TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of TACE in NHEK assessed as reduction in LPS/TPA-stimulated TNFalpha production preincubated for 1 hr followed by LPS/TPA stimulation for ...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human TACE catalytic domain using Mca-Pro-Leu-Ala-Gln-Ala-Val-Dpa-Arg-Ser-Ser-Ser-Arg-NH2 as substrate after 2 hrs by fluor...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of MMP12 (unknown origin)More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human TACE catalytic domain using Mca-Pro-Leu-Ala-Gln-Ala-Val-Dpa-Arg-Ser-Ser-Ser-Arg-NH2 as substrate after 2 hrs by fluor...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of MMP12 (unknown origin)More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of TACE in NHEK assessed as reduction in LPS/TPA-stimulated TNFalpha production preincubated for 1 hr followed by LPS/TPA stimulation for ...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 61nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 61nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 68nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 82nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of MMP3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of MMP3 (unknown origin)More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 9(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of ADAM9 (unknown origin)More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of MMP7 (unknown origin)More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of MMP7 (unknown origin)More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 9(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Inhibition of ADAM9 (unknown origin)More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 590nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 720nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 790nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 890nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Nestl� Skin Health R&D
Curated by ChEMBL
Nestl� Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: 950nMAssay Description:Inhibition of ADAM10 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair