Compile Data Set for Download or QSAR
Found 601 with Last Name = 'pruitt' and Initial = 'jr'
TargetCoagulation factor X(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM12751(1-(3-carbamimidoylphenyl)-3-methyl-N-[4-(2-sulfamo...)copy SMILEScopy InChI
Affinity DataKi:  0.0130nMAssay Description:Tested in vitro for inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1MP2PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50097624(3-(3-Carbamimidoyl-phenyl)-3H-[1,2,3]triazole-4-ca...)copy SMILEScopy InChI
Affinity DataKi:  0.0230nMAssay Description:Binding affinity towards human Serine protease FXaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0MZ2PubMed
TargetCoagulation factor X(Oryctolagus cuniculus)
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM12751(1-(3-carbamimidoylphenyl)-3-methyl-N-[4-(2-sulfamo...)copy SMILEScopy InChI
Affinity DataKi:  0.0300nMAssay Description:Binding affinity towards human trypsinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0MZ2PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM12751(1-(3-carbamimidoylphenyl)-3-methyl-N-[4-(2-sulfamo...)copy SMILEScopy InChI
Affinity DataKi:  0.0300nMAssay Description:Binding affinity towards Rabbit Coagulation factor X in a rabbit arterio-venous (A-V) shunt modelMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0MZ2PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50097626(1-(3-Carbamimidoyl-phenyl)-1H-tetrazole-5-carboxyl...)copy SMILEScopy InChI
Affinity DataKi:  0.0370nMAssay Description:Binding affinity towards human Serine protease FXaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0MZ2PubMed
TargetProthrombin(Homo sapiens (Human))
DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50288632(Boropeptide | CHEMBL607008)copy SMILEScopy InChI
Affinity DataKi:  0.0400nMAssay Description:Binding affinity towards thrombin was tested.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2542MRMPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50369433(CHEMBL1202108)copy SMILEScopy InChI
Affinity DataKi:  0.0400nMAssay Description:Binding affinity to purified human coagulation factor Xa (FXa)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P616CPubMed
TargetProthrombin(Homo sapiens (Human))
DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50369433(CHEMBL1202108)copy SMILEScopy InChI
Affinity DataKi:  0.0450nMAssay Description:The binding affinity towards thrombin obtained from human purified enzymes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P616CPubMed
TargetProthrombin(Homo sapiens (Human))
DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50069928(Boropeptide analogue | CHEMBL102385)copy SMILEScopy InChI
Affinity DataKi:  0.0600nMAssay Description:Binding affinity towards thrombin was tested.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2542MRMPubMed
TargetProthrombin(Homo sapiens (Human))
DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50069926(Boropeptide analogue | CHEMBL105137)copy SMILEScopy InChI
Affinity DataKi:  0.0600nMAssay Description:Binding affinity towards thrombin was tested.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2542MRMPubMed
TargetCoagulation factor X(Oryctolagus cuniculus)
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50097625(4-(3-Carbamimidoyl-phenyl)-2-methyl-thiazole-5-car...)copy SMILEScopy InChI
Affinity DataKi:  0.0800nMAssay Description:Binding affinity towards human trypsinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0MZ2PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50097625(4-(3-Carbamimidoyl-phenyl)-2-methyl-thiazole-5-car...)copy SMILEScopy InChI
Affinity DataKi:  0.0800nMAssay Description:Binding affinity towards Rabbit Coagulation factor X in a rabbit arterio-venous (A-V) shunt modelMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0MZ2PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50087536(3-(3-Carbamimidoyl-phenyl)-isoxazole-4-carboxylic ...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5D63PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50087533(3-(3-Carbamimidoyl-phenyl)-isoxazole-4-carboxylic ...)copy SMILEScopy InChI
Affinity DataKi:  0.150nMAssay Description:Binding affinity towards human Serine protease FXaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0MZ2PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM12657(1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2-(methylsul...)copy SMILEScopy InChI
Affinity DataKi:  0.150nMAssay Description:Tested in vitro for inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50087533(3-(3-Carbamimidoyl-phenyl)-isoxazole-4-carboxylic ...)copy SMILEScopy InChI
Affinity DataKi:  0.150nMAssay Description:Inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5D63PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50096095(2-(3-Carbamimidoyl-phenyl)-2H-pyrazole-3-carboxyli...)copy SMILEScopy InChI
Affinity DataKi:  0.160nMAssay Description:Binding affinity towards human Serine protease FXaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0MZ2PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50097620(3-(3-Carbamimidoyl-phenyl)-1-methyl-1H-pyrazole-4-...)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Binding affinity towards human Serine protease FXaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0MZ2PubMed
TargetProthrombin(Homo sapiens (Human))
DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50069933(Boropeptide analogue | CHEMBL102916)copy SMILEScopy InChI
Affinity DataKi:  0.280nMAssay Description:Binding affinity towards thrombin was tested.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2542MRMPubMed
TargetProthrombin(Homo sapiens (Human))
DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50069172(Boronate Ester analogue | CHEMBL423259)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Inhibition against human thrombinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P84B1PPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM12657(1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2-(methylsul...)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Tested in vitro for inhibition of rabbit Coagulation factor XMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50069935(Boropeptide analogue | CHEMBL320213)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Binding affinity towards thrombin was tested.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2542MRMPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50097619(1-(3-Carbamimidoyl-phenyl)-4-methyl-1H-imidazole-2...)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Binding affinity towards human Serine protease FXaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0MZ2PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50097621(1-(3-Carbamimidoyl-phenyl)-1H-imidazole-2-carboxyl...)copy SMILEScopy InChI
Affinity DataKi:  0.330nMAssay Description:Binding affinity towards human Serine protease FXaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0MZ2PubMed
TargetProthrombin(Homo sapiens (Human))
DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50069931(Boropeptide analogue | CHEMBL105212)copy SMILEScopy InChI
Affinity DataKi:  0.360nMAssay Description:Binding affinity towards thrombin was tested.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2542MRMPubMed
TargetProthrombin(Homo sapiens (Human))
DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50069937(Boropeptide analogue | CHEMBL102779)copy SMILEScopy InChI
Affinity DataKi:  0.370nMAssay Description:Binding affinity towards thrombin was tested.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2542MRMPubMed
TargetCoagulation factor X(Oryctolagus cuniculus)
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50087533(3-(3-Carbamimidoyl-phenyl)-isoxazole-4-carboxylic ...)copy SMILEScopy InChI
Affinity DataKi:  0.400nMAssay Description:Inhibitory activity of the compound was tested against rabbit Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5D63PubMed
TargetCoagulation factor X(Oryctolagus cuniculus)
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50087533(3-(3-Carbamimidoyl-phenyl)-isoxazole-4-carboxylic ...)copy SMILEScopy InChI
Affinity DataKi:  0.400nMAssay Description:Binding affinity towards human trypsinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0MZ2PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50097632(4-(3-Carbamimidoyl-phenyl)-2-methyl-oxazole-5-carb...)copy SMILEScopy InChI
Affinity DataKi:  0.400nMAssay Description:Binding affinity towards human Serine protease FXaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0MZ2PubMed
TargetProthrombin(Homo sapiens (Human))
DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50069936(Boropeptide analogue | CHEMBL319050)copy SMILEScopy InChI
Affinity DataKi:  0.410nMAssay Description:Binding affinity towards thrombin was tested.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2542MRMPubMed
TargetProthrombin(Homo sapiens (Human))
DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50069924(Boropeptide analogue | CHEMBL419734)copy SMILEScopy InChI
Affinity DataKi:  0.420nMAssay Description:Binding affinity towards thrombin was tested.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2542MRMPubMed
TargetProthrombin(Homo sapiens (Human))
DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50069930(Boropeptide analogue | CHEMBL320019)copy SMILEScopy InChI
Affinity DataKi:  0.430nMAssay Description:Binding affinity towards thrombin was tested.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2542MRMPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135953(2-(2-Aminomethyl-phenyl)-5-trifluoromethyl-2H-pyra...)copy SMILEScopy InChI
Affinity DataKi:  0.460nMAssay Description:Tested in vitro for inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1MP2PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50087540(3-(3-Carbamimidoyl-phenyl)-5-hydroxymethyl-isoxazo...)copy SMILEScopy InChI
Affinity DataKi:  0.5nMAssay Description:Inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5D63PubMed
TargetProthrombin(Homo sapiens (Human))
DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50069929(Boropeptide analogue | CHEMBL103078)copy SMILEScopy InChI
Affinity DataKi:  0.530nMAssay Description:Binding affinity towards thrombin was tested.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2542MRMPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135943(2-(2-Aminomethyl-4-methoxy-phenyl)-5-trifluorometh...)copy SMILEScopy InChI
Affinity DataKi:  0.540nMAssay Description:Tested in vitro for inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1MP2PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50087538((4S,5S)-3-(3-Carbamimidoyl-phenyl)-5-methoxymethyl...)copy SMILEScopy InChI
Affinity DataKi:  0.550nMAssay Description:Inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5D63PubMed
TargetProthrombin(Homo sapiens (Human))
DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50069938(Boropeptide analogue | CHEMBL103077)copy SMILEScopy InChI
Affinity DataKi:  0.580nMAssay Description:Binding affinity towards thrombin was tested.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2542MRMPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50087532(3-(3-Carbamimidoyl-phenyl)-5-methoxymethyl-isoxazo...)copy SMILEScopy InChI
Affinity DataKi:  0.630nMAssay Description:Inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5D63PubMed
TargetCoagulation factor X(Oryctolagus cuniculus)
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50087538((4S,5S)-3-(3-Carbamimidoyl-phenyl)-5-methoxymethyl...)copy SMILEScopy InChI
Affinity DataKi:  0.640nMAssay Description:Inhibitory activity of the compound was tested against rabbit Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5D63PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50087535(3-(3-Carbamimidoyl-phenyl)-5-methoxymethyl-isoxazo...)copy SMILEScopy InChI
Affinity DataKi:  0.75nMAssay Description:Inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5D63PubMed
TargetCoagulation factor X(Oryctolagus cuniculus)
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50079252(3-(3-Carbamimidoyl-phenyl)-5-methoxymethyl-4,5-dih...)copy SMILEScopy InChI
Affinity DataKi:  0.800nMAssay Description:Inhibitory activity of the compound was tested against rabbit Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5D63PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50096084(1-(3-Carbamimidoyl-phenyl)-1H-pyrrole-2-carboxylic...)copy SMILEScopy InChI
Affinity DataKi:  0.800nMAssay Description:Binding affinity towards human Serine protease FXaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0MZ2PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50097631(4-(3-Carbamimidoyl-phenyl)-thiazole-5-carboxylic a...)copy SMILEScopy InChI
Affinity DataKi:  0.820nMAssay Description:Binding affinity towards human Serine protease FXaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0MZ2PubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50079211(CHEMBL327404 | {3-(3-Carbamimidoyl-phenyl)-5-[5-(2...)copy SMILEScopy InChI
Affinity DataKi:  0.830nMAssay Description:Binding affinity to purified human coagulation factor Xa (FXa)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P616CPubMed
TargetProthrombin(Homo sapiens (Human))
DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50069923(Boropeptide analogue | CHEMBL104331)copy SMILEScopy InChI
Affinity DataKi:  0.830nMAssay Description:Binding affinity towards thrombin was tested.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2542MRMPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50079211(CHEMBL327404 | {3-(3-Carbamimidoyl-phenyl)-5-[5-(2...)copy SMILEScopy InChI
Affinity DataKi:  0.830nMAssay Description:Binding affinity to purified human coagulation factor Xa (FXa)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P616CPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135960(2-(2-Aminomethyl-4-methoxy-phenyl)-5-trifluorometh...)copy SMILEScopy InChI
Affinity DataKi:  0.880nMAssay Description:Tested in vitro for inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1MP2PubMed
TargetProthrombin(Homo sapiens (Human))
DuPont Merck Pharmaceutical Company

Curated by ChEMBL
LigandPNGBDBM50069932(Boropeptide analogue | CHEMBL105393)copy SMILEScopy InChI
Affinity DataKi:  0.890nMAssay Description:Binding affinity towards thrombin was tested.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2542MRMPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135945(1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...)copy SMILEScopy InChI
Affinity DataKi:  0.910nMAssay Description:Tested in vitro for inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
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