Compile Data Set for Download or QSAR
Found 263 with Last Name = 'kovacs' and Initial = 'jj'
LigandPNGBDBM50560806(CHEMBL4758092)copy SMILES
Affinity DataIC50: 0.800nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50560807(CHEMBL4751287)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50560804(CHEMBL4763875)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50460035(CHEMBL4227505)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of CSF1R (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50560786(CHEMBL4798876)copy SMILES
Affinity DataIC50: 1.10nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50560798(CHEMBL4795462)copy SMILES
Affinity DataIC50: 1.10nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50560791(CHEMBL4740157)copy SMILES
Affinity DataIC50: 1.20nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50560801(CHEMBL4798601)copy SMILES
Affinity DataIC50: 1.20nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50560788(CHEMBL4759047)copy SMILES
Affinity DataIC50: 1.40nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50560812(CHEMBL4748740)copy SMILES
Affinity DataIC50: 1.70nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50560790(CHEMBL4741283)copy SMILES
Affinity DataIC50: 2nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50560789(CHEMBL4779878)copy SMILES
Affinity DataIC50: 2nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50560816(CHEMBL4756510)copy SMILES
Affinity DataIC50: 2.40nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50560800(CHEMBL4779197)copy SMILES
Affinity DataIC50: 2.60nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50560793(CHEMBL4788945)copy SMILES
Affinity DataIC50: 4nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50560813(CHEMBL4746711)copy SMILES
Affinity DataIC50: 4nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50560785(CHEMBL4754431)copy SMILES
Affinity DataIC50: 4nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50560797(CHEMBL4763289)copy SMILES
Affinity DataIC50: 5.70nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM404825(1-(4-{6-[2-(pyridin-2- yl)acetamido]pyridazin-3-yl...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8WGCPubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM109086(US10793535, Cmpd ID 727 | US8604016, 670 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
LigandPNGBDBM50560792(CHEMBL4762843)copy SMILES
Affinity DataIC50: 7nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50560812(CHEMBL4748740)copy SMILES
Affinity DataIC50: 7nMAssay Description:Inhibition of CSF1R in mouse NFS-60 cells assessed as reduction in CSF-induced cell proliferation after 72 hrs by CellTiter-Glo assayMore data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50560806(CHEMBL4758092)copy SMILES
Affinity DataIC50: 7nMAssay Description:Inhibition of CSF1R in mouse NFS-60 cells assessed as reduction in CSF-induced cell proliferation after 72 hrs by CellTiter-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50560809(CHEMBL4787609)copy SMILES
Affinity DataIC50: 9nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM404848(N-methyl-1-{4-[6-(2-{4-[3- (trifluoromethoxy)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8WGCPubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM404911((R)-1-(2-fluoro-4-(6-(2-(4-(3- (trifluoromethoxy)p...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8WGCPubMed
LigandPNGBDBM384117(1-(3-(2,3-dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazi...)copy SMILEScopy InChI
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
LigandPNGBDBM50560815(CHEMBL4790139)copy SMILES
Affinity DataIC50: 11nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM384152((S)-8-(3-(2,3-Dichlorophenyl)-1H-pyrazolo[3,4-b]py...)copy SMILES
Affinity DataIC50: 12nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9VC6PubMed
LigandPNGBDBM50560791(CHEMBL4740157)copy SMILES
Affinity DataIC50: 14nMAssay Description:Inhibition of CSF1R in mouse NFS-60 cells assessed as reduction in CSF-induced cell proliferation after 72 hrs by CellTiter-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM404666(US10344025, Example 5 | US11370786, Example 5)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8WGCPubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM405185(N-(pyridin-2-ylmethyl)-1-[4-(6-{2-[3- (trifluorome...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8WGCPubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM405183(N-(cyanomethyl)-1-[4-(6-{2-[3- (trifluoromethoxy)p...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8WGCPubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM50548670(CHEMBL4741924)copy SMILES
Affinity DataIC50: 16nMAssay Description:Inhibition of GLS1 in human A549 cells assessed as reduction in conversion of glutamine to glutamate measured after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8WGCPubMed
LigandPNGBDBM50560810(CHEMBL4798920)copy SMILES
Affinity DataIC50: 17nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50560812(CHEMBL4748740)copy SMILES
Affinity DataIC50: 17nMAssay Description:Inhibition of CSF1R phosphorylation in M-CSF induced human THP1 cells incubated for 30 mins by ELISA assayMore data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM404924((R)-1-(2-fluoro-4-(6-(2-(6-methyl-4- (trifluoromet...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8WGCPubMed
LigandPNGBDBM50560795(CHEMBL4788832)copy SMILES
Affinity DataIC50: 21nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM50548671(CHEMBL4797071)copy SMILES
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8WGCPubMed
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