Compile Data Set for Download or QSAR
Found 85 with Last Name = 'zhang' and Initial = 'jj'
TargetSmoothened homolog(Mus musculus)TBA
LigandPNGBDBM50545020(LY-2940680 | LY2940680 | Taladegib)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMMore data for this Ligand-Target Pair
TargetSmoothened homolog(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545020(LY-2940680 | LY2940680 | Taladegib)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
TargetSmoothened homolog(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249522(2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(me...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
TargetSmoothened homolog(Mus musculus)TBA
LigandPNGBDBM50588429(CHEMBL5182673)copy SMILES
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M98HHPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50559060(CHEMBL4786787)copy SMILES
Affinity DataIC50: 18nMAssay Description:Inhibition of EGFR L858R/T790M/C797S (unknown origin) using Poly (Glu, Tyr) as substrate measured after 40 mins by kinase-glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0RCSPubMed
TargetSmoothened homolog(Mus musculus)TBA
LigandPNGBDBM50588432(CHEMBL5194809)copy SMILES
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M98HHPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Pharmacopeia Drug Discovery, Inc.

Curated by ChEMBL
LigandPNGBDBM50175173(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-chlor...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of CXCL10(IP-10)-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z94GDPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50559059(CHEMBL4752022)copy SMILES
Affinity DataIC50: 22nMAssay Description:Inhibition of EGFR L858R/T790M/C797S (unknown origin) using Poly (Glu, Tyr) as substrate measured after 40 mins by kinase-glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0RCSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545021(CHEMBL4632598)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76H4BPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50559062(CHEMBL4795878)copy SMILES
Affinity DataIC50: 40nMAssay Description:Inhibition of EGFR L858R/T790M/C797S (unknown origin) using Poly (Glu, Tyr) as substrate measured after 40 mins by kinase-glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0RCSPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50559058(CHEMBL4797395)copy SMILES
Affinity DataIC50: 41nMAssay Description:Inhibition of EGFR L858R/T790M/C797S (unknown origin) using Poly (Glu, Tyr) as substrate measured after 40 mins by kinase-glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0RCSPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Pharmacopeia Drug Discovery, Inc.

Curated by ChEMBL
LigandPNGBDBM50175193(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-chlor...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z94GDPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Pharmacopeia Drug Discovery, Inc.

Curated by ChEMBL
LigandPNGBDBM50175183(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-chlor...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z94GDPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Pharmacopeia Drug Discovery, Inc.

Curated by ChEMBL
LigandPNGBDBM50175168(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-chlor...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z94GDPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Pharmacopeia Drug Discovery, Inc.

Curated by ChEMBL
LigandPNGBDBM50175176(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-fluor...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z94GDPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Pharmacopeia Drug Discovery, Inc.

Curated by ChEMBL
LigandPNGBDBM50175173(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-chlor...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z94GDPubMed
TargetSmoothened homolog(Mus musculus)TBA
LigandPNGBDBM50588433(CHEMBL5170628)copy SMILES
Affinity DataIC50: 64nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M98HHPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Pharmacopeia Drug Discovery, Inc.

Curated by ChEMBL
LigandPNGBDBM50175187(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-benzamid...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z94GDPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Pharmacopeia Drug Discovery, Inc.

Curated by ChEMBL
LigandPNGBDBM50175170(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-cyano...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z94GDPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Pharmacopeia Drug Discovery, Inc.

Curated by ChEMBL
LigandPNGBDBM50175173(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-chlor...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of CXCL11-induced CXCR3 mediated T-cell migrationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z94GDPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of EGFR L858R/T790M/C797S (unknown origin) using Poly (Glu, Tyr) as substrate measured after 40 mins by kinase-glo assayMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Pharmacopeia Drug Discovery, Inc.

Curated by ChEMBL
LigandPNGBDBM50175178(4-(4-((4-chlorophenethyl)carbamoyl)-2-(3-chloroben...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z94GDPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50559063(CHEMBL4780903)copy SMILES
Affinity DataIC50: 122nMAssay Description:Inhibition of EGFR L858R/T790M/C797S (unknown origin) using Poly (Glu, Tyr) as substrate measured after 40 mins by kinase-glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0RCSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545030(CHEMBL4644288)copy SMILEScopy InChI
Affinity DataIC50: 123nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76H4BPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Pharmacopeia Drug Discovery, Inc.

Curated by ChEMBL
LigandPNGBDBM50175169(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(thiophe...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z94GDPubMed
TargetSmoothened homolog(Mus musculus)TBA
LigandPNGBDBM50588427(CHEMBL5193213)copy SMILES
Affinity DataIC50: 150nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M98HHPubMed
TargetSmoothened homolog(Mus musculus)TBA
LigandPNGBDBM50588434(CHEMBL5203874)copy SMILES
Affinity DataIC50: 155nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M98HHPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Pharmacopeia Drug Discovery, Inc.

Curated by ChEMBL
LigandPNGBDBM50175185(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-metho...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z94GDPubMed
TargetSmoothened homolog(Mus musculus)TBA
LigandPNGBDBM50588428(CHEMBL5198527)copy SMILES
Affinity DataIC50: 190nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M98HHPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Pharmacopeia Drug Discovery, Inc.

Curated by ChEMBL
LigandPNGBDBM50175164(4-(4-((2-chlorophenethyl)carbamoyl)-2-(3-chloroben...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z94GDPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Pharmacopeia Drug Discovery, Inc.

Curated by ChEMBL
LigandPNGBDBM50175161(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(4-fluor...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z94GDPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Pharmacopeia Drug Discovery, Inc.

Curated by ChEMBL
LigandPNGBDBM50175190(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3,5-dif...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z94GDPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Pharmacopeia Drug Discovery, Inc.

Curated by ChEMBL
LigandPNGBDBM50175177(4-(4-((4-chlorobenzyl)carbamoyl)-2-(3-chlorobenzam...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z94GDPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Pharmacopeia Drug Discovery, Inc.

Curated by ChEMBL
LigandPNGBDBM50175165(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(isonico...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z94GDPubMed
TargetSmoothened homolog(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545025(CHEMBL4635021)copy SMILEScopy InChI
Affinity DataIC50: 285nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76H4BPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Pharmacopeia Drug Discovery, Inc.

Curated by ChEMBL
LigandPNGBDBM50175182(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3,4-dif...)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z94GDPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Pharmacopeia Drug Discovery, Inc.

Curated by ChEMBL
LigandPNGBDBM50175192(4-(4-((3-chlorophenethyl)carbamoyl)-2-(3-chloroben...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z94GDPubMed
TargetSmoothened homolog(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545013(CHEMBL4639888)copy SMILEScopy InChI
Affinity DataIC50: 309nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76H4BPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Pharmacopeia Drug Discovery, Inc.

Curated by ChEMBL
LigandPNGBDBM50175166(4-(4-((4-fluorophenethyl)carbamoyl)-2-(3-chloroben...)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z94GDPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine as substrate assessed as substrate hydrolysis preincubated for 20 mins followed by subst...More data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Pharmacopeia Drug Discovery, Inc.

Curated by ChEMBL
LigandPNGBDBM50175191(4-(4-((2-fluorophenethyl)carbamoyl)-2-(3-chloroben...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z94GDPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Pharmacopeia Drug Discovery, Inc.

Curated by ChEMBL
LigandPNGBDBM50175188(4-(4-((3-fluorophenethyl)carbamoyl)-2-(3-chloroben...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z94GDPubMed
TargetSmoothened homolog(Mus musculus)TBA
LigandPNGBDBM50588430(CHEMBL5203629)copy SMILES
Affinity DataIC50: 409nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M98HHPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Pharmacopeia Drug Discovery, Inc.

Curated by ChEMBL
LigandPNGBDBM50175163(4-(4-((3,4-dimethoxyphenethyl)carbamoyl)-2-(3-chlo...)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z94GDPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Pharmacopeia Drug Discovery, Inc.

Curated by ChEMBL
LigandPNGBDBM50175174(4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(thiophe...)copy SMILEScopy InChI
Affinity DataIC50: 490nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z94GDPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Pharmacopeia Drug Discovery, Inc.

Curated by ChEMBL
LigandPNGBDBM50175171(4-(2-(3-chlorobenzamido)-4-(phenethylcarbamoyl)phe...)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Inhibition of CXCL11-stimulated calcium release in HEK293 cells expressing recombinant human CXCR3 and chimeric G protein Gqi5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z94GDPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50559061(CHEMBL4758107)copy SMILES
Affinity DataIC50: 561nMAssay Description:Inhibition of EGFR L858R/T790M/C797S (unknown origin) using Poly (Glu, Tyr) as substrate measured after 40 mins by kinase-glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0RCSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50545014(CHEMBL4632537)copy SMILEScopy InChI
Affinity DataIC50: 562nMAssay Description:Inhibition of SMO D473H mutant receptor (unknown origin) assessed as inhibition of SAG-induced Hh signaling pathway by Gli luciferase reporter cell-b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76H4BPubMed
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