Compile Data Set for Download or QSAR
Found 469 with Last Name = 'yevich' and Initial = 'jp'
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM14754(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)copy SMILEScopy InChI
Affinity DataKi:  8.00E+3nMAssay Description:Inhibition of rat lung cAMP-phosphodiesteraseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B917NPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50221806(CHEMBL18267)copy SMILEScopy InChI
Affinity DataKi:  7.00E+4nMAssay Description:Inhibition of rat lung cAMP-phosphodiesteraseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B917NPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM10847(1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dion...)copy SMILEScopy InChI
Affinity DataKi:  5.23E+5nMAssay Description:Inhibition of rat lung cAMP-phosphodiesteraseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B917NPubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50007692(8-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Binding affinity against rat 5-hydroxytryptamine 2 receptor in rat cerebral cortex tissue using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93VXPubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50007692(8-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor measured using radioligand ([3H]spiperone) binding assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24X58C9PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Bristol-Myers Company

Curated by ChEMBL
LigandPNGBDBM50016966(1,1-Dioxo-2-[4-(4-thieno[3,2-c]pyridin-4-yl-pipera...)copy SMILEScopy InChI
Affinity DataIC50: 0.680nMAssay Description:Ability to bind at serotonin 5-hydroxytryptamine 1A receptors of rat hippocampus by displacing [3H]8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HD7W8DPubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Bristol-Myers Company

Curated by ChEMBL
LigandPNGBDBM50016963(2-[4-(4-Thieno[3,2-c]pyridin-4-yl-piperazin-1-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 0.690nMAssay Description:Ability to bind at alpha-1 adrenergic receptor by displacing [3H]WB-4101More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HD7W8DPubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Bristol-Myers Company

Curated by ChEMBL
LigandPNGBDBM50007693(8-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)copy SMILEScopy InChI
Affinity DataIC50: 0.876nMAssay Description:Binding affinity against alpha-1 adrenergic receptor in rat cerebral cortex tissue using [3H]WB-4101 as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93VXPubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Bristol-Myers Company

Curated by ChEMBL
LigandPNGBDBM50367315(CHEMBL1203220)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:In vitro affinity for cortical alpha-1 adrenergic receptor labelled with [3H]WB-4101More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24X58C9PubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50282958(1-Cyclohexyl-4-[4-(5-fluoro-pyrimidin-2-yl)-pipera...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor by the displacement of [3H]-spiperone from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W6R
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Bristol-Myers Company

Curated by ChEMBL
LigandPNGBDBM50019378(3-[4-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-buty...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:In vitro affinity for cortical alpha-1 adrenergic receptor labelled with [3H]WB-4101More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24X58C9PubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Bristol-Myers Company

Curated by ChEMBL
LigandPNGBDBM50282974(CHEMBL58283 | N-{1-Cyclohexyl-4-[4-(5-fluoro-pyrim...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:In vitro binding affinity towards serotonin 5-HT1A receptor by the displacement of [3H]-8-OH-DPAT from rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W6R
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282973(4-Fluoro-N-{1-(4-fluoro-naphthalen-1-yl)-4-[4-(5-f...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:In vitro binding affinity of the compound towards sigma receptor by the displacement of [3H]-PPP from guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W6R
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50282962(1-(4-Fluoro-naphthalen-1-yl)-4-[4-(5-fluoro-pyrimi...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor by the displacement of [3H]-spiperone from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W6R
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Bristol-Myers Company

Curated by ChEMBL
LigandPNGBDBM50282966(CHEMBL58282 | N-{1-Cyclohexyl-4-[4-(5-fluoro-pyrim...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:In vitro binding affinity towards serotonin 5-HT1A receptor by the displacement of [3H]-8-OH-DPAT from rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W6R
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Bristol-Myers Company

Curated by ChEMBL
LigandPNGBDBM50016955(4-[4-(4-Thieno[3,2-c]pyridin-4-yl-piperazin-1-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Ability to bind at alpha-1 adrenergic receptor by displacing [3H]WB-4101More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HD7W8DPubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50007690(8-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Binding affinity against rat 5-hydroxytryptamine 2 receptor in rat cerebral cortex tissue using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93VXPubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Bristol-Myers Company

Curated by ChEMBL
LigandPNGBDBM50016966(1,1-Dioxo-2-[4-(4-thieno[3,2-c]pyridin-4-yl-pipera...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Ability to bind at alpha-1 adrenergic receptor by displacing [3H]WB-4101More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HD7W8DPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Bristol-Myers Company

Curated by ChEMBL
LigandPNGBDBM50016955(4-[4-(4-Thieno[3,2-c]pyridin-4-yl-piperazin-1-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Ability to bind at serotonin 5-hydroxytryptamine 1A receptors of rat hippocampus by displacing [3H]8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HD7W8DPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Bristol-Myers Company

Curated by ChEMBL
LigandPNGBDBM50016959(4-Methyl-1-[4-(4-thieno[3,2-c]pyridin-4-yl-piperaz...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Ability to bind at serotonin 5-hydroxytryptamine 1A receptors of rat hippocampus by displacing [3H]8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HD7W8DPubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Bristol-Myers Company

Curated by ChEMBL
LigandPNGBDBM50007694(8-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Binding affinity against alpha-1 adrenergic receptor in rat cerebral cortex tissue using [3H]WB-4101 as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93VXPubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Bristol-Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Compound was tested in vitro for its ability to displace radioligand (+)-[3H]-3-PPP from rat cortical sigma receptorMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Bristol-Myers Company

Curated by ChEMBL
LigandPNGBDBM50007690(8-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Binding affinity against alpha-1 adrenergic receptor in rat cerebral cortex tissue using [3H]WB-4101 as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93VXPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282974(CHEMBL58283 | N-{1-Cyclohexyl-4-[4-(5-fluoro-pyrim...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:In vitro binding affinity of the compound towards sigma receptor by the displacement of [3H]-PPP from guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W6R
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50008735((+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of [3H]spiperone binding to dopamine receptor from rat corpus striatal membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73GXDPubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Bristol-Myers Company

Curated by ChEMBL
LigandPNGBDBM50019359(4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-1-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:In vitro affinity for cortical alpha-1 adrenergic receptor labelled with [3H]WB-4101More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24X58C9PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50019359(4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-1-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:In vitro affinity for rat striatal Dopamine receptor D2 labeled with [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24X58C9PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Bristol-Myers Company

Curated by ChEMBL
LigandPNGBDBM50019376(4-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-1-(4-fl...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:In vitro affinity for cortical alpha-1 adrenergic receptor labelled with [3H]WB-4101More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24X58C9PubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50007693(8-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Binding affinity against rat 5-hydroxytryptamine 2 receptor in rat cerebral cortex tissue using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93VXPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Bristol-Myers Company

Curated by ChEMBL
LigandPNGBDBM50016971(3-{4-[4-(2-Methyl-furo[3,2-c]pyridin-4-yl)-piperaz...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Ability to bind at 5-hydroxytryptamine 1A receptor of rat hippocampus by displacing [3H]8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HD7W8DPubMed
Target5-hydroxytryptamine receptor 1A/1B/1D/1F(RAT)
Bristol-Myers Company

Curated by ChEMBL
LigandPNGBDBM50016966(1,1-Dioxo-2-[4-(4-thieno[3,2-c]pyridin-4-yl-pipera...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Ability to bind at 5-hydroxytryptamine 1 receptor of rat hippocampus by displacing [3H]5-HTMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HD7W8DPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Bristol-Myers Company

Curated by ChEMBL
LigandPNGBDBM50016969(1-[4-(4-Thieno[3,2-c]pyridin-4-yl-piperazin-1-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Ability to bind at serotonin 5-hydroxytryptamine 1A receptors of rat hippocampus by displacing [3H]8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HD7W8DPubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Bristol-Myers Company

Curated by ChEMBL
LigandPNGBDBM50007691(3-Oxo-2-oxa-spiro[4.4]nonane-1-carboxylic acid [4-...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Binding affinity against alpha-1 adrenergic receptor in rat cerebral cortex tissue using [3H]WB-4101 as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93VXPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Bristol-Myers Company

Curated by ChEMBL
LigandPNGBDBM50016963(2-[4-(4-Thieno[3,2-c]pyridin-4-yl-piperazin-1-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Ability to bind at serotonin 5-hydroxytryptamine 1A receptors of rat hippocampus by displacing [3H]8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HD7W8DPubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50016963(2-[4-(4-Thieno[3,2-c]pyridin-4-yl-piperazin-1-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Ability to bind at serotonin 5-hydroxytryptamine 2 receptors of rat hippocampus by displacing [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HD7W8DPubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50007694(8-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Binding affinity against rat 5-hydroxytryptamine 2 receptor in rat cerebral cortex tissue using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93VXPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Bristol-Myers Company

Curated by ChEMBL
LigandPNGBDBM50007692(8-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor of rat hippocampal tissue with [3H]-8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93VXPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Bristol-Myers Company

Curated by ChEMBL
LigandPNGBDBM50007694(8-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor using in rat hippocampal tissue using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93VXPubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Bristol-Myers Company

Curated by ChEMBL
LigandPNGBDBM50019372(8-[3-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-pr...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:In vitro affinity for cortical alpha-1 adrenergic receptor labelled with [3H]WB-4101More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24X58C9PubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50016960(4,4-Dimethyl-1-[4-(4-thieno[3,2-c]pyridin-4-yl-pip...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Ability to bind at serotonin 5-hydroxytryptamine 2 receptors of rat hippocampus by displacing [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HD7W8DPubMed
Target5-hydroxytryptamine receptor 1A/1B/1D/1F(RAT)
Bristol-Myers Company

Curated by ChEMBL
LigandPNGBDBM50016967(3-{4-[4-(2-Methyl-thieno[3,2-c]pyridin-4-yl)-piper...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Ability to bind at 5-hydroxytryptamine 1 receptor of rat hippocampus by displacing [3H]5-HTMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HD7W8DPubMed
Target5-hydroxytryptamine receptor 1A/1B/1D/1F(RAT)
Bristol-Myers Company

Curated by ChEMBL
LigandPNGBDBM50016957(3-[4-(4-Thieno[2,3-c]pyridin-7-yl-piperazin-1-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:In vitro evaluation for arachidonic acid induced platelet aggregation of human platelet-rich plasmaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HD7W8DPubMed
Target5-hydroxytryptamine receptor 1A/1B/1D/1F(RAT)
Bristol-Myers Company

Curated by ChEMBL
LigandPNGBDBM50016956(1-{4-[4-(2-Bromo-thieno[3,2-c]pyridin-4-yl)-pipera...)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Ability to bind at 5-hydroxytryptamine 1 receptor of rat hippocampus by displacing [3H]5-HTMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HD7W8DPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Bristol-Myers Company

Curated by ChEMBL
LigandPNGBDBM50007693(8-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor using in rat hippocampal tissue using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93VXPubMed
Target5-hydroxytryptamine receptor 1A/1B/1D/1F(RAT)
Bristol-Myers Company

Curated by ChEMBL
LigandPNGBDBM50016958(1-(4-Fluoro-phenyl)-4-(4-thieno[3,2-c]pyridin-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Ability to bind at 5-hydroxytryptamine 1 receptor of rat hippocampus by displacing [3H]5-HTMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HD7W8DPubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50016964(3-[4-(4-Thieno[3,2-c]pyridin-4-yl-piperazin-1-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Ability to bind at 5-hydroxytryptamine 2 receptor of rat hippocampus by displacing [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HD7W8DPubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Bristol-Myers Company

Curated by ChEMBL
LigandPNGBDBM50019368(1-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:In vitro affinity for cortical alpha-1 adrenergic receptor labelled with [3H]WB-4101More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24X58C9PubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50016959(4-Methyl-1-[4-(4-thieno[3,2-c]pyridin-4-yl-piperaz...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Ability to bind at serotonin 5-hydroxytryptamine 2 receptors of rat hippocampus by displacing [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HD7W8DPubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50007691(3-Oxo-2-oxa-spiro[4.4]nonane-1-carboxylic acid [4-...)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:Binding affinity against rat 5-hydroxytryptamine 2 receptor in rat cerebral cortex tissue using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93VXPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Bristol-Myers Company

Curated by ChEMBL
LigandPNGBDBM50016965(4,4-Dimethyl-1-{4-[4-(2-methyl-furo[3,2-c]pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMAssay Description:Ability to bind at serotonin 5-hydroxytryptamine 1A receptors of rat hippocampus by displacing [3H]8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HD7W8DPubMed
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