Compile Data Set for Download or QSAR
Found 39 with Last Name = 'guo' and Initial = 'jq'
TargetS-adenosylmethionine decarboxylase proenzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403124(CHEMBL2115571)copy SMILEScopy InChI
Affinity DataKi:  3.80E+3nMAssay Description:Compound was evaluated to inactivate the bacterial AdoMet-DC; value ranges from 3.8 to 39.6 uMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8N6T
TargetS-adenosylmethionine decarboxylase proenzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281293(2-amino-5-({[(2S,3S,4R)-5-(6-amino-9H-purin-9-yl)-...)copy SMILEScopy InChI
Affinity DataKi:  7.20E+3nMAssay Description:Compound was evaluated to inactivate the human AdoMet-DCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8N6T
TargetS-adenosylmethionine decarboxylase proenzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403124(CHEMBL2115571)copy SMILEScopy InChI
Affinity DataKi:  1.07E+4nMAssay Description:Compound was evaluated to inactivate the human AdoMet-DC; value ranges from 10.7 to 62.7 uMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8N6T
TargetS-adenosylmethionine decarboxylase proenzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403124(CHEMBL2115571)copy SMILEScopy InChI
Affinity DataKi:  1.07E+4nMAssay Description:Compound was evaluated to inactivate the bacterial AdoMet-DC; value ranges from 3.8 to 39.6 uMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8N6T
TargetS-adenosylmethionine decarboxylase proenzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366321(CHEMBL3392203 | CHEMBL606101)copy SMILEScopy InChI
Affinity DataKi:  1.80E+4nMAssay Description:Tested for irreversible inhibitory activity against AdoMet-DC (S-adenosyl-methionine decarboxylase-) isolated from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7WG3
TargetS-adenosylmethionine decarboxylase proenzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281292(2-amino-4-({[(2S,3S,4R)-5-(6-amino-9H-purin-9-yl)-...)copy SMILEScopy InChI
Affinity DataKi:  3.11E+4nMAssay Description:Compound was evaluated to inactivate the bacterial AdoMet-DCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8N6T
TargetS-adenosylmethionine decarboxylase proenzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281292(2-amino-4-({[(2S,3S,4R)-5-(6-amino-9H-purin-9-yl)-...)copy SMILEScopy InChI
Affinity DataKi:  2.47E+5nMAssay Description:Compound was evaluated to inactivate the human AdoMet-DCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8N6T
TargetS-adenosylmethionine decarboxylase proenzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366318(CHEMBL3392208 | CHEMBL605698)copy SMILEScopy InChI
Affinity DataKi:  4.15E+5nMAssay Description:Tested for irreversible inhibitory activity against AdoMet-DC (S-adenosyl-methionine decarboxylase-) isolated from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7WG3
TargetS-adenosylmethionine decarboxylase proenzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366320(CHEMBL3392206 | CHEMBL605899)copy SMILEScopy InChI
Affinity DataKi:  4.78E+5nMAssay Description:Tested for irreversible inhibitory activity against AdoMet-DC (S-adenosyl-methionine decarboxylase-) isolated from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7WG3
TargetS-adenosylmethionine decarboxylase proenzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366317(CHEMBL3392204 | CHEMBL606102)copy SMILEScopy InChI
Affinity DataKi:  6.69E+5nMAssay Description:Tested for irreversible inhibitory activity against AdoMet-DC (S-adenosyl-methionine decarboxylase-) isolated from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7WG3
TargetS-adenosylmethionine decarboxylase proenzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366316(CHEMBL3392209 | CHEMBL605267)copy SMILEScopy InChI
Affinity DataKi:  9.60E+5nMAssay Description:Tested for irreversible inhibitory activity against AdoMet-DC (S-adenosyl-methionine decarboxylase-) isolated from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7WG3
TargetS-adenosylmethionine decarboxylase proenzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366319(CHEMBL1791405 | CHEMBL3392205)copy SMILEScopy InChI
Affinity DataKi:  1.07E+6nMAssay Description:Tested for irreversible inhibitory activity against AdoMet-DC (S-adenosyl-methionine decarboxylase-) isolated from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7WG3
TargetS-adenosylmethionine decarboxylase proenzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366319(CHEMBL1791405 | CHEMBL3392205)copy SMILEScopy InChI
Affinity DataKi:  1.07E+6nMAssay Description:Tested for irreversible inhibitory activity against AdoMet-DC (S-adenosyl-methionine decarboxylase-) isolated from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7WG3
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience Inc.

Curated by ChEMBL
LigandPNGBDBM50344821(10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RF5PubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience Inc.

Curated by ChEMBL
LigandPNGBDBM50066062(1,3-Bis-(4-sec-butyl-phenyl)-imidazolidin-2-yliden...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RF5PubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience Inc.

Curated by ChEMBL
LigandPNGBDBM50066059(1,3-Bis-(4-sec-butyl-phenyl)-tetrahydro-pyrimidin-...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RF5PubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience Inc.

Curated by ChEMBL
LigandPNGBDBM50066066((S)-1-[4-(Benzothiazol-2-yl-methyl-amino)-piperidi...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RF5PubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience Inc.

Curated by ChEMBL
LigandPNGBDBM50066067(2-(4-tert-Butyl-phenyl)-6-isopropyl-3,4-dihydro-2H...)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RF5PubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience Inc.

Curated by ChEMBL
LigandPNGBDBM50066069(CHEMBL103284 | N-(4-tert-Butyl-benzyl)-N-(4-sec-bu...)copy SMILEScopy InChI
Affinity DataIC50: 620nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RF5PubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience Inc.

Curated by ChEMBL
LigandPNGBDBM50066052((3-sec-Butyl-phenyl)-[1-(4-sec-butyl-phenyl)-imida...)copy SMILEScopy InChI
Affinity DataIC50: 780nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RF5PubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience Inc.

Curated by ChEMBL
LigandPNGBDBM50066057(CHEMBL110909 | CHEMBL320199 | N,N'-Bis-(4-sec-buty...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RF5PubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience Inc.

Curated by ChEMBL
LigandPNGBDBM50066060(CHEMBL545504 | N,N'-Bis-(4-sec-butyl-phenyl)-N,N'-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RF5PubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience Inc.

Curated by ChEMBL
LigandPNGBDBM50066068(CHEMBL28853 | N-Acenaphthen-5-yl-N'-(4-methoxy-nap...)copy SMILEScopy InChI
Affinity DataIC50: 1.64E+3nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RF5PubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience Inc.

Curated by ChEMBL
LigandPNGBDBM50066061(1-(4-sec-Butyl-phenyl)-5-(4-isopropyl-phenyl)-imid...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RF5PubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience Inc.

Curated by ChEMBL
LigandPNGBDBM50066063(9,15-Dioxa-2,4-diaza-tricyclo[14.2.2.2*5,8*]docosa...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RF5PubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience Inc.

Curated by ChEMBL
LigandPNGBDBM50066053(CHEMBL544569 | N,N'-Bis-(4-ethoxy-phenyl)-guanidin...)copy SMILEScopy InChI
Affinity DataIC50: 3.28E+3nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RF5PubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281292(2-amino-4-({[(2S,3S,4R)-5-(6-amino-9H-purin-9-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Compound was evaluated for its inhibitory activity against AdoMet-DC from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8N6T
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience Inc.

Curated by ChEMBL
LigandPNGBDBM50066055(3-Phenyl-1,2,3,4-tetrahydro-quinazolin-2-ylamine; ...)copy SMILEScopy InChI
Affinity DataIC50: 9.95E+3nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RF5PubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience Inc.

Curated by ChEMBL
LigandPNGBDBM50010769(CHEMBL556117 | CHEMBL77675 | N,N'-Diphenyl-guanidi...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RF5PubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience Inc.

Curated by ChEMBL
LigandPNGBDBM50010804(1,3-Diphenyl-imidazolidin-2-ylideneamine | CHEMBL5...)copy SMILEScopy InChI
Affinity DataIC50: 1.47E+4nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RF5PubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience Inc.

Curated by ChEMBL
LigandPNGBDBM50066070(2-Phenyl-3,4-dihydro-2H-quinoline-1-carboxamidine;...)copy SMILEScopy InChI
Affinity DataIC50: 1.76E+4nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RF5PubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience Inc.

Curated by ChEMBL
LigandPNGBDBM50066056(1,5-Diphenyl-imidazolidin-(2Z)-ylideneamine; hydro...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+4nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RF5PubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience Inc.

Curated by ChEMBL
LigandPNGBDBM50066064(CHEMBL103505 | Phenyl-[1-phenyl-imidazolidin-(2E)-...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RF5PubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience Inc.

Curated by ChEMBL
LigandPNGBDBM50066065(1,3-Diphenyl-tetrahydro-pyrimidin-2-ylideneamine; ...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RF5PubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience Inc.

Curated by ChEMBL
LigandPNGBDBM50066054(11,12-Dihydro-6H-dibenzo[b,f]azocine-5-carboxamidi...)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+4nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RF5PubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281293(2-amino-5-({[(2S,3S,4R)-5-(6-amino-9H-purin-9-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Compound was evaluated to inactivate the bacterial AdoMet-DCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8N6T
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience Inc.

Curated by ChEMBL
LigandPNGBDBM50066071(CHEMBL543152 | N-Benzyl-N-phenyl-guanidine; hydroc...)copy SMILEScopy InChI
Affinity DataIC50: 5.30E+4nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RF5PubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366314(CHEMBL3392211 | CHEMBL607699)copy SMILEScopy InChI
Affinity DataIC50: 1.79E+5nMAssay Description:Compound was evaluated for its inhibitory activity against AdoMet-DC from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8N6T
TargetS-adenosylmethionine decarboxylase proenzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366315(CHEMBL1163096 | CHEMBL3392218)copy SMILEScopy InChI
Affinity DataIC50: 2.05E+5nMAssay Description:Compound was evaluated for its inhibitory activity against AdoMet-DC from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8N6T