibitory binding activity against dopamine receptor using [3H]ADTN as the radioligand in striatal tissue of calf brain.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XD13WDPubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM50107876((5,6-Dimethoxy-indan-2-yl)-dipropyl-amine | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 1.47E+8nMAssay Description:Inhibitory binding activity against dopamine receptor using [3H]ADTN as the radioligand in striatal tissue of calf brain.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XD13WDPubMed