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Found 44 with Last Name = 'dos santos' and Initial = 'jl'
TargetProtein kinase C gamma type(Homo sapiens (Human))TBA
LigandPNGBDBM50587724(CHEMBL5175742)copy SMILES
Affinity DataKi:  0.650nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q2260PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
S£o Paulo State University

Curated by ChEMBL
LigandPNGBDBM50516759(CHEMBL4458610)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Inhibition of human chymotrypsin-like activity of 20S proteasome (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28055ZMPubMed
TargetBeta-lactamase TEM(Escherichia coli)
S£o Paulo State University

Curated by ChEMBL
LigandPNGBDBM50516761(CHEMBL3286879)copy SMILEScopy InChI
Affinity DataKi:  40nMAssay Description:Inhibition of bacterial beta lactamase TEM-1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28055ZMPubMed
TargetPolyamine deacetylase HDAC10(Mus musculus)
S£o Paulo State University (UNESP)

Curated by ChEMBL
LigandPNGBDBM50531479(CHEMBL4439518)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of mouse liver HDAC using Boc-Lys (Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9SVBPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
S£o Paulo State University

Curated by ChEMBL
LigandPNGBDBM255614(US9499570, D140)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition of full-length human recombinant PDE4B catalytic domain (152 to 484 residues)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28055ZMPubMed
TargetEstrogen receptor(Homo sapiens (Human))
S£o Paulo State University

Curated by ChEMBL
LigandPNGBDBM50516760(CHEMBL4526356)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Selective estrogen receptor down regulator activity at ERalpha (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28055ZMPubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
S£o Paulo State University

Curated by ChEMBL
LigandPNGBDBM50516758(CHEMBL4444471 | US11542283, Compound V-9A)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human chymotrypsin-like activity of 20S proteasome (unknown origin)More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28055ZMPubMed
TargetDecaprenylphosphoryl-beta-D-ribose oxidase(Mycobacterium smegmatis (strain ATCC 700084 / mc(2...)TBA
LigandPNGBDBM50517949(CHEMBL4447540)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR238MPubMed
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))TBA
LigandPNGBDBM50550527(CHEMBL4754902)copy SMILES
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))TBA
LigandPNGBDBM50550519(CHEMBL4755178)copy SMILES
Affinity DataIC50: 27nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q2260PubMed
TargetPolyamine deacetylase HDAC10(Mus musculus)
S£o Paulo State University (UNESP)

Curated by ChEMBL
LigandPNGBDBM50531480(CHEMBL4447524)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of mouse liver HDAC using Boc-Lys (Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9SVBPubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)TBA
LigandPNGBDBM50589215(CHEMBL5190515)copy SMILES
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR238MPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))TBA
LigandPNGBDBM50517949(CHEMBL4447540)copy SMILEScopy InChI
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPolyketide synthase Pks13(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)TBA
LigandPNGBDBM50520948(CHEMBL4443524)copy SMILEScopy InChI
Affinity DataIC50: 190nMMore data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Homo sapiens (Human))TBA
LigandPNGBDBM50598090(CHEMBL5207531)copy SMILES
Affinity DataIC50: 560nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR238MPubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))TBA
LigandPNGBDBM50598090(CHEMBL5207531)copy SMILES
Affinity DataIC50: 560nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR238MPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))TBA
LigandPNGBDBM50598090(CHEMBL5207531)copy SMILES
Affinity DataIC50: 560nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR238MPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
S£o Paulo State University

Curated by ChEMBL
LigandPNGBDBM50516762(CHEMBL4474485)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human neutrophil ElastaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28055ZMPubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))TBA
LigandPNGBDBM50250181(CHEMBL2338421 | N''-(5-Benzofuroxanylmethylidene)I...)copy SMILEScopy InChI
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3NK2PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
São Paulo State University (UNESP) , Institute of Chemistry, Araraquara 14800060, Brazil.

Curated by ChEMBL
LigandPNGBDBM50250181(CHEMBL2338421 | N''-(5-Benzofuroxanylmethylidene)I...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3NK2PubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
São Paulo State University (UNESP) , Institute of Chemistry, Araraquara 14800060, Brazil.

Curated by ChEMBL
LigandPNGBDBM50250181(CHEMBL2338421 | N''-(5-Benzofuroxanylmethylidene)I...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3NK2PubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
São Paulo State University (UNESP) , Institute of Chemistry, Araraquara 14800060, Brazil.

Curated by ChEMBL
LigandPNGBDBM50250181(CHEMBL2338421 | N''-(5-Benzofuroxanylmethylidene)I...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2B6 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3NK2PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
São Paulo State University (UNESP) , Institute of Chemistry, Araraquara 14800060, Brazil.

Curated by ChEMBL
LigandPNGBDBM50598092(CHEMBL4473719)copy SMILES
Affinity DataIC50: 2.50E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR238MPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
São Paulo State University (UNESP) , Institute of Chemistry, Araraquara 14800060, Brazil.

Curated by ChEMBL
LigandPNGBDBM50583310(CHEMBL5082711)copy SMILES
Affinity DataIC50: 3.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR238MPubMed
LigandPNGBDBM50517949(CHEMBL4447540)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR238MPubMed
LigandPNGBDBM50598088(CHEMBL2098221 | GSK3011724A | TCMDC-142399)copy SMILES
Affinity DataIC50: 5.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR238MPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM25150((2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2...)copy SMILEScopy InChI
Affinity DataEC50:  82nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q2260PubMed
TargetHistone deacetylase 7(Homo sapiens (Human))TBA
LigandPNGBDBM25150((2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2...)copy SMILEScopy InChI
Affinity DataEC50:  67nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q2260PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM25150((2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2...)copy SMILEScopy InChI
Affinity DataEC50:  216nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q2260PubMed
TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))TBA
LigandPNGBDBM50396022(CHEMBL2169920)copy SMILEScopy InChI
Affinity DataKd:  5.00E+5nMMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM25150((2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2...)copy SMILEScopy InChI
Affinity DataEC50:  41nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q2260PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))TBA
LigandPNGBDBM25150((2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2...)copy SMILEScopy InChI
Affinity DataEC50:  115nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q2260PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))TBA
LigandPNGBDBM25150((2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2...)copy SMILEScopy InChI
Affinity DataEC50:  30nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q2260PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM25150((2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2...)copy SMILEScopy InChI
Affinity DataEC50:  125nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q2260PubMed
TargetHistone deacetylase 9(Homo sapiens (Human))TBA
LigandPNGBDBM25150((2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2...)copy SMILEScopy InChI
Affinity DataEC50:  128nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q2260PubMed