TargetD(2) dopamine receptor(Homo sapiens (Human))
National Center for Advancing Translational Sciences
Curated by ChEMBL
National Center for Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Center for Advancing Translational Sciences
Curated by ChEMBL
National Center for Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Center for Advancing Translational Sciences
Curated by ChEMBL
National Center for Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor expressed in HEK293 cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Center for Advancing Translational Sciences
Curated by ChEMBL
National Center for Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 7.5nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Binding affinity to human SST4 receptorMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Binding affinity to human SST4 receptorMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Center for Advancing Translational Sciences
Curated by ChEMBL
National Center for Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 23nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataKi: 26nMAssay Description:Binding affinity to human SST4 receptorMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Center for Advancing Translational Sciences
Curated by ChEMBL
National Center for Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 49nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor expressed in HEK293 cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Center for Advancing Translational Sciences
Curated by ChEMBL
National Center for Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 88nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor expressed in HEK293 cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Center for Advancing Translational Sciences
Curated by ChEMBL
National Center for Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 90nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Center for Advancing Translational Sciences
Curated by ChEMBL
National Center for Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Center for Advancing Translational Sciences
Curated by ChEMBL
National Center for Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 130nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor expressed in HEK293 cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Center for Advancing Translational Sciences
Curated by ChEMBL
National Center for Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 158nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataKi: 160nMAssay Description:Binding affinity to human SST4 receptorMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Center for Advancing Translational Sciences
Curated by ChEMBL
National Center for Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 190nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Center for Advancing Translational Sciences
Curated by ChEMBL
National Center for Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 210nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Center for Advancing Translational Sciences
Curated by ChEMBL
National Center for Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 230nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor expressed in HEK293 cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Center for Advancing Translational Sciences
Curated by ChEMBL
National Center for Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 240nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Center for Advancing Translational Sciences
Curated by ChEMBL
National Center for Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 290nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Center for Advancing Translational Sciences
Curated by ChEMBL
National Center for Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Center for Advancing Translational Sciences
Curated by ChEMBL
National Center for Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 310nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Center for Advancing Translational Sciences
Curated by ChEMBL
National Center for Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 350nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor expressed in HEK293 cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Center for Advancing Translational Sciences
Curated by ChEMBL
National Center for Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 370nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor expressed in HEK293 cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health , 10 Center Drive, Bethesda, Maryland 20892-1800, United States.
Curated by ChEMBL
Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health , 10 Center Drive, Bethesda, Maryland 20892-1800, United States.
Curated by ChEMBL
Affinity DataKi: 415nMAssay Description:Displacement of [3H]LSD from human 5-HT2B receptor expressed in HEK cell membranes after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health , 10 Center Drive, Bethesda, Maryland 20892-1800, United States.
Curated by ChEMBL
Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health , 10 Center Drive, Bethesda, Maryland 20892-1800, United States.
Curated by ChEMBL
Affinity DataKi: 443nMAssay Description:Displacement of [3H]Cimetidine from human H2 receptor expressed in HEK cell membranes after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Center for Advancing Translational Sciences
Curated by ChEMBL
National Center for Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 530nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health , 10 Center Drive, Bethesda, Maryland 20892-1800, United States.
Curated by ChEMBL
Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health , 10 Center Drive, Bethesda, Maryland 20892-1800, United States.
Curated by ChEMBL
Affinity DataKi: 575nMAssay Description:Displacement of [3H]Rauwolscine from human alpha2C receptor expressed in MDCK cell membranes after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National Human Genome Research Institute
Curated by ChEMBL
National Human Genome Research Institute
Curated by ChEMBL
Affinity DataKi: 690nMAssay Description:Binding affinity to human SST4 receptorMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Center for Advancing Translational Sciences
Curated by ChEMBL
National Center for Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 880nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor expressed in HEK293 cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Center for Advancing Translational Sciences
Curated by ChEMBL
National Center for Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 1.16E+3nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor expressed in HEK293 cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health , 10 Center Drive, Bethesda, Maryland 20892-1800, United States.
Curated by ChEMBL
Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health , 10 Center Drive, Bethesda, Maryland 20892-1800, United States.
Curated by ChEMBL
Affinity DataKi: 1.21E+3nMAssay Description:Displacement of [3H]U69593 from KOR receptor (unknown origin) expressed in HEK cell membranes after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health , 10 Center Drive, Bethesda, Maryland 20892-1800, United States.
Curated by ChEMBL
Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health , 10 Center Drive, Bethesda, Maryland 20892-1800, United States.
Curated by ChEMBL
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health , 10 Center Drive, Bethesda, Maryland 20892-1800, United States.
Curated by ChEMBL
Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health , 10 Center Drive, Bethesda, Maryland 20892-1800, United States.
Curated by ChEMBL
Affinity DataKi: 1.29E+3nMAssay Description:Displacement of [3H]Nisoxetine from human NET receptor expressed in HEK cell membranes after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health , 10 Center Drive, Bethesda, Maryland 20892-1800, United States.
Curated by ChEMBL
Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health , 10 Center Drive, Bethesda, Maryland 20892-1800, United States.
Curated by ChEMBL
Affinity DataKi: 1.42E+3nMAssay Description:Displacement of [3H]Rauwolscine from human alpha2A receptor expressed in MDCK cell membranes after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health , 10 Center Drive, Bethesda, Maryland 20892-1800, United States.
Curated by ChEMBL
Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health , 10 Center Drive, Bethesda, Maryland 20892-1800, United States.
Curated by ChEMBL
Affinity DataKi: 1.75E+3nMAssay Description:Displacement of [3H]QNB from human M5 receptor expressed in CHO cell membranes after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health , 10 Center Drive, Bethesda, Maryland 20892-1800, United States.
Curated by ChEMBL
Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health , 10 Center Drive, Bethesda, Maryland 20892-1800, United States.
Curated by ChEMBL
Affinity DataKi: 1.81E+3nMAssay Description:Displacement of [3H]Pentazocine from guinea pig Sigma1 receptor after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Center for Advancing Translational Sciences
Curated by ChEMBL
National Center for Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 1.90E+3nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor expressed in HEK293 cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health , 10 Center Drive, Bethesda, Maryland 20892-1800, United States.
Curated by ChEMBL
Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health , 10 Center Drive, Bethesda, Maryland 20892-1800, United States.
Curated by ChEMBL
Affinity DataKi: 2.50E+3nMAssay Description:Displacement of [3H]Citalopram from human SERT receptor expressed in HEK cell membranes after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Center for Advancing Translational Sciences
Curated by ChEMBL
National Center for Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 3.40E+3nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor expressed in HEK293 cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Center for Advancing Translational Sciences
Curated by ChEMBL
National Center for Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 4.10E+3nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor expressed in HEK293 cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Center for Advancing Translational Sciences
Curated by ChEMBL
National Center for Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 9.20E+3nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor expressed in HEK293 cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Center for Advancing Translational Sciences
Curated by ChEMBL
National Center for Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 2.10E+4nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor expressed in HEK293 cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Center for Advancing Translational Sciences
Curated by ChEMBL
National Center for Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Center for Advancing Translational Sciences
Curated by ChEMBL
National Center for Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor expressed in HEK293 cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Johnson& Johnson, Pharmaceutical Research and Development, L.L.C.
Curated by ChEMBL
Johnson& Johnson, Pharmaceutical Research and Development, L.L.C.
Curated by ChEMBL
Affinity DataIC50: 0.25nMAssay Description:Inhibitory concentration against alphaV-beta3 integrinMore data for this Ligand-Target Pair