Compile Data Set for Download or QSAR
Found 223 with Last Name = 'zhang' and Initial = 'jh'
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324297(4-(1-Piperazin-1-yl[2,6]naphthyridin-3-yl)pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324315(CHEMBL1214998 | Cyclohexyl-[4-(1-piperazin-1-yl[2,...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324298(CHEMBL1215712 | {4-[1-(4-Isobutylpiperazin-1-yl)[2...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
LigandPNGBDBM50531540(CHEBI:75998 | GSK-1120212 | GSK1120212 | JTP 74057...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of MEK in human KYSE-520 cells assessed as reduction in p-ERK levelsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324296(1-[3-(2-Cyclohexylaminopyridin-4-yl)[2,6]naphthyri...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetSerine/threonine-protein kinase WNK1 [166-489](Homo sapiens (Human))
Novartis Institutes

LigandPNGBDBM203827(N-(tert-butyl)-1-(1-(5-(5-(trifluoromethyl)-1,3,4-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.3 T: 2°CAssay Description:Each well of the MBP-coated ScintiPlates held 100 ul of a solution containing 20 mM HEPES pH 7.3, 5 mM MnCl2 (WNK1 and WNK4) or 3 mM MnCl2 (WNK2 and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5FH5PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324314(1-{3-[2-(Tetrahydropyran-4-ylamino)pyridin-4-yl][2...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324306(1-[3-(2-Cyclohexylaminopyridin-4-yl)[2,6]naphthyri...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324305(CHEMBL1214711 | N-(2-(pyrrolidin-1-yl)ethyl)-1-(3-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324292(CHEMBL1215641 | Cyclohexyl-{4-[1-(4-methylpiperazi...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324294(CHEMBL1215643 | Cyclohexyl-{4-[1-(4-cyclopropylmet...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324313(1-{3-[2-(Tetrahydropyran-4-ylamino)pyridin-4-yl][2...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324312(1-{3-[2-(Tetrahydropyran-4-ylamino)pyridin-4-yl][2...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324309(1-{3-[2-(Tetrahydropyran-4-ylamino)pyridin-4-yl][2...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324311(1-{3-[2-(Tetrahydropyran-4-ylamino)pyridin-4-yl][2...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324310(1-{3-[2-(Tetrahydropyran-4-ylamino)pyridin-4-yl][2...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324291(CHEMBL1215640 | Cyclohexyl-{4-[1-((cis-3,5-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324304(1-[3-(2-Cyclohexylaminopyridin-4-yl)[2,6]naphthyri...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50337697((R)-N-(1-cyanoethyl)-3-(5-(4-((isopropylamino)meth...)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM29WXPubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM3033(3-{23-methyl-14-oxo-3,13,23-triazahexacyclo[14.7.0...)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Inhibition of PKCalpha by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324307(CHEMBL1214786 | {1-[3-(2-Cyclohexylaminopyridin-4-...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetSerine/threonine-protein kinase WNK1 [1-491](Homo sapiens (Human))
Novartis Institutes

LigandPNGBDBM203827(N-(tert-butyl)-1-(1-(5-(5-(trifluoromethyl)-1,3,4-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.3 T: 2°CAssay Description:Each well of the MBP-coated ScintiPlates held 100 ul of a solution containing 20 mM HEPES pH 7.3, 5 mM MnCl2 (WNK1 and WNK4) or 3 mM MnCl2 (WNK2 and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5FH5PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324308(2-Amino-1-(4-{3-[2-(tetrahydropyran-4-ylamino)pyri...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50337694((R)-N-(1-cyanoethyl)-3-(5-(4-((tetrahydro-2H-pyran...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM29WXPubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324293(CHEMBL1215642 | Cyclohexyl-{4-[1-(4-isobutylpipera...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetSerine/threonine-protein kinase WNK1 [1-434](Homo sapiens (Human))
Novartis Institutes

LigandPNGBDBM203827(N-(tert-butyl)-1-(1-(5-(5-(trifluoromethyl)-1,3,4-...)copy SMILEScopy InChI
Affinity DataIC50: 6nMpH: 7.3 T: 2°CAssay Description:Each well of the MBP-coated ScintiPlates held 100 ul of a solution containing 20 mM HEPES pH 7.3, 5 mM MnCl2 (WNK1 and WNK4) or 3 mM MnCl2 (WNK2 and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5FH5PubMed
LigandPNGBDBM408067(US10336774, Example 52)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Allosteric inhibition of 6x-histidine tagged human SHP2 (Met1-L525 residues) expressed in Escherichia coli BL21 Star (DE3) using IRS1_pY1172(dPEG8)pY...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC14BBPubMed
TargetSerine/threonine-protein kinase WNK1 [1-444](Homo sapiens (Human))
Novartis Institutes

LigandPNGBDBM203827(N-(tert-butyl)-1-(1-(5-(5-(trifluoromethyl)-1,3,4-...)copy SMILEScopy InChI
Affinity DataIC50: 9nMpH: 7.3 T: 2°CAssay Description:Each well of the MBP-coated ScintiPlates held 100 ul of a solution containing 20 mM HEPES pH 7.3, 5 mM MnCl2 (WNK1 and WNK4) or 3 mM MnCl2 (WNK2 and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5FH5PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50337698((R)-N-(1-cyanoethyl)-3-(5-(4-((isopropylamino)meth...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM29WXPubMed
LigandPNGBDBM50553790(CHEMBL4763213)copy SMILES
Affinity DataIC50: 10nMAssay Description:Allosteric inhibition of 6x-histidine tagged human SHP2 (Met1-L525 residues) expressed in Escherichia coli BL21 Star (DE3) using IRS1_pY1172(dPEG8)pY...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC14BBPubMed
TargetGTPase KRas(Homo sapiens (Human))TBA
LigandPNGBDBM50539763(Adagrasib | Mrtx-849 | Mrtx849)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of KRAS G12C mutant in human MIA PaCa-2 cells assessed as reduction in p-ERK levelsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC14BBPubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324297(4-(1-Piperazin-1-yl[2,6]naphthyridin-3-yl)pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of PKD1 assessed as HDAC5 neuclear exportMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
LigandPNGBDBM50553783(Ptpn11 inhibitor tno155 | Shp2 inhibitor tno155 | ...)copy SMILES
Affinity DataIC50: 11nMAssay Description:Allosteric inhibition of human SHP2 in human KYSE-520 cells assessed as reduction in ERK1/2 phosphorylation by fluorescence based assayMore data for this Ligand-Target Pair
LigandPNGBDBM50553783(Ptpn11 inhibitor tno155 | Shp2 inhibitor tno155 | ...)copy SMILES
Affinity DataIC50: 11nMAssay Description:Allosteric inhibition of 6x-histidine tagged human SHP2 (Met1-L525 residues) expressed in Escherichia coli BL21 Star (DE3) using IRS1_pY1172(dPEG8)pY...More data for this Ligand-Target Pair
LigandPNGBDBM50553787(CHEMBL4755819)copy SMILES
Affinity DataIC50: 12nMAssay Description:Allosteric inhibition of 6x-histidine tagged human SHP2 (Met1-L525 residues) expressed in Escherichia coli BL21 Star (DE3) using IRS1_pY1172(dPEG8)pY...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC14BBPubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324286(1-(1-Piperazinyl)-3-(2-cyclohexylaminopyrid-4-yl)i...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
LigandPNGBDBM50553790(CHEMBL4763213)copy SMILES
Affinity DataIC50: 13nMAssay Description:Allosteric inhibition of human SHP2 in human KYSE-520 cells assessed as reduction in ERK1/2 phosphorylation by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC14BBPubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324295(CHEMBL1215709 | Cyclohexyl-{4-[1-(4-cyclopropylpip...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
LigandPNGBDBM50553789(CHEMBL4747789)copy SMILES
Affinity DataIC50: 14nMAssay Description:Allosteric inhibition of 6x-histidine tagged human SHP2 (Met1-L525 residues) expressed in Escherichia coli BL21 Star (DE3) using IRS1_pY1172(dPEG8)pY...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC14BBPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of EGFR in human KYSE-520 cells assessed as reduction in p-ERK levelsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324289(CHEMBL1215572 | Cyclohexyl-[4-(5-piperazin-1-yl[1,...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324300(1-[3-(2-Cyclohexylaminopyridin-4-yl)[2,6]naphthyri...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
LigandPNGBDBM50553791(CHEMBL4743002)copy SMILES
Affinity DataIC50: 17nMAssay Description:Allosteric inhibition of 6x-histidine tagged human SHP2 (Met1-L525 residues) expressed in Escherichia coli BL21 Star (DE3) using IRS1_pY1172(dPEG8)pY...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC14BBPubMed
TargetSerine/threonine-protein kinase D3(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50337694((R)-N-(1-cyanoethyl)-3-(5-(4-((tetrahydro-2H-pyran...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of human PKD3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM29WXPubMed
LigandPNGBDBM50553786(CHEMBL4789106)copy SMILES
Affinity DataIC50: 17nMAssay Description:Allosteric inhibition of 6x-histidine tagged human SHP2 (Met1-L525 residues) expressed in Escherichia coli BL21 Star (DE3) using IRS1_pY1172(dPEG8)pY...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324302(1-{4-[3-(2-Cyclohexylaminopyridin-4-yl)[2,6]naphth...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50337718(CHEMBL1683438 | N-(cyanomethyl)-3-(5-(4-((tetrahyd...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM29WXPubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324316(CHEMBL1214929 | N*1*-(3-Pyridin-4-yl[2,6]naphthyri...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of PKCdelta by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50324309(1-{3-[2-(Tetrahydropyran-4-ylamino)pyridin-4-yl][2...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of PKD1 assessed as HDAC5 neuclear exportMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T153T9PubMed
LigandPNGBDBM392338(US10301278, Example 20)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Allosteric inhibition of 6x-histidine tagged human SHP2 (Met1-L525 residues) expressed in Escherichia coli BL21 Star (DE3) using IRS1_pY1172(dPEG8)pY...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC14BBPubMed
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