Affinity DataKi: 430nMAssay Description:Displacement of [3H]nisoxetine from recombinant human Dopamine transporter after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]nisoxetine from recombinant human Dopamine transporter after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]nisoxetine from recombinant human Dopamine transporter after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]nisoxetine from recombinant human Dopamine transporter after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]nisoxetine from recombinant human Dopamine transporter after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 347nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 570nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 759nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 760nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.18E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.18E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.23E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.31E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.32E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.32E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.32E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.45E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.55E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.58E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.62E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 2.04E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 2.08E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Displacement of [3H]nisoxetine from recombinant human Dopamine transporter after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 2.24E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 2.39E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 2.82E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Displacement of [3H]nisoxetine from recombinant human Dopamine transporter after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 3.09E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 3.10E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:Displacement of [3H]-Pentazocine from human recombinant sigma 1 receptor incubated for 120 mins by scintillation counting analysis relative to contro...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 3.53E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Displacement of [3H]nisoxetine from recombinant human Dopamine transporter after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 4.38E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 5.86E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 5.89E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 5.90E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 7.63E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 7.90E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 7.94E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine
Curated by ChEMBL
Vanderbilt University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair