Compile Data Set for Download or QSAR
Found 582 with Last Name = 'pinchman' and Initial = 'jr'
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM628467(Example 19 in WO2023025307 | US11795173, Comp. Ex....)copy SMILES
Affinity DataIC50: 3.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM628467(Example 19 in WO2023025307 | US11795173, Comp. Ex....)copy SMILES
Affinity DataIC50: 3.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM628468(Example 18 in WO2023025307 | US11795173, Comp. Ex....)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM628468(Example 18 in WO2023025307 | US11795173, Comp. Ex....)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM628469(Example 64 in WO2023025307 | US11795173, Comp. Ex....)copy SMILES
Affinity DataIC50: 4.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM633215(US20230348473, Comp. Ex. 3)copy SMILES
Affinity DataIC50: 4.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM628440(US11795173, Example 22 | US11795173, Example 24 | ...)copy SMILES
Affinity DataIC50: 5.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM628440(US11795173, Example 22 | US11795173, Example 24 | ...)copy SMILES
Affinity DataIC50: 5.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM628371((Example 19 in WO2023025307) | US11795173, Example...)copy SMILES
Affinity DataIC50: 6.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM628371((Example 19 in WO2023025307) | US11795173, Example...)copy SMILES
Affinity DataIC50: 6.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM628440(US11795173, Example 22 | US11795173, Example 24 | ...)copy SMILES
Affinity DataIC50: 7.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM628440(US11795173, Example 22 | US11795173, Example 24 | ...)copy SMILES
Affinity DataIC50: 7.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM628371((Example 19 in WO2023025307) | US11795173, Example...)copy SMILES
Affinity DataIC50: 8.10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM628371((Example 19 in WO2023025307) | US11795173, Example...)copy SMILES
Affinity DataIC50: 8.10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM628453(US11795173, Example 21)copy SMILES
Affinity DataIC50: 8.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM628453(US11795173, Example 21)copy SMILES
Affinity DataIC50: 8.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM628470(Example 4 in CN115232129A | US11795173, Comp. Ex. ...)copy SMILES
Affinity DataIC50: 8.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM633216(US20230348473, Comp. Ex. 4)copy SMILES
Affinity DataIC50: 8.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM628457(US11795173, Example 25)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM628457(US11795173, Example 25)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM628444(US11795173, Example 12)copy SMILES
Affinity DataIC50: 9.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM628444(US11795173, Example 12)copy SMILES
Affinity DataIC50: 9.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetBcl-2-like protein 1(Homo sapiens (Human))TBA
LigandPNGBDBM50270877((R)-4-(4-((2-(4-chlorophenyl)-5,5-dimethylcyclohex...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))TBA
LigandPNGBDBM552911(2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4-(4-((4,4-di...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR51BHUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))TBA
LigandPNGBDBM552914(2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4-(4-((4,4-di...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR51BHUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))TBA
LigandPNGBDBM555320(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((2-(3...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR51BHUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))TBA
LigandPNGBDBM552934((R)-4-(4-((2-(3-chlorobicyclo[1.1.1]pentan-1-yl)-5...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR51BHUS Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))TBA
LigandPNGBDBM552934((R)-4-(4-((2-(3-chlorobicyclo[1.1.1]pentan-1-yl)-5...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR51BHUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))TBA
LigandPNGBDBM552931((R)-4-(4-((5,5-dimethyl-2-(3-methylbicyclo[1.1.1]p...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR51BHUS Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))TBA
LigandPNGBDBM552931((R)-4-(4-((5,5-dimethyl-2-(3-methylbicyclo[1.1.1]p...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR51BHUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))TBA
LigandPNGBDBM552935((R)-4-(4-((4,4-dimethyl-2-(3-methylbicyclo[1.1.1]p...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR51BHUS Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))TBA
LigandPNGBDBM552935((R)-4-(4-((4,4-dimethyl-2-(3-methylbicyclo[1.1.1]p...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR51BHUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))TBA
LigandPNGBDBM552936((R)-4-(4-((2-(3-Ethylbicyclo[1.1.1]pentan-1-yl)-4,...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR51BHUS Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))TBA
LigandPNGBDBM552936((R)-4-(4-((2-(3-Ethylbicyclo[1.1.1]pentan-1-yl)-4,...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR51BHUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))TBA
LigandPNGBDBM555333((R)-4-(4-((2-(3-(difluoromethyl)bicyclo[1.1.1]pent...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR51BHUS Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))TBA
LigandPNGBDBM555333((R)-4-(4-((2-(3-(difluoromethyl)bicyclo[1.1.1]pent...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR51BHUS Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM628442(US11795173, Example 10)copy SMILES
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM628446(US11795173, Example 14)copy SMILES
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM628460(US11795173, Example 28 | US11795173, Example 33 | ...)copy SMILES
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))TBA
LigandPNGBDBM555334((R)-4-(4-((2-(3-(difluoromethyl)bicyclo[1.1.1]pent...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR51BHUS Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))TBA
LigandPNGBDBM555334((R)-4-(4-((2-(3-(difluoromethyl)bicyclo[1.1.1]pent...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR51BHUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))TBA
LigandPNGBDBM552939((R)-4-(4-((4,4-dimethyl-2-(3-methylbicyclo[1.1.1]p...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR51BHUS Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))TBA
LigandPNGBDBM552939((R)-4-(4-((4,4-dimethyl-2-(3-methylbicyclo[1.1.1]p...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR51BHUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))TBA
LigandPNGBDBM555336((R)-4-(4-((2-(3-(difluoromethyl)bicyclo[1.1.1]pent...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR51BHUS Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))TBA
LigandPNGBDBM555336((R)-4-(4-((2-(3-(difluoromethyl)bicyclo[1.1.1]pent...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR51BHUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))TBA
LigandPNGBDBM555337((R)-4-(4-((2-(3-(Difluoromethyl)bicyclo[1.1.1]pent...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR51BHUS Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))TBA
LigandPNGBDBM555337((R)-4-(4-((2-(3-(Difluoromethyl)bicyclo[1.1.1]pent...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR51BHUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))TBA
LigandPNGBDBM555338((R)-4-(4-((2-(3-(Difluoromethyl)bicyclo[1.1.1]pent...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR51BHUS Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))TBA
LigandPNGBDBM555338((R)-4-(4-((2-(3-(Difluoromethyl)bicyclo[1.1.1]pent...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR51BHUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))TBA
LigandPNGBDBM555339((R)-4-(4-((2-(3-(Difluoromethyl)bicyclo[1.1.1]pent...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR51BHUS Patent
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