Compile Data Set for Download or QSAR
Found 1835 with Last Name = 'ellis' and Initial = 'jm'
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM50075813(CHEMBL3415598)copy SMILEScopy InChI
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of full-length GST-tagged human Syk preincubated for 10 mins followed by peptide substrate/ATP addition measured after 45 mins by TR-FRET ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028T7DPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM50075735(CHEMBL3415583)copy SMILEScopy InChI
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of GST-tagged full length human SYK (1 to 635 end residues) expressed in baculovirus expression system preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB54XRPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM50075735(CHEMBL3415583)copy SMILEScopy InChI
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of full-length GST-tagged human Syk preincubated for 10 mins followed by peptide substrate/ATP addition measured after 45 mins by TR-FRET ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028T7DPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM301997(US9598405, 1.5 | US9598405, 1.6)copy SMILEScopy InChI
Affinity DataIC50: 0.0710nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8V7TUS Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM302002(US9598405, 2.1)copy SMILEScopy InChI
Affinity DataIC50: 0.0720nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8V7TUS Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM302016(US9598405, 3.1)copy SMILEScopy InChI
Affinity DataIC50: 0.0730nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8V7TUS Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM302034(BDBM302035 | US9598405, 4.1)copy SMILEScopy InChI
Affinity DataIC50: 0.0860nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8V7TUS Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM302018(US9598405, 3.3 | US9598405, 3.7)copy SMILEScopy InChI
Affinity DataIC50: 0.0920nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8V7TUS Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM302028(US9598405, 3.13)copy SMILEScopy InChI
Affinity DataIC50: 0.0970nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8V7TUS Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM177763(US9120785, Example 10 | US9120785, Example 11)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMpH: 7.5 T: 2°CAssay Description:Homogeneous Time-Resolved Fluorescence (HTRF) assay for the recombinant human Syk enzyme: A recombinant GST-hSyk fusion protein was used to measure p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959G9CUS Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM50075744(CHEMBL3415594)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of full-length GST-tagged human Syk preincubated for 10 mins followed by peptide substrate/ATP addition measured after 45 mins by TR-FRET ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028T7DPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM50075922(CHEMBL3415606)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of full-length GST-tagged human Syk preincubated for 10 mins followed by peptide substrate/ATP addition measured after 45 mins by TR-FRET ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028T7DPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM50075740(CHEMBL3415589)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of full-length GST-tagged human Syk preincubated for 10 mins followed by peptide substrate/ATP addition measured after 45 mins by TR-FRET ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028T7DPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM301993(BDBM301994 | US9598405, 1.1)copy SMILEScopy InChI
Affinity DataIC50: 0.103nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8V7TUS Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM302029(US9598405, 3.14)copy SMILEScopy InChI
Affinity DataIC50: 0.104nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8V7TUS Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM302032(US9598405, 3.17)copy SMILEScopy InChI
Affinity DataIC50: 0.113nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8V7TUS Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM302000(US9598405, 1.8)copy SMILEScopy InChI
Affinity DataIC50: 0.119nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8V7TUS Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM302030(US9598405, 3.15)copy SMILEScopy InChI
Affinity DataIC50: 0.127nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8V7TUS Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM302013(US9598405, 2.12)copy SMILEScopy InChI
Affinity DataIC50: 0.152nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8V7TUS Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM302017(US9598405, 3.2 | US9598405, 3.6)copy SMILEScopy InChI
Affinity DataIC50: 0.158nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8V7TUS Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM302033(US9598405, 3.18)copy SMILEScopy InChI
Affinity DataIC50: 0.160nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8V7TUS Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM302042(US9598405, 5.1)copy SMILEScopy InChI
Affinity DataIC50: 0.161nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8V7TUS Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM301996(US9598405, 1.4)copy SMILEScopy InChI
Affinity DataIC50: 0.164nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8V7TUS Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM340000(5-{[(3R,4R)-3- aminotetrahydro-2H-pyran-4- yl]amin...)copy SMILES
Affinity DataIC50: 0.200nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RN9US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM339977(5-{[(1R,2S)-2-aminocyclohexyl]amino}-3-(5-chloro-1...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RN9US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM50075747(CHEMBL3415597)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of full-length GST-tagged human Syk preincubated for 10 mins followed by peptide substrate/ATP addition measured after 45 mins by TR-FRET ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028T7DPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM302026(US9598405, 3.11)copy SMILEScopy InChI
Affinity DataIC50: 0.208nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8V7TUS Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM302036(BDBM302037 | US9598405, 4.3)copy SMILEScopy InChI
Affinity DataIC50: 0.228nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8V7TUS Patent
LigandPNGBDBM50590228(CHEMBL5172416)copy SMILES
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2TZ3PubMed
LigandPNGBDBM50609728(CHEMBL5267350)copy SMILES
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50609742(CHEMBL5286106)copy SMILES
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50609742(CHEMBL5286106)copy SMILES
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM340008((S)-5-((2-Aminopropyl)amino)-3-(5-(pyridin-3-yl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RN9US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM302006(US9598405, 2.5)copy SMILEScopy InChI
Affinity DataIC50: 0.316nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8V7TUS Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM302014(US9598405, 2.13)copy SMILEScopy InChI
Affinity DataIC50: 0.333nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8V7TUS Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM302039(US9598405, 4.6)copy SMILEScopy InChI
Affinity DataIC50: 0.392nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8V7TUS Patent
LigandPNGBDBM50609741(CHEMBL5284341)copy SMILES
Affinity DataIC50: 0.400nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM50075819(CHEMBL3415604)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of full-length GST-tagged human Syk preincubated for 10 mins followed by peptide substrate/ATP addition measured after 45 mins by TR-FRET ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028T7DPubMed
LigandPNGBDBM50590227(CHEMBL5181104)copy SMILES
Affinity DataIC50: 0.400nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2TZ3PubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM339978(5-{[(2S)-2- aminopropyl]amino}-3-(4- bromo-1H-indo...)copy SMILES
Affinity DataIC50: 0.400nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RN9US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM182098(US9145391, 3-2 | US9145391, 3-3)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSyk fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-Syk (Carna Bi...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8Z5VUS Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM50075732(CHEMBL3414584 | US9775839, 2.1)copy SMILES
Affinity DataIC50: 0.5nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RN9US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM339979(5-[(3-aminotetrahydro-2H- pyran-4-yl)amino]-3-(4- ...)copy SMILES
Affinity DataIC50: 0.5nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RN9US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM339998(5-{[(3R,4R)-3- aminotetrahydro-2H-pyran-4- yl]amin...)copy SMILES
Affinity DataIC50: 0.5nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RN9US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM339999(5-{[(3R,4R)-3- aminotetrahydro-2H-pyran-4- yl]amin...)copy SMILES
Affinity DataIC50: 0.5nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MG7RN9US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM177763(US9120785, Example 10 | US9120785, Example 11)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:Homogeneous Time-Resolved Fluorescence (HTRF) assay for the recombinant human Syk enzyme: A recombinant GST-hSyk fusion protein was used to measure p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959G9CUS Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM177765(US9120785, Example 14 Step 2)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:Homogeneous Time-Resolved Fluorescence (HTRF) assay for the recombinant human Syk enzyme: A recombinant GST-hSyk fusion protein was used to measure p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959G9CUS Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM177767(US9120785, Example 14-4)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:Homogeneous Time-Resolved Fluorescence (HTRF) assay for the recombinant human Syk enzyme: A recombinant GST-hSyk fusion protein was used to measure p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959G9CUS Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck & Co., Inc.

Curated by ChEMBL
LigandPNGBDBM177768(US9120785, Example 14-14)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:Homogeneous Time-Resolved Fluorescence (HTRF) assay for the recombinant human Syk enzyme: A recombinant GST-hSyk fusion protein was used to measure p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2959G9CUS Patent
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