Compile Data Set for Download or QSAR
Found 38 with Last Name = 'ruxer' and Initial = 'jm'
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Hoechst Marion Roussel Deutschland GmhH

Curated by ChEMBL
LigandPNGBDBM50085011(2-Benzyloxycarbonylamino-3-(2-{(S)-4-[3-(4,5-dihyd...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of Kistrin binding to integrin alphaV-beta3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290249VPubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357454(CHEMBL1917878)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Hoechst Marion Roussel Deutschland GmhH

Curated by ChEMBL
LigandPNGBDBM50085018(3-(2-{(S)-4-[3-(1H-Benzoimidazol-2-ylamino)-propyl...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of Kistrin binding to integrin alphaV-beta3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290249VPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Hoechst Marion Roussel Deutschland GmhH

Curated by ChEMBL
LigandPNGBDBM50085015(2-Benzyloxycarbonylamino-3-{2-[(S)-4-(3-guanidino-...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of Kistrin binding to integrin alphaV-beta3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290249VPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Hoechst Marion Roussel Deutschland GmhH

Curated by ChEMBL
LigandPNGBDBM50085019(2-(3-Benzyl-ureido)-3-{2-[(S)-4-(3-guanidino-propy...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of Kistrin binding to integrin alphaV-beta3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290249VPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Hoechst Marion Roussel Deutschland GmhH

Curated by ChEMBL
LigandPNGBDBM50085006(2-Benzyloxycarbonylamino-3-{2-[(S)-4-(4-guanidino-...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of Kistrin binding to integrin alphaV-beta3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290249VPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Hoechst Marion Roussel Deutschland GmhH

Curated by ChEMBL
LigandPNGBDBM50085010(3-{2-[(S)-4-(3-Guanidino-propyl)-2,5-dioxo-imidazo...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of Kistrin binding to integrin alphaV-beta3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290249VPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Hoechst Marion Roussel Deutschland GmhH

Curated by ChEMBL
LigandPNGBDBM50085010(3-{2-[(S)-4-(3-Guanidino-propyl)-2,5-dioxo-imidazo...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of Kistrin binding to integrin alphaV-beta3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290249VPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Hoechst Marion Roussel Deutschland GmhH

Curated by ChEMBL
LigandPNGBDBM50085008(3-{2-[(S)-4-(3-Guanidino-propyl)-2,5-dioxo-imidazo...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of Kistrin binding to integrin alphaV-beta3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290249VPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Hoechst Marion Roussel Deutschland GmhH

Curated by ChEMBL
LigandPNGBDBM50085012(2-(Butane-1-sulfonylamino)-3-{2-[(S)-4-(3-guanidin...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of Kistrin binding to integrin alphaV-beta3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290249VPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Hoechst Marion Roussel Deutschland GmhH

Curated by ChEMBL
LigandPNGBDBM50085008(3-{2-[(S)-4-(3-Guanidino-propyl)-2,5-dioxo-imidazo...)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:Inhibition of fibrinogen binding to integrin alphaIIb-beta3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290249VPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Hoechst Marion Roussel Deutschland GmhH

Curated by ChEMBL
LigandPNGBDBM50085019(2-(3-Benzyl-ureido)-3-{2-[(S)-4-(3-guanidino-propy...)copy SMILEScopy InChI
Affinity DataIC50: 570nMAssay Description:Inhibition of Kistrin binding to integrin alphaV-beta3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290249VPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Hoechst Marion Roussel Deutschland GmhH

Curated by ChEMBL
LigandPNGBDBM50085007(2-Benzyloxycarbonylamino-3-(2-{(S)-4-[N'-(4,5-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 580nMAssay Description:Inhibition of Kistrin binding to integrin alphaV-beta3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290249VPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Hoechst Marion Roussel Deutschland GmhH

Curated by ChEMBL
LigandPNGBDBM50085012(2-(Butane-1-sulfonylamino)-3-{2-[(S)-4-(3-guanidin...)copy SMILEScopy InChI
Affinity DataIC50: 760nMAssay Description:Inhibition of Kistrin binding to integrin alphaV-beta3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290249VPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Hoechst Marion Roussel Deutschland GmhH

Curated by ChEMBL
LigandPNGBDBM50085006(2-Benzyloxycarbonylamino-3-{2-[(S)-4-(4-guanidino-...)copy SMILEScopy InChI
Affinity DataIC50: 850nMAssay Description:Inhibition of fibrinogen binding to integrin alphaIIb-beta3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290249VPubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357460(CHEMBL1917729)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357459(CHEMBL1917728)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4XH4PubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357458(CHEMBL1917727)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Hoechst Marion Roussel Deutschland GmhH

Curated by ChEMBL
LigandPNGBDBM50085014(2-Benzyloxycarbonylamino-3-(2-{(S)-2,5-dioxo-4-[3-...)copy SMILEScopy InChI
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of Kistrin binding to integrin alphaV-beta3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290249VPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Hoechst Marion Roussel Deutschland GmhH

Curated by ChEMBL
LigandPNGBDBM50085015(2-Benzyloxycarbonylamino-3-{2-[(S)-4-(3-guanidino-...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of Kistrin binding to integrin alphaV-beta3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290249VPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Hoechst Marion Roussel Deutschland GmhH

Curated by ChEMBL
LigandPNGBDBM50085017(2-(3-Benzyl-thioureido)-3-{2-[(S)-4-(3-guanidino-p...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Kistrin binding to integrin alphaV-beta3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290249VPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Hoechst Marion Roussel Deutschland GmhH

Curated by ChEMBL
LigandPNGBDBM50085016(2-Benzyloxycarbonylamino-3-{2-[(S)-4-(2-guanidino-...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Kistrin binding to integrin alphaV-beta3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290249VPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Hoechst Marion Roussel Deutschland GmhH

Curated by ChEMBL
LigandPNGBDBM50085013(3-[2-((S)-4-{[(1H-Benzoimidazol-2-ylmethyl)-carbam...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of fibrinogen binding to integrin alphaIIb-beta3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290249VPubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357461(CHEMBL1917723)copy SMILEScopy InChI
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of human Hsp90beta after overnight incubation by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Hoechst Marion Roussel Deutschland GmhH

Curated by ChEMBL
LigandPNGBDBM50085017(2-(3-Benzyl-thioureido)-3-{2-[(S)-4-(3-guanidino-p...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Kistrin binding to integrin alphaV-beta3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290249VPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Hoechst Marion Roussel Deutschland GmhH

Curated by ChEMBL
LigandPNGBDBM50085018(3-(2-{(S)-4-[3-(1H-Benzoimidazol-2-ylamino)-propyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Kistrin binding to integrin alphaV-beta3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290249VPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Hoechst Marion Roussel Deutschland GmhH

Curated by ChEMBL
LigandPNGBDBM50085009(2-Benzyloxycarbonylamino-3-[2-((S)-4-guanidinometh...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Kistrin binding to integrin alphaV-beta3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290249VPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Hoechst Marion Roussel Deutschland GmhH

Curated by ChEMBL
LigandPNGBDBM50085016(2-Benzyloxycarbonylamino-3-{2-[(S)-4-(2-guanidino-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of fibrinogen binding to integrin alphaIIb-beta3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290249VPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Hoechst Marion Roussel Deutschland GmhH

Curated by ChEMBL
LigandPNGBDBM50085007(2-Benzyloxycarbonylamino-3-(2-{(S)-4-[N'-(4,5-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of fibrinogen binding to integrin alphaIIb-beta3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290249VPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Hoechst Marion Roussel Deutschland GmhH

Curated by ChEMBL
LigandPNGBDBM50085011(2-Benzyloxycarbonylamino-3-(2-{(S)-4-[3-(4,5-dihyd...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of fibrinogen binding to integrin alphaIIb-beta3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290249VPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Hoechst Marion Roussel Deutschland GmhH

Curated by ChEMBL
LigandPNGBDBM50085014(2-Benzyloxycarbonylamino-3-(2-{(S)-2,5-dioxo-4-[3-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of fibrinogen binding to integrin alphaIIb-beta3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290249VPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Hoechst Marion Roussel Deutschland GmhH

Curated by ChEMBL
LigandPNGBDBM50085013(3-[2-((S)-4-{[(1H-Benzoimidazol-2-ylmethyl)-carbam...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of Kistrin binding to integrin alphaV-beta3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290249VPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Hoechst Marion Roussel Deutschland GmhH

Curated by ChEMBL
LigandPNGBDBM50085009(2-Benzyloxycarbonylamino-3-[2-((S)-4-guanidinometh...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of Kistrin binding to integrin alphaV-beta3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q290249VPubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357455(CHEMBL1917724)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357457(CHEMBL1917726)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357456(CHEMBL1917725)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4XH4PubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357454(CHEMBL1917878)copy SMILEScopy InChI
Affinity DataKd:  0.350nMAssay Description:Binding affinity to human Hsp90beta after overnight incubation by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM15359((4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-...)copy SMILEScopy InChI
Affinity DataKd:  7.30nMAssay Description:Binding affinity to human Hsp90beta after overnight incubation by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4XH4PubMed