Compile Data Set for Download or QSAR
Found 434 with Last Name = 'onorato' and Initial = 'jm'
TargetApelin receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50588316(CHEMBL5170657)copy SMILES
Affinity DataKi:  0.0700nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5JX5PubMed
TargetApelin receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50567169(CHEMBL4873876)copy SMILES
Affinity DataKi:  0.0740nMAssay Description:Displacement of [3H]Apelin-13 from human APJ receptor stably expressed in human HEK293 cell membrane incubated for 120 mins by TopCount scintillation...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3PXZPubMed
TargetApelin receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50014619(CHEMBL3184840)copy SMILEScopy InChI
Affinity DataKi:  0.170nMAssay Description:Displacement of [3H]Apelin-13 from human APJ receptor stably expressed in human HEK293 cell membrane incubated for 120 mins by TopCount scintillation...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3PXZPubMed
TargetEndothelial lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506506(CHEMBL4465833)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of EL in human HT1080 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8PZSPubMed
TargetEndothelial lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506498(CHEMBL4581886)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of EL in human HT1080 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8PZSPubMed
TargetEndothelial lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506505(CHEMBL4460376)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of EL in human HT1080 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8PZSPubMed
TargetEndothelial lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506504(CHEMBL4460663)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of EL in human HT1080 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8PZSPubMed
TargetEndothelial lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506501(CHEMBL4563019)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of EL in human HT1080 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8PZSPubMed
TargetMyeloperoxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50554034(CHEMBL4747269)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEndothelial lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506500(CHEMBL4471611)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of EL in human HT1080 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8PZSPubMed
TargetMyeloperoxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50554035(CHEMBL4790231)copy SMILES
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMyeloperoxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50554052(CHEMBL4763667)copy SMILES
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506499(CHEMBL4463265)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human HL expressed in human COS7 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8PZSPubMed
TargetMyeloperoxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50554050(CHEMBL4752248)copy SMILES
Affinity DataIC50: 2.90nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4829PubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM187287(US9169240, 27)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human HL expressed in human COS7 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8PZSPubMed
TargetEndothelial lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM205027(US9249096, 40)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9T2RPubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506506(CHEMBL4465833)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human HL expressed in human COS7 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8PZSPubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506505(CHEMBL4460376)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human HL expressed in human COS7 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8PZSPubMed
TargetMyeloperoxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50554057(CHEMBL4740830)copy SMILES
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4829PubMed
TargetEndothelial lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506499(CHEMBL4463265)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of EL in human HT1080 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8PZSPubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM187290(US9169240, 30)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human HL expressed in human COS7 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8PZSPubMed
TargetEndothelial lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50458638(CHEMBL4203395)copy SMILEScopy InChI
Affinity DataIC50: 5.40nMAssay Description:Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9T2RPubMed
TargetMyeloperoxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50554056(CHEMBL4782307)copy SMILES
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4829PubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506500(CHEMBL4471611)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human HL expressed in human COS7 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8PZSPubMed
TargetMyeloperoxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50554054(CHEMBL4751166)copy SMILES
Affinity DataIC50: 9.30nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4829PubMed
TargetEndothelial lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM187290(US9169240, 30)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of EL in human HT1080 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addition and measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8PZSPubMed
TargetEndothelial lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM187289(US9169240, 29)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of EL in human HT1080 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addition and measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8PZSPubMed
TargetEndothelial lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50458637(CHEMBL4210998)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9T2RPubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506497(CHEMBL4446812)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human HL expressed in human COS7 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8PZSPubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM187310(US9169240, 49)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human HL expressed in human COS7 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8PZSPubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM187289(US9169240, 29)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human HL expressed in human COS7 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8PZSPubMed
TargetMyeloperoxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50554051(CHEMBL4795827)copy SMILES
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4829PubMed
TargetMyeloperoxidase(Homo sapiens (Human))TBA
LigandPNGBDBM357630(7-(3- chlorobenzyl)- 3H- [1,2,3]triazolo [4,5-b]py...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 240 mM NaCl and 10 uM H2O2 by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4829PubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50458647(CHEMBL4212095)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human HL expressed in African green monkey COS7 cells using HDL as substrate pretreated for 10 mins followed by substrate a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9T2RPubMed
TargetEndothelial lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506741(CHEMBL4513722)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human endothelial lipase expressed in African green monkey COS7 cells using HDL as substrate pretreated for 10 mins followe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9TQ8PubMed
TargetMyeloperoxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50554036(CHEMBL4764237)copy SMILES
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins by amplex red dye based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4829PubMed
TargetMyeloperoxidase(Homo sapiens (Human))TBA
LigandPNGBDBM357653(3-((5-amino- 3H- [1,2,3]triazolo [4,5-b] pyridin- ...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 240 mM NaCl and 10 uM H2O2 by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4829PubMed
TargetEndothelial lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50458645(CHEMBL4215063)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9T2RPubMed
TargetEndothelial lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50458642(CHEMBL4218352)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9T2RPubMed
TargetMyeloperoxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50554055(CHEMBL4755252)copy SMILES
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4829PubMed
TargetEndothelial lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506497(CHEMBL4446812)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of EL in human HT1080 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8PZSPubMed
TargetEndothelial lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506502(CHEMBL4575712)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of EL in human HT1080 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8PZSPubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506503(CHEMBL4475891)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human HL expressed in human COS7 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8PZSPubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506498(CHEMBL4581886)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human HL expressed in human COS7 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8PZSPubMed
TargetEndothelial lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506500(CHEMBL4471611)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of EL in human HT1080 cells using D31-POPC-HDL as substrate incubated for 2 hrs in presence of human serum by LC/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8PZSPubMed
TargetEndothelial lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506501(CHEMBL4563019)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of EL in human HT1080 cells using D31-POPC-HDL as substrate incubated for 2 hrs in presence of human serum by LC/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8PZSPubMed
TargetEndothelial lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM187287(US9169240, 27)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of EL in human HT1080 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addition and measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8PZSPubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506504(CHEMBL4460663)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human HL expressed in human COS7 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8PZSPubMed
TargetEndothelial lipase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50506738(CHEMBL4558644)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human endothelial lipase expressed in African green monkey COS7 cells using HDL as substrate pretreated for 10 mins followe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9TQ8PubMed
TargetMyeloperoxidase(Homo sapiens (Human))TBA
LigandPNGBDBM357629(7-benzyl-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine ...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 240 mM NaCl and 10 uM H2O2 by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4829PubMed
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