Compile Data Set for Download or QSAR
Found 111 with Last Name = 'koehl' and Initial = 'jr'
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50044868(7-(1-Carboxy-3-phenyl-propylamino)-6-oxo-1,2,3,4,6...)copy SMILEScopy InChI
Affinity DataKi:  0.00400nMAssay Description:Binding affinity of compound against rabbit lung angiotensin I-converting enzyme (ACE) was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22N51C1PubMed
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50175518((3R,7S)-7-((R)-2-Mercapto-3-phenyl-propionylamino)...)copy SMILEScopy InChI
Affinity DataKi:  0.0700nMAssay Description:Compound was tested for inhibition of neutral endopeptidase (NEP).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7GMV
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50044866(7-(2-Mercapto-3-phenyl-propionylamino)-6-oxo-1,2,3...)copy SMILEScopy InChI
Affinity DataKi:  0.0800nMAssay Description:Binding affinity of compound against rat kidney neutral endopeptidase (NEP) was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22N51C1PubMed
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50044866(7-(2-Mercapto-3-phenyl-propionylamino)-6-oxo-1,2,3...)copy SMILEScopy InChI
Affinity DataKi:  0.0800nMAssay Description:Binding affinity of compound against rat kidney neutral endopeptidase (NEP) was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22N51C1PubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50044866(7-(2-Mercapto-3-phenyl-propionylamino)-6-oxo-1,2,3...)copy SMILEScopy InChI
Affinity DataKi:  0.110nMAssay Description:Binding affinity of compound against rabbit lung angiotensin I-converting enzyme (ACE) was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22N51C1PubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50044866(7-(2-Mercapto-3-phenyl-propionylamino)-6-oxo-1,2,3...)copy SMILEScopy InChI
Affinity DataKi:  0.110nMAssay Description:Binding affinity of compound against rabbit lung angiotensin I-converting enzyme (ACE) was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22N51C1PubMed
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50287694(3-[(2-Mercaptomethyl-1,2,3,4-tetrahydro-naphthalen...)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MSW
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50287702((S)-2-[(2-Mercaptomethyl-1,2,3,4-tetrahydro-naphth...)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MSW
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50287689(CHEMBL304233 | [(2-Mercaptomethyl-1,2,3,4-tetrahyd...)copy SMILEScopy InChI
Affinity DataKi:  0.400nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MSW
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50289194((S)-2-[(S)-4-((R)-2-Mercapto-3-phenyl-propionylami...)copy SMILEScopy InChI
Affinity DataKi:  0.400nMAssay Description:Compound was tested for inhibition of neutral endopeptidase (NEP).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7GMV
TargetNeutrophil elastase(Homo sapiens (Human))
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50035500((S)-1-{(S)-2-[4-(4-Chloro-benzenesulfonylaminocarb...)copy SMILEScopy InChI
Affinity DataKi:  0.5nMAssay Description:Binding affinity of the compound for purified Human neutrophil elastase was determined in vitro.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC0ZPCPubMed
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50287700((S)-3-(4-Hydroxy-phenyl)-2-[(2-mercaptomethyl-1,2,...)copy SMILEScopy InChI
Affinity DataKi:  0.5nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MSW
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50287690(7-[(2-Mercaptomethyl-1,2,3,4-tetrahydro-naphthalen...)copy SMILEScopy InChI
Affinity DataKi:  0.600nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MSW
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50287699(4-[(2-Mercaptomethyl-1,2,3,4-tetrahydro-naphthalen...)copy SMILEScopy InChI
Affinity DataKi:  0.600nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MSW
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50024096(((R)-2-Mercaptomethyl-3-phenyl-propionylamino)-ace...)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MSW
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50024102(((S)-2-Mercaptomethyl-3-phenyl-propionylamino)-ace...)copy SMILEScopy InChI
Affinity DataKi:  1.90nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50024096(((R)-2-Mercaptomethyl-3-phenyl-propionylamino)-ace...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Binding affinity of compound against rat kidney neutral endopeptidase (NEP) was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22N51C1PubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50035489((S)-1-{(S)-3-Methyl-2-[4-(morpholine-4-sulfonyl)-b...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:In vitro inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P615XPubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50044867(7-Mercaptomethyl-6-oxo-1,2,3,4,6,7,8,12b-octahydro...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Binding affinity of compound against rat kidney neutral endopeptidase (NEP) was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22N51C1PubMed
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50287696((S)-2-[(2-Mercaptomethyl-1,2,3,4-tetrahydro-naphth...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MSW
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50044869(7-(2-Mercapto-acetylamino)-6-oxo-1,2,3,4,6,7,8,12b...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Binding affinity of compound against rabbit lung angiotensin I-converting enzyme (ACE) was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22N51C1PubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50069667((S)-3-{[1-((S)-2-{(S)-2-[4-(4-Chloro-benzenesulfon...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Tested for rate of substrate hydrolysis in the presence of human neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936PKPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50035528(Acetic acid (E)-2-[((S)-1-{(S)-2-[4-(4-chloro-benz...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Binding affinity of the compound for purified Human neutrophil elastase was determined in the presence of pig liver esterase, in vitro.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC0ZPCPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50035500((S)-1-{(S)-2-[4-(4-Chloro-benzenesulfonylaminocarb...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:In vitro inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P615XPubMed
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50287695((S)-2-[(2-Mercaptomethyl-1,2,3,4-tetrahydro-naphth...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MSW
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50287701((4S,7S)-7-(2-Mercapto-acetylamino)-6-oxo-1,2,3,4,6...)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MSW
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50044869(7-(2-Mercapto-acetylamino)-6-oxo-1,2,3,4,6,7,8,12b...)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Binding affinity of compound against rat kidney neutral endopeptidase (NEP) was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22N51C1PubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50044867(7-Mercaptomethyl-6-oxo-1,2,3,4,6,7,8,12b-octahydro...)copy SMILEScopy InChI
Affinity DataKi: >7nMAssay Description:Binding affinity of compound against rabbit lung angiotensin I-converting enzyme (ACE) was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22N51C1PubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50035488((S)-1-{(S)-2-[4-(4-Chloro-benzenesulfonylaminocarb...)copy SMILEScopy InChI
Affinity DataKi:  7nMAssay Description:In vitro inhibitory activity against human neutrophil elastase was determined at a dose of 100 mg/kgMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P615XPubMed
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50287693((S)-2-[(2-Mercaptomethyl-1,2,3,4-tetrahydro-naphth...)copy SMILEScopy InChI
Affinity DataKi:  7nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MSW
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Hoechst Marion Roussel, Inc.

Curated by ChEMBL
LigandPNGBDBM50073850((S)-2-((S)-2-Benzyloxycarbonylamino-3-methyl-butyr...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Tested for inhibitory activity against calpain.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F1907JPubMed
TargetCalpain-1 catalytic subunit(Gallus gallus)
Hoechst Marion Roussel, Inc.

Curated by ChEMBL
LigandPNGBDBM50073850((S)-2-((S)-2-Benzyloxycarbonylamino-3-methyl-butyr...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Inhibitory activity against chicken gizzard smooth muscle calpainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN4476PubMed
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50287692(CHEMBL431957 | [(2-Mercaptomethyl-indane-2-carbony...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MSW
TargetNeutrophil elastase(Homo sapiens (Human))
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50035498((S)-1-{(S)-3-Methyl-2-[4-(morpholine-4-carbonyl)-b...)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Binding affinity of the compound for purified Human neutrophil elastase was determined in vitro.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC0ZPCPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50035498((S)-1-{(S)-3-Methyl-2-[4-(morpholine-4-carbonyl)-b...)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:In vitro inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P615XPubMed
TargetS-formylglutathione hydrolase(Sus scrofa)
Cinc

Curated by ChEMBL
LigandPNGBDBM50069665((E)-2-Acetoxy-3-{[(S)-1-((S)-2-{(S)-2-[4-(4-chloro...)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Tested for inhibition of substrate hydrolysis in the presence of porcine kidney esterase at a concentration of 10 nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936PKPubMed
TargetS-formylglutathione hydrolase(Sus scrofa)
Cinc

Curated by ChEMBL
LigandPNGBDBM50069665((E)-2-Acetoxy-3-{[(S)-1-((S)-2-{(S)-2-[4-(4-chloro...)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:pA2 value towards endothelin receptor A was determined as functional ETA antagonismMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936PKPubMed
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50287691(2-Mercaptomethyl-1,2,3,4-tetrahydro-naphthalene-2-...)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5MSW
TargetNeutrophil elastase(Homo sapiens (Human))
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50035535(Acetic acid (E)-3-methyl-2-[((S)-1-{(S)-3-methyl-2...)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Binding affinity of the compound for purified Human neutrophil elastase was determined in the presence of pig liver esterase, in vitro.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC0ZPCPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50065147((S)-1-{(S)-3-Methyl-2-[4-(morpholine-4-carbonyl)-b...)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Inhibition of human neutrophil elastase in hamster lungs following 25 mg/kg pre-treatment before instillation of elastase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X85S8PubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50035492((S)-1-{(S)-3-Methyl-2-[4-(2-methyl-4-morpholin-4-y...)copy SMILEScopy InChI
Affinity DataKi:  19nMAssay Description:In vitro inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P615XPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50035495((S)-1-{(S)-3-Methyl-2-[4-(morpholine-4-carbonyl)-b...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Inhibition of human neutrophil elastase in hamster lungs following 25 mg/kg pre-treatment before instillation of elastase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X85S8PubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50065158((R)-4-Benzyloxy-1-{(S)-3-methyl-2-[4-(morpholine-4...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Inhibition of human neutrophil elastase in hamster lungs following 25 mg/kg pre-treatment before instillation of elastase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X85S8PubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50035494(CHEMBL429359 | N-{(S)-2-Methyl-1-[(S)-2-(3,3,4,4,4...)copy SMILEScopy InChI
Affinity DataKi:  21nMAssay Description:In vitro inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P615XPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50035485((S)-1-((S)-3-Methyl-2-{4-[4-(morpholine-4-carbonyl...)copy SMILEScopy InChI
Affinity DataKi:  24nMAssay Description:In vitro inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P615XPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50035495((S)-1-{(S)-3-Methyl-2-[4-(morpholine-4-carbonyl)-b...)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:Binding affinity of the compound for purified Human neutrophil elastase was determined in vitro.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC0ZPCPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50035530(CHEMBL74651 | Propionic acid (E)-3-methyl-2-[((S)-...)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:Binding affinity of the compound for purified Human neutrophil elastase was determined in the presence of pig liver esterase, in vitro.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC0ZPCPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50035531(CHEMBL74332 | Isobutyric acid (E)-3-methyl-2-[((S)...)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:Binding affinity of the compound for purified Human neutrophil elastase was determined in the presence of pig liver esterase, in vitro.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC0ZPCPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50035495((S)-1-{(S)-3-Methyl-2-[4-(morpholine-4-carbonyl)-b...)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:In vitro inhibitory activity against human neutrophil elastase was determined at a dose of 50 mg/kgMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P615XPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50035532(Acetic acid (E)-3-methyl-2-[((S)-1-{(S)-3-methyl-2...)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:Binding affinity of the compound for purified Human neutrophil elastase was determined in the presence of pig liver esterase, in vitro.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC0ZPCPubMed
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