Compile Data Set for Download or QSAR
Found 66 with Last Name = 'dunn' and Initial = 'jp'
TargetCytochrome P450 2C9(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50440019(CHEMBL2425654)copy SMILEScopy InChI
Affinity DataIC50: 7.80nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20003HKPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50440017(CHEMBL2425651)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20003HKPubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:In vitro inhibition of rabbit lens aldose reductase.More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50262376(6-((7-(3-chlorobenzyl)benzofuran-5-yl)methyl)pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FC6PubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022273(2-(4-Hydroxy-5-oxo-10,11-dihydro-5H-dibenzo[a,d]cy...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:In vitro inhibition of rabbit lens aldose reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0RWWPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50261746(3-chloro-5-(6-chloro-2-fluoro-3-((6-methyl-5-oxo-5...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5GG4PubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022265((11-Oxo-6,11-dihydro-dibenzo[b,e]oxepin-3-yl)-acet...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:In vitro inhibition of rabbit lens aldose reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0RWWPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50262377(6-((7-(3-chlorophenoxy)benzofuran-5-yl)methyl)pyri...)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Inhibition of recombinant CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FC6PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50262375(6-((7-(3-chlorobenzoyl)benzofuran-5-yl)methyl)pyri...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of recombinant CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FC6PubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022274((5-Oxo-5,11-dihydro-10-thia-dibenzo[a,d]cyclohepte...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:In vitro inhibition of rabbit lens aldose reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0RWWPubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022263((4-Hydroxy-5-oxo-5H-dibenzo[a,d]cyclohepten-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 760nMAssay Description:In vitro inhibition of rabbit lens aldose reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0RWWPubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022260(11,12-Dihydro-3H-1-oxa-benzo[4,5]cyclohepta[1,2-e]...)copy SMILEScopy InChI
Affinity DataIC50: 770nMAssay Description:In vitro inhibition of rabbit lens aldose reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0RWWPubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022264((7-Hydroxy-5-oxo-10,11-dihydro-5H-dibenzo[a,d]cycl...)copy SMILEScopy InChI
Affinity DataIC50: 830nMAssay Description:In vitro inhibition of rabbit lens aldose reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0RWWPubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022268((5-Oxo-5H-dibenzo[a,d]cyclohepten-2-yl)-acetic aci...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of rabbit lens aldose reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0RWWPubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50440020(CHEMBL2425655)copy SMILEScopy InChI
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of human recombinant human CDK1/GST-tagged cyclin B expressed in baculovirus infected insect cells assessed as inhibition of 6XHis-tagged ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20003HKPubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022262(2-(4-Hydroxy-5-oxo-5H-dibenzo[a,d]cyclohepten-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:In vitro inhibition of rabbit lens aldose reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0RWWPubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022266(2-(5-Oxo-5H-dibenzo[a,d]cyclohepten-2-yl)-propioni...)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+3nMAssay Description:In vitro inhibition of rabbit lens aldose reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0RWWPubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022270((1-Hydroxy-5-oxo-10,11-dihydro-5H-dibenzo[a,d]cycl...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro inhibition of rabbit lens aldose reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0RWWPubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:In vitro inhibition of rabbit lens aldose reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0RWWPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50262487(3-(6-chloro-2-fluoro-3-((5-methyl-6-oxo-1,6-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FC6PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50261877(3-chloro-5-(2-fluoro-6-methyl-3-((4-methyl-5-oxo-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5GG4PubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50262487(3-(6-chloro-2-fluoro-3-((5-methyl-6-oxo-1,6-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FC6PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50262487(3-(6-chloro-2-fluoro-3-((5-methyl-6-oxo-1,6-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of recombinant CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FC6PubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50262487(3-(6-chloro-2-fluoro-3-((5-methyl-6-oxo-1,6-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FC6PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50262487(3-(6-chloro-2-fluoro-3-((5-methyl-6-oxo-1,6-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FC6PubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibition of rabbit lens aldose reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0RWWPubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022272((8-Hydroxy-5-oxo-10,11-dihydro-5H-dibenzo[a,d]cycl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibition of rabbit lens aldose reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0RWWPubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022269((4-Hydroxy-5-oxo-10,11-dihydro-5H-dibenzo[a,d]cycl...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+5nMAssay Description:In vitro inhibition of rabbit lens aldose reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0RWWPubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022261((5-Oxo-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-2-...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+5nMAssay Description:In vitro inhibition of rabbit lens aldose reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0RWWPubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022271(2-(3-Benzoylphenyl)propionic acid | 2-(3-benzoylph...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+5nMAssay Description:In vitro inhibition of rabbit lens aldose reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0RWWPubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022267((6-Hydroxy-5-oxo-10,11-dihydro-5H-dibenzo[a,d]cycl...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+5nMAssay Description:In vitro inhibition of rabbit lens aldose reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0RWWPubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM26193(2-Hydroxybenzoate, I | 2-hydroxybenzoic acid | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+6nMAssay Description:In vitro inhibition of rabbit lens aldose reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0RWWPubMed
TargetMitogen-activated protein kinase 4(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50440018(CHEMBL2425628)copy SMILEScopy InChI
Affinity DataKd:  1.10E+4nMAssay Description:Binding affinity to ERK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20003HKPubMed
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50440018(CHEMBL2425628)copy SMILEScopy InChI
Affinity DataKd:  330nMAssay Description:Binding affinity to ERK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20003HKPubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50440018(CHEMBL2425628)copy SMILEScopy InChI
Affinity DataKd:  1.50E+3nMAssay Description:Binding affinity to ERK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20003HKPubMed
TargetSerine/threonine-protein kinase 17A(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50440018(CHEMBL2425628)copy SMILEScopy InChI
Affinity DataKd:  440nMAssay Description:Binding affinity to DRAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20003HKPubMed
TargetSerine/threonine-protein kinase DCLK3(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50440018(CHEMBL2425628)copy SMILEScopy InChI
Affinity DataKd:  1.80E+3nMAssay Description:Binding affinity to DCAMKL3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20003HKPubMed
TargetDeath-associated protein kinase 3(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50440018(CHEMBL2425628)copy SMILEScopy InChI
Affinity DataKd:  880nMAssay Description:Binding affinity to DAPK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20003HKPubMed
TargetDeath-associated protein kinase 2(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50440018(CHEMBL2425628)copy SMILEScopy InChI
Affinity DataKd:  1.30E+3nMAssay Description:Binding affinity to DAPK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20003HKPubMed
TargetDeath-associated protein kinase 1(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50440018(CHEMBL2425628)copy SMILEScopy InChI
Affinity DataKd:  380nMAssay Description:Binding affinity to DAPK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20003HKPubMed
TargetCitron Rho-interacting kinase(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50440018(CHEMBL2425628)copy SMILEScopy InChI
Affinity DataKd:  2.70E+3nMAssay Description:Binding affinity to CIT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20003HKPubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50440018(CHEMBL2425628)copy SMILEScopy InChI
Affinity DataKd:  620nMAssay Description:Binding affinity to CDK7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20003HKPubMed
TargetCyclin-dependent kinase 11A(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50440018(CHEMBL2425628)copy SMILEScopy InChI
Affinity DataKd:  2.40E+3nMAssay Description:Binding affinity to CDC2L2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20003HKPubMed
TargetCyclin-dependent kinase 11B(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50440018(CHEMBL2425628)copy SMILEScopy InChI
Affinity DataKd:  1.30E+3nMAssay Description:Binding affinity to CDC2L1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20003HKPubMed
TargetCalcium/calmodulin-dependent protein kinase type 1G(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50440018(CHEMBL2425628)copy SMILEScopy InChI
Affinity DataKd:  4.20E+3nMAssay Description:Binding affinity to CAMK1G (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20003HKPubMed
TargetCalcium/calmodulin-dependent protein kinase type 1D(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50440018(CHEMBL2425628)copy SMILEScopy InChI
Affinity DataKd:  2.80E+3nMAssay Description:Binding affinity to CAMK1D (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20003HKPubMed
TargetCalcium/calmodulin-dependent protein kinase type 1(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50440018(CHEMBL2425628)copy SMILEScopy InChI
Affinity DataKd:  4.30E+3nMAssay Description:Binding affinity to CAMK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20003HKPubMed
TargetAtypical kinase COQ8B, mitochondrial(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50440018(CHEMBL2425628)copy SMILEScopy InChI
Affinity DataKd:  4.80E+3nMAssay Description:Binding affinity to ADCK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20003HKPubMed
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50440018(CHEMBL2425628)copy SMILEScopy InChI
Affinity DataKd:  1.50E+3nMAssay Description:Binding affinity to ERK5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20003HKPubMed
TargetMitogen-activated protein kinase 15(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50440018(CHEMBL2425628)copy SMILEScopy InChI
Affinity DataKd:  650nMAssay Description:Binding affinity to ERK8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20003HKPubMed
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