Compile Data Set for Download or QSAR
Found 50 with Last Name = 'clayton' and Initial = 'jr'
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063687(CHEMBL3397339)copy SMILEScopy InChI
Affinity DataKi:  0.0400nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063689(CHEMBL3397337)copy SMILEScopy InChI
Affinity DataKi:  0.0700nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063755(CHEMBL3397341)copy SMILEScopy InChI
Affinity DataKi:  0.0900nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063688(CHEMBL3397338)copy SMILEScopy InChI
Affinity DataKi:  0.140nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063686(CHEMBL3397340)copy SMILEScopy InChI
Affinity DataKi:  0.180nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063690(CHEMBL3397336)copy SMILEScopy InChI
Affinity DataKi:  0.260nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063754(CHEMBL3397342)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063689(CHEMBL3397337)copy SMILEScopy InChI
Affinity DataKi:  0.350nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063687(CHEMBL3397339)copy SMILEScopy InChI
Affinity DataKi:  0.380nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063691(CHEMBL3397335)copy SMILEScopy InChI
Affinity DataKi:  0.380nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063755(CHEMBL3397341)copy SMILEScopy InChI
Affinity DataKi:  0.510nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063752(CHEMBL3397343)copy SMILEScopy InChI
Affinity DataKi:  0.540nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063751(CHEMBL3397344)copy SMILEScopy InChI
Affinity DataKi:  0.640nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063693(CHEMBL3397333)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063750(CHEMBL3397345)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063690(CHEMBL3397336)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063692(CHEMBL3397334)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063688(CHEMBL3397338)copy SMILEScopy InChI
Affinity DataKi:  2.10nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063686(CHEMBL3397340)copy SMILEScopy InChI
Affinity DataKi:  2.80nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063695(CHEMBL3397346)copy SMILEScopy InChI
Affinity DataKi:  3.10nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063691(CHEMBL3397335)copy SMILEScopy InChI
Affinity DataKi:  7.70nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063694(CHEMBL3397347)copy SMILEScopy InChI
Affinity DataKi:  8nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRbeta expressed in human Hela cell lysate measured after overnight incubation by competi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063754(CHEMBL3397342)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063693(CHEMBL3397333)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063692(CHEMBL3397334)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063751(CHEMBL3397344)copy SMILEScopy InChI
Affinity DataKi:  32nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063752(CHEMBL3397343)copy SMILEScopy InChI
Affinity DataKi:  37nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063750(CHEMBL3397345)copy SMILEScopy InChI
Affinity DataKi:  47nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063695(CHEMBL3397346)copy SMILEScopy InChI
Affinity DataKi:  90nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063694(CHEMBL3397347)copy SMILEScopy InChI
Affinity DataKi:  200nMAssay Description:Displacement of [125I]-L-3,5,3'-triiodothyronine from human TRalpha expressed in human Hela cell lysate measured after overnight incubation by compet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398506((2R)-1,1,1-Trifluoro-3-({cis-4-[(1-methyl-4-{[1-(p...)copy SMILEScopy InChI
Affinity DataIC50: 1.49nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398504((2R)-1,1,1-Trifluoro-3-[(cis-1-methyl-4-{[1-methyl...)copy SMILES
Affinity DataIC50: 1.91nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398501((2R)-1,1,1-Trifluoro-3-({cis-4-[(4-{[1-(3-methoxyp...)copy SMILEScopy InChI
Affinity DataIC50: 3.25nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398502((2R)-1,1,1-Trifluoro-3-{[cis-4-({4-[(5-methoxy-1-m...)copy SMILEScopy InChI
Affinity DataIC50: 5.25nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398505((2R)-3-{[cis-4-({4-[(1,5-Dimethyl-1H-pyrazol-3-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 5.35nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398503((2R)-3-{[(cis-4-({4-[(Ethyl-5-methyl-1H-pyrazol-3-...)copy SMILEScopy InChI
Affinity DataIC50: 5.43nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398506((2R)-1,1,1-Trifluoro-3-({cis-4-[(1-methyl-4-{[1-(p...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398504((2R)-1,1,1-Trifluoro-3-[(cis-1-methyl-4-{[1-methyl...)copy SMILES
Affinity DataIC50: 239nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398506((2R)-1,1,1-Trifluoro-3-({cis-4-[(1-methyl-4-{[1-(p...)copy SMILEScopy InChI
Affinity DataIC50: 660nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398505((2R)-3-{[cis-4-({4-[(1,5-Dimethyl-1H-pyrazol-3-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 767nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398502((2R)-1,1,1-Trifluoro-3-{[cis-4-({4-[(5-methoxy-1-m...)copy SMILEScopy InChI
Affinity DataIC50: 768nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398503((2R)-3-{[(cis-4-({4-[(Ethyl-5-methyl-1H-pyrazol-3-...)copy SMILEScopy InChI
Affinity DataIC50: 901nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398504((2R)-1,1,1-Trifluoro-3-[(cis-1-methyl-4-{[1-methyl...)copy SMILES
Affinity DataIC50: 1.17E+3nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398501((2R)-1,1,1-Trifluoro-3-({cis-4-[(4-{[1-(3-methoxyp...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398505((2R)-3-{[cis-4-({4-[(1,5-Dimethyl-1H-pyrazol-3-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.14E+3nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398502((2R)-1,1,1-Trifluoro-3-{[cis-4-({4-[(5-methoxy-1-m...)copy SMILEScopy InChI
Affinity DataIC50: 2.54E+3nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398501((2R)-1,1,1-Trifluoro-3-({cis-4-[(4-{[1-(3-methoxyp...)copy SMILEScopy InChI
Affinity DataIC50: 3.72E+3nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM398503((2R)-3-{[(cis-4-({4-[(Ethyl-5-methyl-1H-pyrazol-3-...)copy SMILEScopy InChI
Affinity DataIC50: 6.16E+3nMAssay Description:The JAK LanthaScreen Kinase Assay (Invitrogen) is used to determine the ability of test compounds to inhibit JAK1, JAK2, and JAK3 kinase activity. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TF00QZUS Patent
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063752(CHEMBL3397343)copy SMILEScopy InChI
Affinity DataEC50:  2.47E+3nMAssay Description:Agonist activity at TRalpha (unknown origin) expressed in human HuH7 cells after 24 hrs by Gal4 CTF cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063752(CHEMBL3397343)copy SMILEScopy InChI
Affinity DataEC50:  406nMAssay Description:Agonist activity at TRbeta (unknown origin) expressed in human HuH7 cells after 24 hrs by Gal4 CTF cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N2GPubMed