Compile Data Set for Download or QSAR
Found 114 with Last Name = 'denton' and Initial = 'js'
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287520(CHEMBL4159883)copy SMILEScopy InChI
Affinity DataKi:  2.80E+4nMAssay Description:Displacement of fluorescent-labelled dofetilide from human ERG expressed in HEK293 cell membrane homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287559(CHEMBL4170197)copy SMILEScopy InChI
Affinity DataKi: >4.00E+4nMAssay Description:Displacement of fluorescent-labelled dofetilide from human ERG expressed in HEK293 cell membrane homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287554(CHEMBL4162926)copy SMILEScopy InChI
Affinity DataKi: >4.00E+4nMAssay Description:Displacement of fluorescent-labelled dofetilide from human ERG expressed in HEK293 cell membrane homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287553(CHEMBL4166791)copy SMILEScopy InChI
Affinity DataKi: >4.00E+4nMAssay Description:Displacement of fluorescent-labelled dofetilide from human ERG expressed in HEK293 cell membrane homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287557(CHEMBL4159568)copy SMILEScopy InChI
Affinity DataKi: >4.00E+4nMAssay Description:Displacement of fluorescent-labelled dofetilide from human ERG expressed in HEK293 cell membrane homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287519(CHEMBL4172084)copy SMILEScopy InChI
Affinity DataKi: >4.00E+4nMAssay Description:Displacement of fluorescent-labelled dofetilide from human ERG expressed in HEK293 cell membrane homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287556(CHEMBL4161489)copy SMILEScopy InChI
Affinity DataKi: >4.00E+4nMAssay Description:Displacement of fluorescent-labelled dofetilide from human ERG expressed in HEK293 cell membrane homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287552(CHEMBL4175004)copy SMILEScopy InChI
Affinity DataKi: >4.00E+4nMAssay Description:Displacement of fluorescent-labelled dofetilide from human ERG expressed in HEK293 cell membrane homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287520(CHEMBL4159883)copy SMILEScopy InChI
Affinity DataKi: >4.00E+4nMAssay Description:Displacement of fluorescent-labelled dofetilide from human ERG expressed in HEK293 cell membrane homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287555(CHEMBL4174695)copy SMILEScopy InChI
Affinity DataKi: >4.00E+4nMAssay Description:Displacement of fluorescent-labelled dofetilide from human ERG expressed in HEK293 cell membrane homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287558(CHEMBL1333494)copy SMILEScopy InChI
Affinity DataKi: >4.00E+4nMAssay Description:Displacement of fluorescent-labelled dofetilide from human ERG expressed in HEK293 cell membrane homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287519(CHEMBL4172084)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of human ROMK2 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287519(CHEMBL4172084)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of human ROMK2 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287520(CHEMBL4159883)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of human ROMK1 expressed in HEK293 cells at -75 mV holding potential by whole cell patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287555(CHEMBL4174695)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of human ROMK1 expressed in HEK293 cells at -75 mV holding potential by whole cell patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287555(CHEMBL4174695)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:Inhibition of human ROMK2 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287555(CHEMBL4174695)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:Inhibition of human ROMK2 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287552(CHEMBL4175004)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Inhibition of human ROMK2 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287552(CHEMBL4175004)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Inhibition of human ROMK2 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287553(CHEMBL4166791)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human ROMK2 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287556(CHEMBL4161489)copy SMILEScopy InChI
Affinity DataIC50: 104nMAssay Description:Inhibition of human ROMK1 expressed in HEK293 cells at -75 mV holding potential by whole cell patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287553(CHEMBL4166791)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of human ROMK2 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287520(CHEMBL4159883)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:Inhibition of human ROMK2 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287520(CHEMBL4159883)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of human ROMK2 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287520(CHEMBL4159883)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of human ROMK2 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287520(CHEMBL4159883)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of human ROMK2 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287556(CHEMBL4161489)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of human ROMK2 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287556(CHEMBL4161489)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of human ROMK2 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287520(CHEMBL4159883)copy SMILEScopy InChI
Affinity DataIC50: 391nMAssay Description:Inhibition of human ROMK1 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287521(CHEMBL2146753)copy SMILEScopy InChI
Affinity DataIC50: 398nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287520(CHEMBL4159883)copy SMILEScopy InChI
Affinity DataIC50: 398nMAssay Description:Inhibition of human ROMK1 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287521(CHEMBL2146753)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287554(CHEMBL4162926)copy SMILEScopy InChI
Affinity DataIC50: 440nMAssay Description:Inhibition of human ROMK2 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287554(CHEMBL4162926)copy SMILEScopy InChI
Affinity DataIC50: 440nMAssay Description:Inhibition of human ROMK2 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287521(CHEMBL2146753)copy SMILEScopy InChI
Affinity DataIC50: 744nMAssay Description:Inhibition of human ROMK1 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287555(CHEMBL4174695)copy SMILEScopy InChI
Affinity DataIC50: 777nMAssay Description:Inhibition of human ROMK1 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287521(CHEMBL2146753)copy SMILEScopy InChI
Affinity DataIC50: 794nMAssay Description:Inhibition of human ROMK1 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287555(CHEMBL4174695)copy SMILEScopy InChI
Affinity DataIC50: 794nMAssay Description:Inhibition of human ROMK1 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287556(CHEMBL4161489)copy SMILEScopy InChI
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of human ROMK1 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287556(CHEMBL4161489)copy SMILEScopy InChI
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of human ROMK1 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287557(CHEMBL4159568)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human ROMK2 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287557(CHEMBL4159568)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human ROMK2 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287558(CHEMBL1333494)copy SMILEScopy InChI
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of human ROMK2 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287559(CHEMBL4170197)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human ROMK2 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287555(CHEMBL4174695)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287520(CHEMBL4159883)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287556(CHEMBL4161489)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetPotassium channel subfamily K member 10(Homo sapiens (Human))TBA
LigandPNGBDBM50197060(CHEMBL1417584)copy SMILEScopy InChI
Affinity DataEC50:  7.70E+3nMAssay Description:Activation of human TREK2 by thallium flux mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS6006PubMed
TargetPotassium channel subfamily K member 10(Homo sapiens (Human))TBA
LigandPNGBDBM50545998(CHEMBL4745050)copy SMILES
Affinity DataEC50:  5.00E+3nMAssay Description:Activation of human TREK2 by thallium flux mobilization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS6006PubMed
TargetPotassium channel subfamily K member 10(Homo sapiens (Human))TBA
LigandPNGBDBM50545999(CHEMBL4778307)copy SMILES
Affinity DataEC50: >3.00E+4nMAssay Description:Activation of human TREK2 by thallium flux mobilization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS6006PubMed
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