Compile Data Set for Download or QSAR
Found 81 with Last Name = 'heym' and Initial = 'jh'
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Torpedo californica)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50143282((-)-cytisine | (1R,5S)-1,2,3,4,5,6-Hexahydro-1,5-m...)copy SMILEScopy InChI
Affinity DataKi:  250nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to nicotinic acetylcholine receptor alpha1 beta gamma delta of electroplaxMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87BJ7PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50166908(5,8,14-triazatetracyclo[10.3.1.02,11.04,9]hexadeca...)copy SMILEScopy InChI
Affinity DataKi:  322nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to nicotinic acetylcholine receptor alpha-7 subunit in rat GH4C1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87BJ7PubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Torpedo californica)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50166909(10-Aza-tricyclo[6.3.1.0*2,7*]dodeca-2(7),3,5-trien...)copy SMILEScopy InChI
Affinity DataKi:  370nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to nicotinic acetylcholine receptor alpha1 beta gamma delta of electroplaxMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87BJ7PubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Torpedo californica)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50166907(4-nitro-10-azatricyclo[6.3.1.02,7]dodeca-2(7),3,5-...)copy SMILEScopy InChI
Affinity DataKi:  690nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to nicotinic acetylcholine receptor alpha1 beta gamma delta of electroplaxMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87BJ7PubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Torpedo californica)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50166908(5,8,14-triazatetracyclo[10.3.1.02,11.04,9]hexadeca...)copy SMILEScopy InChI
Affinity DataKi:  3.54E+3nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to nicotinic acetylcholine receptor alpha1 beta gamma delta of electroplaxMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87BJ7PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50143282((-)-cytisine | (1R,5S)-1,2,3,4,5,6-Hexahydro-1,5-m...)copy SMILEScopy InChI
Affinity DataKi:  4.20E+3nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to nicotinic acetylcholine receptor alpha-7 subunit in rat GH4C1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87BJ7PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50166909(10-Aza-tricyclo[6.3.1.0*2,7*]dodeca-2(7),3,5-trien...)copy SMILEScopy InChI
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to nicotinic acetylcholine receptor alpha-7 subunit in rat GH4C1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87BJ7PubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Torpedo californica)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)copy SMILEScopy InChI
Affinity DataKi:  6.27E+3nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to nicotinic acetylcholine receptor alpha1 beta gamma delta of electroplaxMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)copy SMILEScopy InChI
Affinity DataKi:  6.29E+3nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to nicotinic acetylcholine receptor alpha-7 subunit in rat GH4C1 cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50166907(4-nitro-10-azatricyclo[6.3.1.02,7]dodeca-2(7),3,5-...)copy SMILEScopy InChI
Affinity DataKi:  7.34E+3nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to nicotinic acetylcholine receptor alpha-7 subunit in rat GH4C1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87BJ7PubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50015711(3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1H-indole-5-ca...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50015714(3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1H-indol-5-ol ...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50015712(5-Fluoro-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-in...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM81498(5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-i...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM50007558(6-[2-(4-Naphthalen-1-yl-piperazin-1-yl)-ethyl]-3H-...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in the rat brain using [3H]-8-hydroxy-2-(di-n-propylamine)tetralin as radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NK3PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM50007563(1-Ethyl-5-[2-(4-naphthalen-1-yl-piperazin-1-yl)-et...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in the rat brain using [3H]-8-hydroxy-2-(di-n-propylamine)tetralin as radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NK3PubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1D receptor of bovine caudate using [3H]-5-HT as the radioligandMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Compound was evaluated In vitro for its activity by binding to Dopamine receptor D2 in the rat brain using [3H]-NPA as radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NK3PubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50015709(5-Bromo-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-ind...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50015717(5-Chloro-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-in...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50015718(5-Nitro-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-ind...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM31023(3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HT as the radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM50007559(5-[2-(4-Naphthalen-1-yl-piperazin-1-yl)-ethyl]-1,3...)copy SMILEScopy InChI
Affinity DataIC50: 4.87nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in the rat brain using [3H]-8-hydroxy-2-(di-n-propylamine)tetralin as radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NK3PubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HT as the radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM50007556(6-[2-(4-Naphthalen-1-yl-piperazin-1-yl)-ethyl]-3H-...)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in the rat brain using [3H]-8-hydroxy-2-(di-n-propylamine)tetralin as radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NK3PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM50007557(3,3-Dimethyl-5-[2-(4-naphthalen-1-yl-piperazin-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 6.90nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in the rat brain using [3H]-8-hydroxy-2-(di-n-propylamine)tetralin as radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NK3PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM50007562(4-{4-[2-(4-Naphthalen-1-yl-piperazin-1-yl)-ethyl]-...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor in the rat brain using [3H]-8-hydroxy-2-(di-n-propylamine)tetralin as radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NK3PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM50015709(5-Bromo-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-ind...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM81498(5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-i...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM84737(3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1,4-dihydro-py...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]5-HTMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM81497(4-(4-Methyl-piperazin-1-yl)-7-trifluoromethyl-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50015710(4-Piperazin-1-yl-7-trifluoromethyl-pyrrolo[1,2-a]q...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM50015717(5-Chloro-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-in...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50007406(1-(3-(trifluoromethyl)phenyl)piperazine | 1-(3-Tri...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM50015714(3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1H-indol-5-ol ...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM50015711(3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1H-indole-5-ca...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM81497(4-(4-Methyl-piperazin-1-yl)-7-trifluoromethyl-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Compound was evaluated for its inhibitory activity against 5-hydroxytryptamine 1D receptor of bovine caudate using [3H]-5-HT as the radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM50015718(5-Nitro-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-ind...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM50015710(4-Piperazin-1-yl-7-trifluoromethyl-pyrrolo[1,2-a]q...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM50007559(5-[2-(4-Naphthalen-1-yl-piperazin-1-yl)-ethyl]-1,3...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Binding affinity to dopamine receptor D2 in the rat brain using [3H]-NPA as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NK3PubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM81498(5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-i...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Compound was evaluated for its inhibitory activity against 5-hydroxytryptamine 1D receptor of bovine caudate using [3H]-5-HT as the radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM50007556(6-[2-(4-Naphthalen-1-yl-piperazin-1-yl)-ethyl]-3H-...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Binding affinity to dopamine receptor D2 in the rat brain using [3H]-NPA as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NK3PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM50015712(5-Fluoro-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-in...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM50007562(4-{4-[2-(4-Naphthalen-1-yl-piperazin-1-yl)-ethyl]-...)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Binding affinity to dopamine receptor D2 in the rat brain using [3H]-NPA as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NK3PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM50007565(4-{4-[2-(4-Naphthalen-1-yl-piperazin-1-yl)-ethyl]-...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Binding affinity to dopamine receptor D2 in the rat brain using [3H]-NPA as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NK3PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)copy SMILEScopy InChI
Affinity DataIC50: 81nMAssay Description:inhibitory activity against 5-hydroxytryptamine 1C receptor of pig choroid plexus using [3H]-mesulergine as the radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GQ6WR3PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM50007563(1-Ethyl-5-[2-(4-naphthalen-1-yl-piperazin-1-yl)-et...)copy SMILEScopy InChI
Affinity DataIC50: 81.2nMAssay Description:Binding affinity to dopamine receptor D2 in the rat brain using [3H]-NPA as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NK3PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM50007560(1-Naphthalen-1-yl-4-[2-(4-[1,2,3]thiadiazol-4-yl-p...)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Binding affinity to dopamine receptor D2 in the rat brain using [3H]-NPA as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NK3PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM50007557(3,3-Dimethyl-5-[2-(4-naphthalen-1-yl-piperazin-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Binding affinity to dopamine receptor D2 in the rat brain using [3H]-NPA as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NK3PubMed
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