Compile Data Set for Download or QSAR
Found 92 with Last Name = 'umland' and Initial = 'jp'
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM50176377((R)-2-(4-fluorophenoxy)-N-(1-(thiophen-2-yl)ethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of PDE4DMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348JXPPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM50176377((R)-2-(4-fluorophenoxy)-N-(1-(thiophen-2-yl)ethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of PAF mediated human eosinophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348JXPPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM50176377((R)-2-(4-fluorophenoxy)-N-(1-(thiophen-2-yl)ethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of C5a mediated human eosinophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348JXPPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM50176377((R)-2-(4-fluorophenoxy)-N-(1-(thiophen-2-yl)ethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of release of LTE4 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348JXPPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM50176377((R)-2-(4-fluorophenoxy)-N-(1-(thiophen-2-yl)ethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of Eotaxin mediated by human eosinophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348JXPPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Mus musculus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50470784(CHEMBL282934)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]rolipram from mouse brain homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P12Q4PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Mus musculus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50470788(CHEMBL278386)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]rolipram from mouse brain homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P12Q4PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM50176377((R)-2-(4-fluorophenoxy)-N-(1-(thiophen-2-yl)ethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of PDE4DMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348JXPPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Mus musculus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]rolipram from mouse brain homogenatesMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Mus musculus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50470782(CHEMBL280185)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]rolipram from mouse brain homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P12Q4PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibitory activity on human eosinophil phosphodiesterase 4.More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Mus musculus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50470786(CHEMBL21964)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Displacement of [3H]rolipram from mouse brain homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P12Q4PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of PDE4AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348JXPPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Mus musculus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50470781(CHEMBL281781)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]rolipram from mouse brain homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P12Q4PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Mus musculus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50470779(CHEMBL21463)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]rolipram from mouse brain homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P12Q4PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50471675(CHEMBL307678)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibitory activity on human eosinophil phosphodiesterase 4.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7RH6PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50471668(CHEMBL309803)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibitory activity on human eosinophil phosphodiesterase 4.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7RH6PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of release of LTE4 in human whole bloodMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of release of LTE4 in human whole bloodMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50471677(CHEMBL76066)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibitory activity on human eosinophil phosphodiesterase 4.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7RH6PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50471683(CHEMBL74597)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibitory activity on human eosinophil phosphodiesterase 4.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7RH6PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50470781(CHEMBL281781)copy SMILEScopy InChI
Affinity DataIC50: 81nMAssay Description:Inhibition of Phosphodiesterase 4More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P12Q4PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM50176377((R)-2-(4-fluorophenoxy)-N-(1-(thiophen-2-yl)ethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 107nMAssay Description:Inhibition of PDE4AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348JXPPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50470788(CHEMBL278386)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of Phosphodiesterase 4More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P12Q4PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Mus musculus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50470778(CHEMBL21839)copy SMILEScopy InChI
Affinity DataIC50: 111nMAssay Description:Displacement of [3H]rolipram from mouse brain homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P12Q4PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Mus musculus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50470780(CHEMBL21305)copy SMILEScopy InChI
Affinity DataIC50: 129nMAssay Description:Displacement of [3H]rolipram from mouse brain homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P12Q4PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50470784(CHEMBL282934)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of Phosphodiesterase 4More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P12Q4PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Mus musculus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50470783(CHEMBL21327)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Displacement of [3H]rolipram from mouse brain homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P12Q4PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50470780(CHEMBL21305)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of Phosphodiesterase 4More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P12Q4PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50470778(CHEMBL21839)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of Phosphodiesterase 4More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P12Q4PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50471680(CHEMBL75247)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibitory activity on human eosinophil phosphodiesterase 4.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7RH6PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50471664(CHEMBL307286)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibitory activity on human eosinophil phosphodiesterase 4.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7RH6PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50470782(CHEMBL280185)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of Phosphodiesterase 4More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P12Q4PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50471666(CHEMBL308784)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibitory activity on human eosinophil phosphodiesterase 4.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7RH6PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346088((1r,4r)-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphe...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibitory activity on human eosinophil phosphodiesterase 4.More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM50176377((R)-2-(4-fluorophenoxy)-N-(1-(thiophen-2-yl)ethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 185nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348JXPPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50471672(CHEMBL75722)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibitory activity on human eosinophil phosphodiesterase 4.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7RH6PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50470785(CHEMBL422219)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of Phosphodiesterase 4More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P12Q4PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Mus musculus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50470785(CHEMBL422219)copy SMILEScopy InChI
Affinity DataIC50: 323nMAssay Description:Displacement of [3H]rolipram from mouse brain homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P12Q4PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50470787(CHEMBL22461)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Inhibition of Phosphodiesterase 4More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P12Q4PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50471669(CHEMBL305806)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Inhibitory activity on human eosinophil phosphodiesterase 4.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7RH6PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50471682(CHEMBL75819 | CP-220629)copy SMILEScopy InChI
Affinity DataIC50: 440nMAssay Description:Inhibitory activity on human eosinophil phosphodiesterase 4.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7RH6PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50471667(CHEMBL76065)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Inhibitory activity on human eosinophil phosphodiesterase 4.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7RH6PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50471662(CHEMBL406941)copy SMILEScopy InChI
Affinity DataIC50: 490nMAssay Description:Inhibitory activity on human eosinophil phosphodiesterase 4.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7RH6PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50470786(CHEMBL21964)copy SMILEScopy InChI
Affinity DataIC50: 520nMAssay Description:Inhibition of Phosphodiesterase 4More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P12Q4PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer, Inc.

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 625nMAssay Description:Inhibition of release of TNF alpha in human whole bloodMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Mus musculus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50470776(CHEMBL280729)copy SMILEScopy InChI
Affinity DataIC50: 653nMAssay Description:Displacement of [3H]rolipram from mouse brain homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P12Q4PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50471673(CHEMBL310509)copy SMILEScopy InChI
Affinity DataIC50: 660nMAssay Description:Inhibitory activity on human eosinophil phosphodiesterase 4.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7RH6PubMed
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