Found 45 with Last Name = 'maianti' and Initial = 'jp' TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 54nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 60nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 60nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 60nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 60nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 60nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 60nMAssay Description:In vitro protease assays: Protease assays with IDE and neprilysin were performed using Mca-RPPGFSAFK(Dnp)-OH substrate peptide (R&D Systems, SEQ ID N...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 65nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 80nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 85nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Mus musculus (Mouse))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 90nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Mus musculus (Mouse))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 90nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 100nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 150nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 370nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 500nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 570nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 1.00E+3nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro protease assays: Protease assays with IDE and neprilysin were performed using Mca-RPPGFSAFK(Dnp)-OH substrate peptide (R&D Systems, SEQ ID N...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 1.50E+3nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 1.50E+3nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro protease assays: Protease assays with IDE and neprilysin were performed using Mca-RPPGFSAFK(Dnp)-OH substrate peptide (R&D Systems, SEQ ID N...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 2.10E+3nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 3.20E+3nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 5.00E+3nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 5.60E+3nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 5.60E+3nMAssay Description:In vitro protease assays: Protease assays with IDE and neprilysin were performed using Mca-RPPGFSAFK(Dnp)-OH substrate peptide (R&D Systems, SEQ ID N...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 6.00E+3nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 7.00E+3nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro protease assays: Protease assays with IDE and neprilysin were performed using Mca-RPPGFSAFK(Dnp)-OH substrate peptide (R&D Systems, SEQ ID N...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 1.00E+4nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 1.00E+4nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 1.00E+4nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 2.00E+4nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 2.00E+4nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 2.00E+4nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 2.00E+4nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 2.00E+4nMAssay Description:In vitro protease assays: Protease assays with IDE and neprilysin were performed using Mca-RPPGFSAFK(Dnp)-OH substrate peptide (R&D Systems, SEQ ID N...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 2.00E+4nMAssay Description:In vitro protease assays: Protease assays with IDE and neprilysin were performed using Mca-RPPGFSAFK(Dnp)-OH substrate peptide (R&D Systems, SEQ ID N...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro protease assays: Protease assays with IDE and neprilysin were performed using Mca-RPPGFSAFK(Dnp)-OH substrate peptide (R&D Systems, SEQ ID N...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro protease assays: Protease assays with IDE and neprilysin were performed using Mca-RPPGFSAFK(Dnp)-OH substrate peptide (R&D Systems, SEQ ID N...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 1.00E+5nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 1.00E+5nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 1.00E+5nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
President and Fellows of Harvard College
US Patent
President and Fellows of Harvard College
US Patent
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro protease assays: Protease assays with IDE and neprilysin were performed using Mca-RPPGFSAFK(Dnp)-OH substrate peptide (R&D Systems, SEQ ID N...More data for this Ligand-Target Pair
