Compile Data Set for Download or QSAR
Found 234 with Last Name = 'swales' and Initial = 'jg'
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50448693(CHEMBL3127857)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32149PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50448706(CHEMBL3127854)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32149PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50448731(CHEMBL3127868)copy SMILEScopy InChI
Affinity DataIC50: 0.430nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32149PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50448704(CHEMBL3127856)copy SMILEScopy InChI
Affinity DataIC50: 0.450nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32149PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50448705(CHEMBL3127855)copy SMILEScopy InChI
Affinity DataIC50: 0.490nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32149PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50448734(CHEMBL3127865)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32149PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50448733(CHEMBL3127866)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32149PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50448701(CHEMBL3127861)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32149PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50448697(CHEMBL3127858)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32149PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50448702(CHEMBL3127860)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32149PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50392216(CHEMBL2153191 | US8673938, 7)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of 11betaHSD1 in human isolated adipocytes using [3H]cortisone as substrate after 6 hrs by flow scintillation analysisMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50399335(CHEMBL2177609)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of 11betaHSD1 in human adipocytes assessed as cortisone to cortisol conversion by scintillation counting methodMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50394015(CHEMBL2158468)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human 11betaHSD1 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0V0GPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50392216(CHEMBL2153191 | US8673938, 7)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of 11betaHSD1 in human adipocytes assessed as cortisone to cortisol conversion by scintillation counting methodMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50448699(CHEMBL3127863)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32149PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50399353(CHEMBL2177615)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal 6-His tagged full length human 11betaHSD1 incubated for 25 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1FJTPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50394013(CHEMBL2158466)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human 11betaHSD1 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0V0GPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50448715(CHEMBL3127874)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32149PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50394016(CHEMBL2158469)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human 11betaHSD1 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0V0GPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50394014(CHEMBL2158467)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human 11betaHSD1 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0V0GPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50399348(CHEMBL2177620)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of N-terminal 6-His tagged full length human 11betaHSD1 incubated for 25 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1FJTPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50394017(CHEMBL2158470)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human 11betaHSD1 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0V0GPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50448703(CHEMBL3127859)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32149PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50448692(CHEMBL3127884)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32149PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50448732(CHEMBL3127867)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Inhibition of N-terminal 6-His-tagged full-length mouse 11beta-HSD1 assessed as conversion of cortisone to cortisol after 25 mins by competitive HTRF...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32149PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50399346(CHEMBL2180883)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of N-terminal 6-His tagged full length human 11betaHSD1 incubated for 25 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1FJTPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50399351(CHEMBL2177617)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of N-terminal 6-His tagged full length human 11betaHSD1 incubated for 25 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1FJTPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50448731(CHEMBL3127868)copy SMILEScopy InChI
Affinity DataIC50: 5.40nMAssay Description:Inhibition of N-terminal 6-His-tagged full-length mouse 11beta-HSD1 assessed as conversion of cortisone to cortisol after 25 mins by competitive HTRF...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32149PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50399336(CHEMBL2177608)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of N-terminal 6-His tagged full length human 11betaHSD1 incubated for 25 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1FJTPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50394000(CHEMBL2158481)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of mouse 11betaHSD1 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0V0GPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50399352(CHEMBL2177616)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of N-terminal 6-His tagged full length human 11betaHSD1 incubated for 25 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1FJTPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50448732(CHEMBL3127867)copy SMILEScopy InChI
Affinity DataIC50: 6.90nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32149PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50392216(CHEMBL2153191 | US8673938, 7)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of N-terminal 6-His tagged full length human 11betaHSD1 incubated for 25 mins by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50392222(CHEMBL2153178)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of N-terminal His6-tagged full length human 11betaHSD1 expressed in baculovirus infected cells using cortisone as substrate after 25 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1RTKPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50394011(CHEMBL2158464)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human 11betaHSD1 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0V0GPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50392216(CHEMBL2153191 | US8673938, 7)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of N-terminal His6-tagged full length human 11betaHSD1 expressed in baculovirus infected cells using cortisone as substrate after 25 mins ...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50448693(CHEMBL3127857)copy SMILEScopy InChI
Affinity DataIC50: 7.20nMAssay Description:Inhibition of N-terminal 6-His-tagged full-length human 11beta-HSD1 assessed as conversion of cortisone to cortisol after 25 mins by competitive HTRF...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32149PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50448706(CHEMBL3127854)copy SMILEScopy InChI
Affinity DataIC50: 7.20nMAssay Description:Inhibition of N-terminal 6-His-tagged full-length human 11beta-HSD1 assessed as conversion of cortisone to cortisol after 25 mins by competitive HTRF...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32149PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50448696(CHEMBL3127869)copy SMILEScopy InChI
Affinity DataIC50: 8.10nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32149PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50448723(CHEMBL3127891)copy SMILEScopy InChI
Affinity DataIC50: 8.30nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32149PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50448734(CHEMBL3127865)copy SMILEScopy InChI
Affinity DataIC50: 8.80nMAssay Description:Inhibition of N-terminal 6-His-tagged full-length mouse 11beta-HSD1 assessed as conversion of cortisone to cortisol after 25 mins by competitive HTRF...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32149PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50448704(CHEMBL3127856)copy SMILEScopy InChI
Affinity DataIC50: 8.90nMAssay Description:Inhibition of N-terminal 6-His-tagged full-length mouse 11beta-HSD1 assessed as conversion of cortisone to cortisol after 25 mins by competitive HTRF...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32149PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50399335(CHEMBL2177609)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of N-terminal 6-His tagged full length human 11betaHSD1 incubated for 25 mins by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50394010(CHEMBL2158007)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human 11betaHSD1 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0V0GPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50448698(CHEMBL3127864)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32149PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50399338(CHEMBL2177606)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of N-terminal 6-His tagged full length human 11betaHSD1 incubated for 25 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1FJTPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50448702(CHEMBL3127860)copy SMILEScopy InChI
Affinity DataIC50: 9.10nMAssay Description:Inhibition of N-terminal 6-His-tagged full-length human 11beta-HSD1 assessed as conversion of cortisone to cortisol after 25 mins by competitive HTRF...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32149PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50448731(CHEMBL3127868)copy SMILEScopy InChI
Affinity DataIC50: 9.10nMAssay Description:Inhibition of N-terminal 6-His-tagged full-length human 11beta-HSD1 assessed as conversion of cortisone to cortisol after 25 mins by competitive HTRF...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32149PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50448705(CHEMBL3127855)copy SMILEScopy InChI
Affinity DataIC50: 9.90nMAssay Description:Inhibition of N-terminal 6-His-tagged full-length mouse 11beta-HSD1 assessed as conversion of cortisone to cortisol after 25 mins by competitive HTRF...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32149PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50448700(CHEMBL3127862)copy SMILEScopy InChI
Affinity DataIC50: 9.90nMAssay Description:Inhibition of N-terminal 6-His-tagged full-length human 11beta-HSD1 assessed as conversion of cortisone to cortisol after 25 mins by competitive HTRF...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32149PubMed
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