Compile Data Set for Download or QSAR
Found 147 with Last Name = 'johnson' and Initial = 'jl'
TargetAlpha-galactosidase A(Homo sapiens (Human))
Tottori University , Yonago 683-8503, Japan

LigandPNGBDBM113762(1-Deoxygalactonojirimycin (DGJ) | 2-(hydroxymethyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.780nMpH: 7.0Assay Description:For inhibition assay, 0.1% Triton X-100 extracts were mixed with 4-MU substrates ( 5 mM 4-MU α-ᴅ-galactopyranoside and 0.1 M N-acetyl-J...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5T16PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50229040(CHEMBL156140)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]rolipram binding to Phosphodiesterase 4 in rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WD42SGPubMed
TargetTau-tubulin kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50609151(CHEMBL5283456)copy SMILES
Affinity DataIC50: 1.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetAlpha-galactosidase A(Homo sapiens (Human))
Tottori University , Yonago 683-8503, Japan

LigandPNGBDBM113758(DGJ-pMe SPhT)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMpH: 7.0Assay Description:For inhibition assay, 0.1% Triton X-100 extracts were mixed with 4-MU substrates ( 5 mM 4-MU α-ᴅ-galactopyranoside and 0.1 M N-acetyl-J...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5T16PubMed
TargetTau-tubulin kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50609159(CHEMBL5280210)copy SMILES
Affinity DataIC50: 1.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetTau-tubulin kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50609151(CHEMBL5283456)copy SMILES
Affinity DataIC50: 2.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetTau-tubulin kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50609143(CHEMBL5268795)copy SMILES
Affinity DataIC50: 2.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50229041(CHEMBL351567)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Displacement of [3H]rolipram binding to Phosphodiesterase 4 in rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WD42SGPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Displacement of [3H]rolipram binding to Phosphodiesterase 4 in rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WD42SGPubMed
TargetTau-tubulin kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50609159(CHEMBL5280210)copy SMILES
Affinity DataIC50: 2.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetTau-tubulin kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50609138(CHEMBL5272364)copy SMILES
Affinity DataIC50: 2.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetAlpha-galactosidase A(Homo sapiens (Human))
Tottori University , Yonago 683-8503, Japan

LigandPNGBDBM113762(1-Deoxygalactonojirimycin (DGJ) | 2-(hydroxymethyl...)copy SMILEScopy InChI
Affinity DataIC50: 3nMpH: 5.0Assay Description:For inhibition assay, 0.1% Triton X-100 extracts were mixed with 4-MU substrates ( 5 mM 4-MU α-ᴅ-galactopyranoside and 0.1 M N-acetyl-J...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5T16PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50229038(CHEMBL345917)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Displacement of [3H]rolipram binding to Phosphodiesterase 4 in rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WD42SGPubMed
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50505937(CHEMBL4514925 | US11168095, Example 91)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human ASK1 using myelin basic protein substrate pre-incubated for 20 mins before [33P]-ATP addition and measured after 2 hrs by filter-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50505951(CHEMBL4569388 | US11168095, Example 21)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human ASK1 using myelin basic protein substrate pre-incubated for 20 mins before [33P]-ATP addition and measured after 2 hrs by filter-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6VH5PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50505952(CHEMBL4475667 | US11034671, Example 48 | US1116809...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human ASK1 using myelin basic protein substrate pre-incubated for 20 mins before [33P]-ATP addition and measured after 2 hrs by filter-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6VH5PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50212258(GS-4997 | Selonsertib)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMAssay Description:Inhibition of human ASK1 using myelin basic protein substrate pre-incubated for 20 mins before [33P]-ATP addition and measured after 2 hrs by filter-...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50505960(CHEMBL4456722 | US11168095, Example 39)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human ASK1 using myelin basic protein substrate pre-incubated for 20 mins before [33P]-ATP addition and measured after 2 hrs by filter-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6VH5PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50505954(CHEMBL4562269 | US11168095, Example 97)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human ASK1 using myelin basic protein substrate pre-incubated for 20 mins before [33P]-ATP addition and measured after 2 hrs by filter-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6VH5PubMed
TargetTau-tubulin kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50609144(CHEMBL5279863)copy SMILES
Affinity DataIC50: 7.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50505957(CHEMBL4591648)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human ASK1 using myelin basic protein substrate pre-incubated for 20 mins before [33P]-ATP addition and measured after 2 hrs by filter-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6VH5PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM524903(BDBM50505948 | US11168095, Example 156)copy SMILES
Affinity DataIC50: 8nMAssay Description:Inhibition of human ASK1 using myelin basic protein substrate pre-incubated for 20 mins before [33P]-ATP addition and measured after 2 hrs by filter-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6VH5PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50505956(CHEMBL4473364 | US11168095, Example 28)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human ASK1 using myelin basic protein substrate pre-incubated for 20 mins before [33P]-ATP addition and measured after 2 hrs by filter-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6VH5PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50505939(CHEMBL4542440)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human ASK1 using myelin basic protein substrate pre-incubated for 20 mins before [33P]-ATP addition and measured after 2 hrs by filter-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6VH5PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50505950(CHEMBL4548492 | US11034671, Example 43 | US1116809...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human ASK1 using myelin basic protein substrate pre-incubated for 20 mins before [33P]-ATP addition and measured after 2 hrs by filter-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6VH5PubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
Tottori University , Yonago 683-8503, Japan

LigandPNGBDBM113758(DGJ-pMe SPhT)copy SMILEScopy InChI
Affinity DataIC50: 8.30nMpH: 5.0Assay Description:For inhibition assay, 0.1% Triton X-100 extracts were mixed with 4-MU substrates ( 5 mM 4-MU α-ᴅ-galactopyranoside and 0.1 M N-acetyl-J...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5T16PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50505940(CHEMBL4449840)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human ASK1 using myelin basic protein substrate pre-incubated for 20 mins before [33P]-ATP addition and measured after 2 hrs by filter-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6VH5PubMed
TargetTau-tubulin kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50609137(CHEMBL5282072)copy SMILES
Affinity DataIC50: 9.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetTau-tubulin kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50609160(CHEMBL5268080)copy SMILES
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50505943(CHEMBL4561768 | US11168095, Example 2)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human ASK1 using myelin basic protein substrate pre-incubated for 20 mins before [33P]-ATP addition and measured after 2 hrs by filter-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6VH5PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50023727(CHEMBL3330170)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of V5 tagged human ASK1 expressed in HEK-293T cells assessed as reduction in T838 autophosphorylation incubated for 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6VH5PubMed
TargetTau-tubulin kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50609146(CHEMBL5273263)copy SMILES
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50505959(CHEMBL4442116 | US11168095, Example 89)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human ASK1 using myelin basic protein substrate pre-incubated for 20 mins before [33P]-ATP addition and measured after 2 hrs by filter-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6VH5PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50505945(CHEMBL4462230)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human ASK1 using myelin basic protein substrate pre-incubated for 20 mins before [33P]-ATP addition and measured after 2 hrs by filter-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6VH5PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50218545(Nitraquazone)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Displacement of [3H]rolipram binding to Phosphodiesterase 4 in rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WD42SGPubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
Tottori University , Yonago 683-8503, Japan

LigandPNGBDBM113757(DGJ-pMe OPhT)copy SMILEScopy InChI
Affinity DataIC50: 16nMpH: 7.0Assay Description:For inhibition assay, 0.1% Triton X-100 extracts were mixed with 4-MU substrates ( 5 mM 4-MU α-ᴅ-galactopyranoside and 0.1 M N-acetyl-J...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5T16PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM524905(BDBM50505947 | US11168095, Example 160)copy SMILES
Affinity DataIC50: 17nMAssay Description:Inhibition of human ASK1 using myelin basic protein substrate pre-incubated for 20 mins before [33P]-ATP addition and measured after 2 hrs by filter-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6VH5PubMed
TargetTau-tubulin kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50609146(CHEMBL5273263)copy SMILES
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50505936(CHEMBL4466569)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of human ASK1 using myelin basic protein substrate pre-incubated for 20 mins before [33P]-ATP addition and measured after 2 hrs by filter-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6VH5PubMed
TargetTau-tubulin kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50609145(CHEMBL5271137)copy SMILES
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50212258(GS-4997 | Selonsertib)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of V5 tagged human ASK1 expressed in HEK-293T cells assessed as reduction in T838 autophosphorylation incubated for 1 hrMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50505958(CHEMBL4447729 | US11168095, Example 171)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human ASK1 using myelin basic protein substrate pre-incubated for 20 mins before [33P]-ATP addition and measured after 2 hrs by filter-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6VH5PubMed
TargetTau-tubulin kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50609158(CHEMBL5282902)copy SMILES
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50505952(CHEMBL4475667 | US11034671, Example 48 | US1116809...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of V5 tagged human ASK1 expressed in HEK-293T cells assessed as reduction in T838 autophosphorylation incubated for 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6VH5PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50505951(CHEMBL4569388 | US11168095, Example 21)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of V5 tagged human ASK1 expressed in HEK-293T cells assessed as reduction in T838 autophosphorylation incubated for 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6VH5PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50505955(CHEMBL4544934 | US11168095, Example 4)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of human ASK1 using myelin basic protein substrate pre-incubated for 20 mins before [33P]-ATP addition and measured after 2 hrs by filter-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6VH5PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50505949(CHEMBL4590759 | US11168095, Example 1)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of human ASK1 using myelin basic protein substrate pre-incubated for 20 mins before [33P]-ATP addition and measured after 2 hrs by filter-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6VH5PubMed
TargetTau-tubulin kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50609142(CHEMBL5290581)copy SMILES
Affinity DataIC50: 32nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetTau-tubulin kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50609157(CHEMBL5274162)copy SMILES
Affinity DataIC50: 37nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50505957(CHEMBL4591648)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of V5 tagged human ASK1 expressed in HEK-293T cells assessed as reduction in T838 autophosphorylation incubated for 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6VH5PubMed
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