Compile Data Set for Download or QSAR
Found 453 with Last Name = 'marszalek' and Initial = 'jr'
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
MD Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50152127(CHEMBL3780962)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2BF6PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
MD Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50152144(CHEMBL3781661)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2BF6PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
MD Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50152129(CHEMBL3780596)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2BF6PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
MD Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50152130(CHEMBL3780613)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2BF6PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM506627(US11046649, Ex. 5)copy SMILES
Affinity DataIC50: 0.520nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P9SPubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
MD Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50152145(CHEMBL3780032)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2BF6PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50578624(CHEMBL4856710)copy SMILES
Affinity DataIC50: 0.600nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P9SPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50578623(CHEMBL4858888)copy SMILES
Affinity DataIC50: 0.690nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P9SPubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
MD Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50152125(CHEMBL3781316)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of recombinant human MTH1 assessed as hydrolysis of dGTP to dGMP and pyrophosphate after 15 mins by malachite green-based microplate reade...More data for this Ligand-Target Pair
LigandPNGBDBM50560806(CHEMBL4758092)copy SMILES
Affinity DataIC50: 0.800nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50578677(CHEMBL4849690)copy SMILES
Affinity DataIC50: 0.920nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P9SPubMed
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)TBA
LigandPNGBDBM50578623(CHEMBL4858888)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of IDO1 in mouse Panc02 cells assessed as reduction in NFK level incubated for 48 hrs by RFMS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P9SPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50578635(CHEMBL4875089)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P9SPubMed
LigandPNGBDBM50560807(CHEMBL4751287)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50560804(CHEMBL4763875)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50460035(CHEMBL4227505)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of CSF1R (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50560786(CHEMBL4798876)copy SMILES
Affinity DataIC50: 1.10nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50560798(CHEMBL4795462)copy SMILES
Affinity DataIC50: 1.10nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50560801(CHEMBL4798601)copy SMILES
Affinity DataIC50: 1.20nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50560791(CHEMBL4740157)copy SMILES
Affinity DataIC50: 1.20nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50578639(CHEMBL4868112)copy SMILES
Affinity DataIC50: 1.40nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P9SPubMed
LigandPNGBDBM50560788(CHEMBL4759047)copy SMILES
Affinity DataIC50: 1.40nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
MD Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50152125(CHEMBL3781316)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50578633(CHEMBL4872522)copy SMILES
Affinity DataIC50: 1.60nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P9SPubMed
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)TBA
LigandPNGBDBM50578625(CHEMBL4855340)copy SMILES
Affinity DataIC50: 1.60nMAssay Description:Inhibition of IDO1 in mouse Panc02 cells assessed as reduction in NFK level incubated for 48 hrs by RFMS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P9SPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50578622(CHEMBL4861332)copy SMILES
Affinity DataIC50: 1.70nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P9SPubMed
LigandPNGBDBM50560812(CHEMBL4748740)copy SMILES
Affinity DataIC50: 1.70nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
MD Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50152126(CHEMBL3780321)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2BF6PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)TBA
LigandPNGBDBM50578624(CHEMBL4856710)copy SMILES
Affinity DataIC50: 2nMAssay Description:Inhibition of IDO1 in mouse Panc02 cells assessed as reduction in NFK level incubated for 48 hrs by RFMS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P9SPubMed
LigandPNGBDBM50560789(CHEMBL4779878)copy SMILES
Affinity DataIC50: 2nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50560790(CHEMBL4741283)copy SMILES
Affinity DataIC50: 2nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50560816(CHEMBL4756510)copy SMILES
Affinity DataIC50: 2.40nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50578649(CHEMBL4866113)copy SMILES
Affinity DataIC50: 2.60nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P9SPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50578650(CHEMBL4866976)copy SMILES
Affinity DataIC50: 2.60nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P9SPubMed
LigandPNGBDBM50560800(CHEMBL4779197)copy SMILES
Affinity DataIC50: 2.60nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50578666(CHEMBL4859064)copy SMILES
Affinity DataIC50: 2.80nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P9SPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50578666(CHEMBL4859064)copy SMILES
Affinity DataIC50: 2.80nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P9SPubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
MD Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50152131(CHEMBL3781917)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2BF6PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50578668(CHEMBL4863359)copy SMILES
Affinity DataIC50: 3.40nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P9SPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50126143(Epacadostat | INCB-024360)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibition of recombinant human His-tagged IDO1 (Ala2 to Gly403 residues) expressed in Escherichia coli using tryptophan as substrate preincubated fo...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM506659(4-chloro-N-((R)-cyclo- propyl((1R,3s,5S,6r)-3- (5,...)copy SMILES
Affinity DataIC50: 3.60nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P9SPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50578672(CHEMBL4869547)copy SMILES
Affinity DataIC50: 3.90nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P9SPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50578655(CHEMBL4856417)copy SMILES
Affinity DataIC50: 4nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P9SPubMed
LigandPNGBDBM50560793(CHEMBL4788945)copy SMILES
Affinity DataIC50: 4nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50560813(CHEMBL4746711)copy SMILES
Affinity DataIC50: 4nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
LigandPNGBDBM50560785(CHEMBL4754431)copy SMILES
Affinity DataIC50: 4nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
Displayed 1 to 50 (of 453 total ) | Next | Last >>
Jump to: