Compile Data Set for Download or QSAR
Found 350 with Last Name = 'boyer' and Initial = 'jl'
TargetP2X purinoceptor 1(RAT)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50102298(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonomethyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 8.10nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN15HCPubMed
TargetP2X purinoceptor 1(RAT)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50102295(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)copy SMILEScopy InChI
Affinity DataIC50: 9.40nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN15HCPubMed
TargetP2X purinoceptor 1(RAT)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50102299(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonomethyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN15HCPubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Inspire Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50371580(CHEMBL1162175)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Antagonist activity at P2Y12 receptor assessed as inhibition of ADP-induced human platelet aggregation by washed platelet assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55PB6PubMed
TargetP2X purinoceptor 1(RAT)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50102300(CHEMBL331250 | [4-(4-Formyl-5-hydroxy-6-methyl-3-p...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN15HCPubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Inspire Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50371581(CHEMBL1162179)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Antagonist activity at P2Y12 receptor assessed as inhibition of ADP-induced human platelet aggregation by washed platelet assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55PB6PubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Inspire Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50374555(REGRELOR DISODIUM)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Antagonist activity at P2Y12 receptor assessed as platelet aggregation by washed platelet assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM885RPubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Inspire Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50371580(CHEMBL1162175)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Antagonist activity at P2Y12 receptor assessed as inhibition of ADP-induced human platelet aggregation by washed platelet assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55PB6PubMed
TargetP2X purinoceptor 1(RAT)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50102301(4-[4-Formyl-5-hydroxy-6-methyl-3-(2-phosphono-ethy...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN15HCPubMed
TargetP2X purinoceptor 3(RAT)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50102299(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonomethyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of inward ion current elicited by ATP was determined at recombinant P2X3 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN15HCPubMed
TargetP2X purinoceptor 3(RAT)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50102300(CHEMBL331250 | [4-(4-Formyl-5-hydroxy-6-methyl-3-p...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of inward ion current elicited by ATP was determined at recombinant P2X3 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN15HCPubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Inspire Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50371582(CHEMBL1162182)copy SMILEScopy InChI
Affinity DataIC50: 36.2nMAssay Description:Antagonist activity at P2Y12 receptor assessed as inhibition of ADP-induced human platelet aggregation by washed platelet assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55PB6PubMed
TargetP2X purinoceptor 1(RAT)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50102296(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonomethyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN15HCPubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Inspire Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50374558(CHEMBL255350)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Antagonist activity at P2Y12 receptor assessed as platelet aggregation by washed platelet assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM885RPubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Inspire Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50371583(CHEMBL1162184)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Antagonist activity at P2Y12 receptor assessed as inhibition of ADP-induced human platelet aggregation by washed platelet assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55PB6PubMed
TargetP2X purinoceptor 1(RAT)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50102304(CHEMBL116926 | Phosphoric acid mono-(4-formyl-5-hy...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN15HCPubMed
TargetP2X purinoceptor 1(RAT)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50102297(CHEMBL118007 | [2-(3,5-Bis-phosphonomethyl-phenyla...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN15HCPubMed
TargetP2X purinoceptor 1(RAT)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50064800(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN15HCPubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Inspire Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50371589(CHEMBL1162196)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Antagonist activity at P2Y12 receptor assessed as inhibition of ADP-induced human platelet aggregation by washed platelet assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55PB6PubMed
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118238(CHEMBL339873 | MRS 2279)copy SMILEScopy InChI
Affinity DataIC50: 51.6nMAssay Description:Inhibition of 30 nM 2-MeSADP stimulation of 2PY1-mediated phospholipase C (PLC) activity in Turkey erythocyte ghostsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474BJ3PubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Inspire Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50371594(CHEMBL1162161)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Antagonist activity at P2Y12 receptor assessed as inhibition of ADP-induced human platelet aggregation by washed platelet assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55PB6PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118238(CHEMBL339873 | MRS 2279)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Antagonist activity against Turkey erythrocyte P2Y purinoceptor 1 (P2Y1) by the compound is measuredMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9R58PubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Inspire Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50371584(CHEMBL1162185)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Antagonist activity at P2Y12 receptor assessed as inhibition of ADP-induced human platelet aggregation by washed platelet assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55PB6PubMed
TargetP2X purinoceptor 3(RAT)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50064800(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:Inhibition of inward ion current elicited by ATP was determined at recombinant P2X3 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN15HCPubMed
TargetP2X purinoceptor 1(RAT)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)copy SMILEScopy InChI
Affinity DataIC50: 99nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN15HCPubMed
TargetP2X purinoceptor 3(RAT)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50102298(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonomethyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 128nMAssay Description:Inhibition of inward ion current elicited by ATP was determined at recombinant P2X3 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN15HCPubMed
TargetP2X purinoceptor 3(RAT)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50102295(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of inward ion current elicited by ATP was determined at recombinant P2X3 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN15HCPubMed
TargetP2X purinoceptor 3(RAT)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50102301(4-[4-Formyl-5-hydroxy-6-methyl-3-(2-phosphono-ethy...)copy SMILEScopy InChI
Affinity DataIC50: 145nMAssay Description:Inhibition of inward ion current elicited by ATP was determined at recombinant P2X3 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN15HCPubMed
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50085314(CHEMBL350828 | Phosphoric acid mono-[4-(6-methylam...)copy SMILEScopy InChI
Affinity DataIC50: 148nMAssay Description:Inhibition of 30 nM 2-MeSADP stimulation of 2PY1-mediated phospholipase C (PLC) activity in Turkey erythocyte ghostsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474BJ3PubMed
TargetP2X purinoceptor 2(RAT)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50102298(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonomethyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X2 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN15HCPubMed
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50085821(CHEMBL168427 | Phosphoric acid mono-[4-(6-methylam...)copy SMILEScopy InChI
Affinity DataIC50: 157nMAssay Description:Inhibition of 30 nM 2-MeSADP stimulation of 2PY1-mediated phospholipase C (PLC) activity in Turkey erythocyte ghostsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474BJ3PubMed
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076466(2-(6-Methylamino-purin-9-yl)-5,7,9,11-tetraoxo-tet...)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:In vitro antagonist activity at P2Y1 receptor in turkey erythrocyte membranes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9WZMPubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Inspire Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50371585(CHEMBL1162188)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Antagonist activity at P2Y12 receptor assessed as inhibition of ADP-induced human platelet aggregation by washed platelet assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55PB6PubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Inspire Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50374572(CHEMBL403010)copy SMILEScopy InChI
Affinity DataIC50: 201nMAssay Description:Antagonist activity at P2Y12 receptor assessed as platelet aggregation by washed platelet assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM885RPubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076460(CHEMBL288798 | Phosphoric acid mono-[5-(2-chloro-6...)copy SMILEScopy InChI
Affinity DataIC50: 206nMAssay Description:Antagonist activity against Turkey erythrocyte P2Y purinoceptor 1 (P2Y1) by the compound is measuredMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9R58PubMed
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076460(CHEMBL288798 | Phosphoric acid mono-[5-(2-chloro-6...)copy SMILEScopy InChI
Affinity DataIC50: 206nMAssay Description:In vitro antagonist activity at P2Y1 receptor in turkey erythrocyte membranes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9WZMPubMed
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50085322(CHEMBL164811 | Phosphoric acid mono-[5-(2-chloro-6...)copy SMILEScopy InChI
Affinity DataIC50: 206nMAssay Description:Inhibition of 30 nM 2-MeSADP stimulation of 2PY1-mediated phospholipase C (PLC) activity in Turkey erythocyte ghostsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474BJ3PubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Inspire Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50371578(CHEMBL1162172)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Antagonist activity at P2Y12 receptor assessed as inhibition of ADP-induced human platelet aggregation by washed platelet assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55PB6PubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Inspire Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50371577(CHEMBL1162173)copy SMILEScopy InChI
Affinity DataIC50: 211nMAssay Description:Antagonist activity at P2Y12 receptor assessed as inhibition of ADP-induced human platelet aggregation by washed platelet assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55PB6PubMed
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50104022(3-[2-chloro-6-(methylamino)-9H-purin-9-yl]-2-[(pho...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibitory concentration against P2Y1 receptor in turkey erythrocyte membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20864KXPubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Inspire Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50371579(CHEMBL1162171)copy SMILEScopy InChI
Affinity DataIC50: 237nMAssay Description:Antagonist activity at P2Y12 receptor assessed as inhibition of ADP-induced human platelet aggregation by washed platelet assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55PB6PubMed
TargetP2X purinoceptor 3(RAT)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of inward ion current elicited by ATP was determined at recombinant P2X3 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN15HCPubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Inspire Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50374559(CHEMBL255349)copy SMILEScopy InChI
Affinity DataIC50: 243nMAssay Description:Antagonist activity at P2Y12 receptor assessed as platelet aggregation by washed platelet assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM885RPubMed
TargetP2X purinoceptor 2(RAT)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50102299(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonomethyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X2 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN15HCPubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Inspire Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50371576(CHEMBL1162164)copy SMILEScopy InChI
Affinity DataIC50: 288nMAssay Description:Antagonist activity at P2Y12 receptor assessed as inhibition of ADP-induced human platelet aggregation by washed platelet assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55PB6PubMed
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50062291(CHEMBL54116 | Phosphoric acid mono-[2-(6-methylami...)copy SMILEScopy InChI
Affinity DataIC50: 324nMAssay Description:Antagonist activity at P2Y1 receptor measured as capacity to inhibit 50% of phospholipase C stimulation elicited by 10 nM 2-MeSATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SX6DWZPubMed
TargetP2X purinoceptor 3(RAT)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50102296(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonomethyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibition of inward ion current elicited by ATP was determined at recombinant P2X3 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN15HCPubMed
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118229(CHEMBL129841 | MRS 2179)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Antagonist activity at P2Y1 receptor measured as capacity to inhibit 50% of phospholipase C stimulation elicited by 10 nM 2-MeSATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SX6DWZPubMed
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118229(CHEMBL129841 | MRS 2179)copy SMILEScopy InChI
Affinity DataIC50: 331nMAssay Description:In vitro antagonist activity at P2Y1 receptor in turkey erythrocyte membranes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9WZMPubMed
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118229(CHEMBL129841 | MRS 2179)copy SMILEScopy InChI
Affinity DataIC50: 331nMAssay Description:Inhibition of 30 nM 2-MeSADP stimulation of 2PY1-mediated phospholipase C (PLC) activity in Turkey erythocyte ghostsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474BJ3PubMed
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