Compile Data Set for Download or QSAR
Found 273 with Last Name = 'wilkes' and Initial = 'jj'
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267028(CHEMBL4073525)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CD5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267031(CHEMBL4079930)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CD5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267009(CHEMBL4089171)copy SMILEScopy InChI
Affinity DataKi:  35nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CD5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267029(CHEMBL4069191)copy SMILEScopy InChI
Affinity DataKi:  39nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CD5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267010(CHEMBL4082395)copy SMILEScopy InChI
Affinity DataKi:  45nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CD5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267117(CHEMBL4060499)copy SMILEScopy InChI
Affinity DataKi:  49nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CD5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267030(CHEMBL4090240)copy SMILEScopy InChI
Affinity DataKi:  60nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CD5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267044(CHEMBL4069764)copy SMILEScopy InChI
Affinity DataKi:  73nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CD5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267039(CHEMBL4090766)copy SMILEScopy InChI
Affinity DataKi:  180nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CD5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267035(CHEMBL4071899)copy SMILEScopy InChI
Affinity DataKi:  310nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CD5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267049(CHEMBL4095599)copy SMILEScopy InChI
Affinity DataKi:  310nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CD5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267038(CHEMBL4061093)copy SMILEScopy InChI
Affinity DataKi:  360nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CD5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267046(CHEMBL4103729)copy SMILEScopy InChI
Affinity DataKi:  890nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CD5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267066(CHEMBL4067052)copy SMILEScopy InChI
Affinity DataKi:  1.30E+3nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CD5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267118(CHEMBL4096887)copy SMILEScopy InChI
Affinity DataKi:  1.30E+3nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CD5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267059(CHEMBL4091552)copy SMILEScopy InChI
Affinity DataKi:  1.80E+3nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CD5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267047(CHEMBL4078852)copy SMILEScopy InChI
Affinity DataKi:  4.40E+3nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CD5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267064(CHEMBL4070703)copy SMILEScopy InChI
Affinity DataKi:  6.50E+3nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CD5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267045(CHEMBL4063889)copy SMILEScopy InChI
Affinity DataKi:  9.00E+3nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CD5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267048(CHEMBL4075190)copy SMILEScopy InChI
Affinity DataKi:  2.30E+4nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CD5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267021(CHEMBL4091669)copy SMILEScopy InChI
Affinity DataKi: >2.50E+4nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CD5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267113(CHEMBL4105565)copy SMILEScopy InChI
Affinity DataKi: >3.30E+4nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CD5PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50244066(CHEMBL4083365)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CD5PubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))TBA
LigandPNGBDBM50243975(CHEMBL4080226)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 2C8(Homo sapiens (Human))TBA
LigandPNGBDBM50244066(CHEMBL4083365)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CD5PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50243975(CHEMBL4080226)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 2C8(Homo sapiens (Human))TBA
LigandPNGBDBM50244066(CHEMBL4083365)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CD5PubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Bristol-Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50243975(CHEMBL4080226)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of MAO-B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6MTMPubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))TBA
LigandPNGBDBM50243975(CHEMBL4080226)copy SMILEScopy InChI
Affinity DataIC50: 8.10E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 2C8(Homo sapiens (Human))TBA
LigandPNGBDBM50614666(CHEMBL5285988)copy SMILES
Affinity DataIC50: 8.30E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCytochrome P450 2C9(Homo sapiens (Human))TBA
LigandPNGBDBM50243975(CHEMBL4080226)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMMore data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 2B6(Homo sapiens (Human))TBA
LigandPNGBDBM50614666(CHEMBL5285988)copy SMILES
Affinity DataIC50: 2.90E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCytochrome P450 2C9(Homo sapiens (Human))TBA
LigandPNGBDBM50614666(CHEMBL5285988)copy SMILES
Affinity DataIC50: 3.40E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCytochrome P450 2C19(Homo sapiens (Human))TBA
LigandPNGBDBM50243975(CHEMBL4080226)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+4nMMore data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 2D6(Homo sapiens (Human))TBA
LigandPNGBDBM50243975(CHEMBL4080226)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
TargetCytochrome P450 2C19(Homo sapiens (Human))TBA
LigandPNGBDBM50614666(CHEMBL5285988)copy SMILES
Affinity DataIC50: 4.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCytochrome P450 2D6(Homo sapiens (Human))TBA
LigandPNGBDBM50614666(CHEMBL5285988)copy SMILES
Affinity DataIC50: 4.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50614666(CHEMBL5285988)copy SMILES
Affinity DataIC50: 4.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Bristol-Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50243976(CHEMBL4105324)copy SMILEScopy InChI
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at PPARgamma (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6MTMPubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Bristol-Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50243983(CHEMBL4086198)copy SMILEScopy InChI
Affinity DataEC50:  2.60E+3nMAssay Description:Agonist activity at PPARgamma (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6MTMPubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50243984(CHEMBL4063905)copy SMILEScopy InChI
Affinity DataEC50:  600nMAssay Description:Agonist activity at human GPR40 expressed in CHOA12 cells assessed as induction of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6MTMPubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50243997(CHEMBL4092937)copy SMILEScopy InChI
Affinity DataEC50:  450nMAssay Description:Agonist activity at human GPR40 expressed in CHOA12 cells assessed as induction of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6MTMPubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50243998(CHEMBL4082133)copy SMILEScopy InChI
Affinity DataEC50:  220nMAssay Description:Agonist activity at human GPR40 expressed in CHOA12 cells assessed as induction of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6MTMPubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50243999(CHEMBL4061053)copy SMILEScopy InChI
Affinity DataEC50:  3.06E+3nMAssay Description:Agonist activity at human GPR40 expressed in CHOA12 cells assessed as induction of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6MTMPubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50244000(CHEMBL4072314)copy SMILEScopy InChI
Affinity DataEC50:  1.34E+3nMAssay Description:Agonist activity at human GPR40 expressed in CHOA12 cells assessed as induction of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6MTMPubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50244001(CHEMBL4076149)copy SMILEScopy InChI
Affinity DataEC50:  800nMAssay Description:Agonist activity at human GPR40 expressed in CHOA12 cells assessed as induction of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6MTMPubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50244002(CHEMBL4061146)copy SMILEScopy InChI
Affinity DataEC50:  3.62E+3nMAssay Description:Agonist activity at human GPR40 expressed in CHOA12 cells assessed as induction of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6MTMPubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50244003(CHEMBL4067111)copy SMILEScopy InChI
Affinity DataEC50:  2.55E+3nMAssay Description:Agonist activity at human GPR40 expressed in CHOA12 cells assessed as induction of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6MTMPubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50244004(CHEMBL4088375)copy SMILEScopy InChI
Affinity DataEC50:  6.27E+3nMAssay Description:Agonist activity at human GPR40 expressed in CHOA12 cells assessed as induction of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6MTMPubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50244005(CHEMBL4080516)copy SMILEScopy InChI
Affinity DataEC50:  1.18E+3nMAssay Description:Agonist activity at human GPR40 expressed in CHOA12 cells assessed as induction of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6MTMPubMed
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